SCLX vs LIXT

Comparison between Scilex Holding Company (SCLX, Company) and Lixte Biotechnology Holdings Inc (LIXT, Company).

Both SCLX and LIXT are from the Healthcare sector.

5-Year PerformanceLIXT has outperformed SCLX, delivering a return of -26.8% compared to -52.4%

SCLX vs LIXT - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SCLX(COMPANY)	LIXT(COMPANY)
Market Cap	$75M	$75M
Max Drawdown	99.23%	99.12%
Sharpe Ratio	0.86	1.78
5Y Beta	1.10	0.60
Industry	Drug Manufacturers - General	Biotechnology
P/E Ratio	-0.14	-5.85
Forward P/E	2.66	N/A
PEG Ratio	-0.00	0.00
5Y EPS CAGR	N/A	24.68%
Debt to Equity	-32.41%	0.00%
Free Cash Flow Yield	-4.59%	-5.80%
P/S Ratio	1.83	20.35
P/B Ratio	28.85	10.01

Market Cap

Winner

SCLX

$75M

LIXT

$75M

Max Drawdown

SCLX

99.23%

Winner

LIXT

99.12%

Sharpe Ratio

SCLX

0.86

Winner

LIXT

1.78

5Y Beta

SCLX

1.10

Winner

LIXT

0.60

Industry

SCLX

Drug Manufacturers - General

LIXT

Biotechnology

P/E Ratio

SCLX

-0.14

Winner

LIXT

-5.85

Forward P/E

SCLX

2.66

LIXT

N/A

PEG Ratio

Winner

SCLX

-0.00

LIXT

0.00

5Y EPS CAGR

SCLX

N/A

LIXT

24.68%

Debt to Equity

Winner

SCLX

-32.41%

LIXT

0.00%

Free Cash Flow Yield

Winner

SCLX

-4.59%

LIXT

-5.80%

P/S Ratio

Winner

SCLX

1.83

LIXT

20.35

P/B Ratio

SCLX

28.85

Winner

LIXT

10.01

SCLX vs LIXT - Historical Returns

Returns include dividend reinvestment.

Period	SCLX	LIXT
1 month	+24.82%	+22.09%
3 months	-3.52%	+91.05%
6 months	-48.89%	+52.84%
1 year	+63.78%	+372.56%
5 years(CAGR)	-52.41%	-26.76%
10 years(CAGR)	N/A	-6.41%
Max(CAGR)	-50.47%	-7.27%

Winner

SCLX

+24.82%

LIXT

+22.09%

SCLX

-3.52%

Winner

LIXT

+91.05%

SCLX

-48.89%

Winner

LIXT

+52.84%

SCLX

+63.78%

Winner

LIXT

+372.56%

5Y(CAGR)

SCLX

-52.41%

Winner

LIXT

-26.76%

10Y(CAGR)

SCLX

N/A

LIXT

-6.41%

Max(CAGR)

SCLX

-50.47%

Winner

LIXT

-7.27%

SCLX vs LIXT - Annual Returns (2010 - 2026)

Returns include dividend reinvestment.

Year	SCLX	LIXT
2026	-35.06%	+61.20%
2025	-20.13%	+77.03%
2024	-79.10%	-11.37%
2023	-61.61%	-53.68%
2022	-60.30%	-60.85%
2021	+1.93%	-62.93%
2020	N/A	-37.84%
2019	N/A	-27.66%
2018	N/A	+447.35%
2017	N/A	+37.50%
2016	N/A	-68.87%
2015	N/A	+22.92%
2014	N/A	+20.00%
2013	N/A	-48.00%
2012	N/A	-50.00%
2011	N/A	-20.63%
2010	N/A	+80.00%

SCLX vs LIXT Drawdown Comparison

The maximum drawdown for SCLX was -99.23%, occurring on Apr 22, 2025. This drawdown has not yet recovered.

The maximum drawdown for LIXT was -99.12%, occurring on Jun 27, 2025. This drawdown has not yet recovered.

The current SCLX drawdown is -98.36%. The current LIXT drawdown is -92.36%.

Rank	SCLX	LIXT
#1	-99.23% Apr 12, 2023 - Apr 22, 2025	-99.12% Aug 26, 2019 - Jun 27, 2025
#2	-72.67% Nov 8, 2022 - Jan 19, 2023	-90.82% Apr 4, 2011 - Aug 22, 2018
#3	-42.23% Jan 20, 2023 - Apr 5, 2023	-88.00% May 19, 2010 - Sep 20, 2010
#4	-16.08% Oct 26, 2022 - Nov 8, 2022	-49.00% Aug 22, 2018 - Oct 12, 2018
#5	-8.13% Apr 10, 2023 - Apr 12, 2023	-46.15% Nov 1, 2018 - Aug 22, 2019
#6	-1.26% Jun 27, 2022 - Oct 13, 2022	-25.93% Oct 12, 2018 - Oct 18, 2018
#7	-1.21% Mar 11, 2021 - Apr 19, 2021	-20.00% Feb 14, 2011 - Mar 17, 2011
#8	-0.80% Apr 19, 2021 - Aug 30, 2021	-18.75% Oct 18, 2018 - Nov 1, 2018
#9	-0.59% Nov 2, 2021 - Jan 24, 2022	-2.26% Aug 22, 2019 - Aug 26, 2019
#10	-0.50% Oct 18, 2021 - Nov 2, 2021	N/A
#11	-0.40% Jan 24, 2022 - Feb 2, 2022	N/A
#12	-0.39% Mar 17, 2022 - May 4, 2022	N/A
#13	-0.29% May 5, 2022 - May 25, 2022	N/A
#14	-0.29% May 27, 2022 - Jun 21, 2022	N/A
#15	-0.28% Sep 14, 2021 - Oct 14, 2021	N/A