RNLX vs BCYC

Comparison between Renalytix Plc (RNLX, Company) and Bicycle Therapeutics Plc (BCYC, Company).

5-Year PerformanceBCYC has outperformed RNLX, delivering a return of -35.7% compared to -72.5%

RNLX vs BCYC - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	RNLX(COMPANY)	BCYC(COMPANY)
Market Cap	$295M	$293M
Max Drawdown	99.87%	93.67%
Sharpe Ratio	-2.14	-1.41
5Y Beta	N/A	1.27
Industry	N/A	Biotechnology
P/E Ratio	-10.08	-1.33
PEG Ratio	N/A	-0.18
5Y EPS CAGR	N/A	11.06%
Debt to Equity	171.49%	0.00%
Free Cash Flow Yield	-8.30%	-78.95%
P/S Ratio	125.29	4.55
P/B Ratio	-26.03	0.52

Market Cap

Winner

RNLX

$295M

BCYC

$293M

Max Drawdown

RNLX

99.87%

Winner

BCYC

93.67%

Sharpe Ratio

RNLX

-2.14

Winner

BCYC

-1.41

5Y Beta

RNLX

N/A

BCYC

1.27

Industry

RNLX

N/A

BCYC

Biotechnology

P/E Ratio

Winner

RNLX

-10.08

BCYC

-1.33

PEG Ratio

RNLX

N/A

BCYC

-0.18

5Y EPS CAGR

RNLX

N/A

BCYC

11.06%

Debt to Equity

RNLX

171.49%

Winner

BCYC

0.00%

Free Cash Flow Yield

Winner

RNLX

-8.30%

BCYC

-78.95%

P/S Ratio

RNLX

125.29

Winner

BCYC

4.55

P/B Ratio

Winner

RNLX

-26.03

BCYC

0.52

RNLX vs BCYC - Historical Returns

Returns include dividend reinvestment.

Period	RNLX	BCYC
1 month	+0.78%	-2.27%
3 months	-51.69%	-20.04%
6 months	-66.49%	-44.32%
1 year	N/A	-55.00%
5 years(CAGR)	-72.53%	-35.73%
Max(CAGR)	-61.31%	-14.60%

Winner

RNLX

+0.78%

BCYC

-2.27%

RNLX

-51.69%

Winner

BCYC

-20.04%

RNLX

-66.49%

Winner

BCYC

-44.32%

RNLX

N/A

BCYC

-55.00%

5Y(CAGR)

RNLX

-72.53%

Winner

BCYC

-35.73%

Max(CAGR)

RNLX

-61.31%

Winner

BCYC

-14.60%

RNLX vs BCYC - Annual Returns (2019 - 2026)

Returns include dividend reinvestment.

Year	RNLX	BCYC
2026	-67.67%	-42.07%
2025	-5.97%	-50.70%
2024	-51.27%	-24.08%
2023	-79.79%	-39.73%
2022	-87.95%	-50.25%
2021	-3.05%	+217.03%
2020	+18.52%	+82.79%
2019	N/A	-21.42%

RNLX vs BCYC Drawdown Comparison

The maximum drawdown for RNLX was -99.87%, occurring on Apr 24, 2026. This drawdown has not yet recovered.

The maximum drawdown for BCYC was -93.67%, occurring on Jul 24, 2026. This drawdown has not yet recovered.

The current RNLX drawdown is -99.85%. The current BCYC drawdown is -93.67%.

Rank	RNLX	BCYC
#1	-99.87% Jul 28, 2021 - Apr 24, 2026	-93.67% Nov 15, 2021 - Jul 24, 2026
#2	-41.16% Aug 5, 2020 - Jan 5, 2021	-53.96% Jun 19, 2019 - Feb 14, 2020
#3	-24.32% Mar 15, 2021 - Apr 23, 2021	-41.61% Mar 10, 2020 - May 28, 2020
#4	-22.28% Jun 1, 2021 - Jul 28, 2021	-25.95% Feb 5, 2021 - Apr 1, 2021
#5	-18.69% Jan 25, 2021 - Mar 8, 2021	-20.84% Jul 23, 2021 - Aug 30, 2021
#6	-15.31% Apr 26, 2021 - May 24, 2021	-18.83% Feb 26, 2020 - Mar 4, 2020
#7	-13.01% Jan 5, 2021 - Jan 13, 2021	-18.70% Jul 15, 2020 - Sep 16, 2020
#8	-7.42% May 24, 2021 - Jun 1, 2021	-16.36% Apr 8, 2021 - Jul 13, 2021
#9	-5.32% Jul 23, 2020 - Jul 27, 2020	-15.98% Jun 8, 2020 - Jul 14, 2020
#10	-3.47% Jul 29, 2020 - Aug 3, 2020	-15.96% Nov 30, 2020 - Jan 14, 2021
#11	-1.93% Mar 9, 2021 - Mar 11, 2021	-15.70% Mar 4, 2020 - Mar 10, 2020
#12	-0.39% Jul 27, 2020 - Jul 29, 2020	-14.32% Jan 19, 2021 - Feb 5, 2021
#13	-0.31% Aug 3, 2020 - Aug 5, 2020	-14.18% May 24, 2019 - Jun 14, 2019
#14	N/A	-13.83% Oct 14, 2021 - Nov 15, 2021
#15	N/A	-12.02% Sep 21, 2020 - Nov 17, 2020