SBIO vs AVMU

Comparison between ALPS MEDICAL BREAKTHROUGHS ETF (SBIO, ETF) and AVANTIS CORE MUNICIPAL FIXED INCOME ETF (AVMU, ETF).

5-Year PerformanceSBIO has outperformed AVMU, delivering a return of +1.9% compared to +0.9%

SBIO vs AVMU - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SBIO(ETF)	AVMU(ETF)
Net Assets	$162M	$162M
Expense Ratio	0.50%	0.15%
Max Drawdown	63.06%	14.15%
Sharpe Ratio	1.79	1.32
5Y Beta	1.03	0.03
P/E Ratio	-12.79	N/A
5Y Dividends CAGR	9.24%	61.64%
Debt to Equity	2.08%	N/A
P/S Ratio	6.98	N/A
P/B Ratio	3.94	N/A

Net Assets

SBIO

$162M

Winner

AVMU

$162M

Expense Ratio

SBIO

0.50%

Winner

AVMU

0.15%

Max Drawdown

SBIO

63.06%

Winner

AVMU

14.15%

Sharpe Ratio

Winner

SBIO

1.79

AVMU

1.32

5Y Beta

SBIO

1.03

Winner

AVMU

0.03

P/E Ratio

SBIO

-12.79

AVMU

N/A

5Y Dividends CAGR

SBIO

9.24%

Winner

AVMU

61.64%

Debt to Equity

SBIO

2.08%

AVMU

N/A

P/S Ratio

SBIO

6.98

AVMU

N/A

P/B Ratio

SBIO

3.94

AVMU

N/A

SBIO vs AVMU - Historical Returns

Returns include dividend reinvestment.

Period	SBIO	AVMU
1 month	-4.31%	+0.54%
3 months	+5.14%	+1.09%
6 months	+2.95%	+2.85%
1 year	+68.66%	+8.19%
5 years(CAGR)	+1.91%	+0.87%
10 years(CAGR)	+9.09%	N/A
Max(CAGR)	+7.58%	+0.92%

SBIO

-4.31%

Winner

AVMU

+0.54%

Winner

SBIO

+5.14%

AVMU

+1.09%

Winner

SBIO

+2.95%

AVMU

+2.85%

Winner

SBIO

+68.66%

AVMU

+8.19%

5Y(CAGR)

Winner

SBIO

+1.91%

AVMU

+0.87%

10Y(CAGR)

SBIO

+9.09%

AVMU

N/A

Max(CAGR)

Winner

SBIO

+7.58%

AVMU

+0.92%

SBIO vs AVMU - Annual Returns (2014 - 2026)

Returns include dividend reinvestment.

Year	SBIO	AVMU
2026	+5.18%	+1.54%
2025	+53.69%	+3.68%
2024	+4.25%	+1.83%
2023	+11.05%	+4.92%
2022	-30.19%	-7.26%
2021	-17.90%	+0.26%
2020	+23.09%	+0.19%
2019	+47.58%	N/A
2018	-13.24%	N/A
2017	+44.12%	N/A
2016	-25.20%	N/A
2015	+26.42%	N/A
2014	+0.00%	N/A

SBIO vs AVMU Drawdown Comparison

The maximum drawdown for SBIO was -63.06%, occurring on Oct 27, 2023. This drawdown has not yet recovered.

The maximum drawdown for AVMU was -12.41%, occurring on Oct 25, 2022. Recovery took 1062 trading sessions.

The current SBIO drawdown is -13.96%. The current AVMU drawdown is -0.54%.

Rank	SBIO	AVMU
#1	-63.06% Feb 8, 2021 - Oct 27, 2023	-12.41% Jul 19, 2021 - Oct 9, 2025
#2	-49.69% Jul 17, 2015 - Jun 6, 2018	-3.32% Feb 27, 2026 - Mar 27, 2026
#3	-39.30% Dec 24, 2019 - Jun 23, 2020	-2.18% Feb 11, 2021 - Jun 10, 2021
#4	-32.42% Sep 28, 2018 - Nov 25, 2019	-0.74% Oct 27, 2025 - Dec 16, 2025
#5	-13.78% Apr 23, 2015 - May 20, 2015	-0.59% Jun 10, 2021 - Jul 7, 2021
#6	-13.03% Jun 23, 2020 - Oct 7, 2020	-0.40% Jan 15, 2026 - Jan 27, 2026
#7	-11.31% Mar 19, 2015 - Apr 13, 2015	-0.30% Jan 5, 2021 - Jan 26, 2021
#8	-6.72% Jun 6, 2018 - Sep 28, 2018	-0.19% Dec 29, 2025 - Jan 2, 2026
#9	-6.30% Jan 27, 2015 - Feb 17, 2015	-0.14% Feb 17, 2026 - Feb 20, 2026
#10	-6.29% Jun 22, 2015 - Jul 13, 2015	-0.13% Jul 8, 2021 - Jul 15, 2021
#11	-6.19% Dec 22, 2020 - Jan 7, 2021	-0.12% Feb 10, 2026 - Feb 12, 2026
#12	-4.88% Oct 13, 2020 - Oct 27, 2020	-0.11% Dec 14, 2020 - Dec 28, 2020
#13	-3.81% Jan 14, 2015 - Jan 20, 2015	-0.11% Jan 2, 2026 - Jan 6, 2026
#14	-3.39% Oct 27, 2020 - Nov 4, 2020	-0.07% Oct 9, 2025 - Oct 13, 2025
#15	-3.31% Jan 26, 2021 - Feb 1, 2021	-0.05% Jan 28, 2021 - Feb 1, 2021