REPL vs ESPR

Comparison between Replimune Group Inc (REPL, Company) and Esperion Therapeutics Inc (ESPR, Company).

Both REPL and ESPR are from the Healthcare sector.

5-Year PerformanceREPL has outperformed ESPR, delivering a return of -21.2% compared to -29.6%

REPL vs ESPR - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	REPL(COMPANY)	ESPR(COMPANY)
Market Cap	$801M	$799M
Max Drawdown	96.77%	99.37%
Sharpe Ratio	1.04	1.41
5Y Beta	0.75	1.29
Industry	Biotechnology	Drug Manufacturers - Specialty & Generic
P/E Ratio	-2.45	-6.03
Forward P/E	N/A	4.64
PEG Ratio	-0.15	-0.75
5Y EPS CAGR	16.21%	-31.57%
Debt to Equity	50.14%	0.00%
Free Cash Flow Yield	-35.01%	-2.30%
P/S Ratio	N/A	1.96
P/B Ratio	4.98	98.42

Market Cap

Winner

REPL

$801M

ESPR

$799M

Max Drawdown

Winner

REPL

96.77%

ESPR

99.37%

Sharpe Ratio

REPL

1.04

Winner

ESPR

1.41

5Y Beta

Winner

REPL

0.75

ESPR

1.29

Industry

REPL

Biotechnology

ESPR

Drug Manufacturers - Specialty & Generic

P/E Ratio

REPL

-2.45

Winner

ESPR

-6.03

Forward P/E

REPL

N/A

ESPR

4.64

PEG Ratio

REPL

-0.15

Winner

ESPR

-0.75

5Y EPS CAGR

Winner

REPL

16.21%

ESPR

-31.57%

Debt to Equity

REPL

50.14%

Winner

ESPR

0.00%

Free Cash Flow Yield

REPL

-35.01%

Winner

ESPR

-2.30%

P/S Ratio

REPL

N/A

ESPR

1.96

P/B Ratio

Winner

REPL

4.98

ESPR

98.42

REPL vs ESPR - Historical Returns

Returns include dividend reinvestment.

Period	REPL	ESPR
1 month	+8.43%	+0.95%
3 months	+334.70%	+43.24%
6 months	+35.23%	-3.64%
1 year	-24.62%	+169.49%
5 years(CAGR)	-21.19%	-29.55%
10 years(CAGR)	N/A	-11.39%
Max(CAGR)	-5.66%	-10.98%

Winner

REPL

+8.43%

ESPR

+0.95%

Winner

REPL

+334.70%

ESPR

+43.24%

Winner

REPL

+35.23%

ESPR

-3.64%

REPL

-24.62%

Winner

ESPR

+169.49%

5Y(CAGR)

Winner

REPL

-21.19%

ESPR

-29.55%

10Y(CAGR)

REPL

N/A

ESPR

-11.39%

Max(CAGR)

Winner

REPL

-5.66%

ESPR

-10.98%

REPL vs ESPR - Annual Returns (2013 - 2026)

Returns include dividend reinvestment.

Year	REPL	ESPR
2026	+6.97%	-14.29%
2025	-22.61%	+68.18%
2024	+39.68%	-24.66%
2023	-68.01%	-48.80%
2022	-7.20%	+20.04%
2021	-29.11%	-81.96%
2020	+160.94%	-57.61%
2019	+36.67%	+30.45%
2018	-34.04%	-30.83%
2017	N/A	+411.18%
2016	N/A	-42.17%
2015	N/A	-46.01%
2014	N/A	+191.35%
2013	N/A	-5.24%

REPL vs ESPR Drawdown Comparison

The maximum drawdown for REPL was -96.77%, occurring on Apr 13, 2026. This drawdown has not yet recovered.

The maximum drawdown for ESPR was -99.37%, occurring on May 14, 2025. This drawdown has not yet recovered.

The current REPL drawdown is -81.92%. The current ESPR drawdown is -97.24%.

Rank	REPL	ESPR
#1	-96.77% Dec 1, 2020 - Apr 13, 2026	-99.37% May 19, 2015 - May 14, 2025
#2	-59.80% Sep 4, 2018 - Jun 4, 2020	-41.24% Oct 2, 2013 - Sep 26, 2014
#3	-27.36% Jun 25, 2020 - Aug 28, 2020	-28.66% Oct 8, 2014 - Oct 31, 2014
#4	-23.56% Aug 31, 2020 - Oct 14, 2020	-22.60% Mar 23, 2015 - May 19, 2015
#5	-15.89% Jun 8, 2020 - Jun 25, 2020	-18.82% Aug 5, 2013 - Sep 26, 2013
#6	-9.20% Aug 29, 2018 - Sep 4, 2018	-13.95% Oct 31, 2014 - Nov 12, 2014
#7	-8.89% Nov 5, 2020 - Nov 17, 2020	-12.84% Jan 14, 2015 - Feb 3, 2015
#8	-7.50% Oct 23, 2020 - Nov 4, 2020	-12.54% Dec 9, 2014 - Dec 31, 2014
#9	-4.70% Aug 16, 2018 - Aug 28, 2018	-12.35% Feb 18, 2015 - Mar 12, 2015
#10	-3.42% Aug 2, 2018 - Aug 10, 2018	-10.06% Nov 18, 2014 - Dec 4, 2014
#11	-2.98% Nov 20, 2020 - Nov 25, 2020	-6.74% Jan 12, 2015 - Jan 14, 2015
#12	-2.38% Oct 20, 2020 - Oct 22, 2020	-6.30% Jan 8, 2015 - Jan 12, 2015
#13	-1.79% Jun 4, 2020 - Jun 8, 2020	-3.45% Jun 26, 2013 - Jul 2, 2013
#14	-1.33% Aug 14, 2018 - Aug 16, 2018	-3.06% Jul 16, 2013 - Jul 29, 2013
#15	-1.12% Jul 20, 2018 - Aug 1, 2018	-2.87% Sep 26, 2014 - Sep 30, 2014