QURE vs APPN

Comparison between uniQure N.V. (QURE, Company) and Appian Corp - Class A (APPN, Company).

QURE is from the Healthcare sector, while APPN is from the Technology sector.

5-Year PerformanceQURE has outperformed APPN, delivering a return of -5.6% compared to -22.9%

QURE vs APPN - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	QURE(COMPANY)	APPN(COMPANY)
Market Cap	$1.59B	$1.59B
Max Drawdown	95.40%	92.04%
Sharpe Ratio	0.92	-0.18
5Y Beta	1.33	1.06
Industry	Biotechnology	Software - Infrastructure
P/E Ratio	-7.34	332.00
Forward P/E	27.93	416.67
PEG Ratio	0.00	0.00
5Y EPS CAGR	2.11%	N/A
Debt to Equity	33.44%	-404.34%
Free Cash Flow Yield	-10.88%	4.02%
P/S Ratio	87.74	2.14
P/B Ratio	10.62	42.82

Market Cap

QURE

$1.59B

Winner

APPN

$1.59B

Max Drawdown

QURE

95.40%

Winner

APPN

92.04%

Sharpe Ratio

Winner

QURE

0.92

APPN

-0.18

5Y Beta

QURE

1.33

Winner

APPN

1.06

Industry

QURE

Biotechnology

APPN

Software - Infrastructure

P/E Ratio

Winner

QURE

-7.34

APPN

332.00

Forward P/E

Winner

QURE

27.93

APPN

416.67

PEG Ratio

QURE

0.00

APPN

0.00

5Y EPS CAGR

QURE

2.11%

APPN

N/A

Debt to Equity

QURE

33.44%

Winner

APPN

-404.34%

Free Cash Flow Yield

QURE

-10.88%

Winner

APPN

4.02%

P/S Ratio

QURE

87.74

Winner

APPN

2.14

P/B Ratio

Winner

QURE

10.62

APPN

42.82

QURE vs APPN - Historical Returns

Returns include dividend reinvestment.

Period	QURE	APPN
1 month	+25.00%	+8.85%
3 months	+148.36%	-8.37%
6 months	+24.00%	-39.62%
1 year	+59.24%	-22.23%
5 years(CAGR)	-5.62%	-22.92%
10 years(CAGR)	+6.56%	+5.69%
Max(CAGR)	+4.93%	+5.69%

Winner

QURE

+25.00%

APPN

+8.85%

Winner

QURE

+148.36%

APPN

-8.37%

Winner

QURE

+24.00%

APPN

-39.62%

Winner

QURE

+59.24%

APPN

-22.23%

5Y(CAGR)

Winner

QURE

-5.62%

APPN

-22.92%

10Y(CAGR)

Winner

QURE

+6.56%

APPN

+5.69%

Max(CAGR)

QURE

+4.93%

Winner

APPN

+5.69%

QURE vs APPN - Annual Returns (2014 - 2026)

Returns include dividend reinvestment.

Year	QURE	APPN
2026	+13.08%	-27.39%
2025	+32.58%	+6.72%
2024	+154.83%	-6.15%
2023	-69.00%	+16.23%
2022	+5.44%	-50.55%
2021	-43.58%	-54.62%
2020	-48.58%	+317.97%
2019	+151.17%	+44.19%
2018	+42.96%	-19.21%
2017	+233.73%	+109.73%
2016	-64.58%	N/A
2015	+12.44%	N/A
2014	+1.37%	N/A

QURE vs APPN Drawdown Comparison

The maximum drawdown for QURE was -95.40%, occurring on Jul 8, 2024. This drawdown has not yet recovered.

The maximum drawdown for APPN was -92.04%, occurring on May 13, 2026. This drawdown has not yet recovered.

The current QURE drawdown is -67.82%. The current APPN drawdown is -89.49%.

Rank	QURE	APPN
#1	-95.40% Jun 21, 2019 - Jul 8, 2024	-92.04% Jan 27, 2021 - May 13, 2026
#2	-85.67% Apr 7, 2015 - May 24, 2018	-50.46% Feb 18, 2020 - Sep 29, 2020
#3	-52.19% Feb 26, 2014 - Jan 9, 2015	-46.61% Jun 18, 2018 - Aug 8, 2019
#4	-47.08% Sep 4, 2018 - Feb 25, 2019	-38.63% Aug 26, 2019 - Feb 18, 2020
#5	-25.51% Jun 20, 2018 - Aug 28, 2018	-37.05% Jan 5, 2018 - Jun 14, 2018
#6	-22.88% Mar 21, 2019 - Jun 4, 2019	-30.82% Sep 29, 2017 - Dec 26, 2017
#7	-18.54% Jan 14, 2015 - Feb 27, 2015	-29.72% Nov 27, 2020 - Jan 22, 2021
#8	-17.02% Mar 19, 2015 - Apr 6, 2015	-24.44% Oct 14, 2020 - Nov 6, 2020
#9	-12.68% Jun 7, 2019 - Jun 17, 2019	-17.57% Sep 11, 2017 - Sep 29, 2017
#10	-9.11% Jun 5, 2018 - Jun 18, 2018	-13.07% Jun 5, 2017 - Jul 12, 2017
#11	-8.21% Feb 5, 2014 - Feb 7, 2014	-10.81% Aug 8, 2017 - Aug 28, 2017
#12	-5.02% Mar 5, 2019 - Mar 7, 2019	-8.47% Jan 22, 2021 - Jan 26, 2021
#13	-4.73% Feb 25, 2019 - Mar 1, 2019	-8.06% Jul 20, 2017 - Aug 7, 2017
#14	-4.56% Jun 17, 2019 - Jun 21, 2019	-6.78% Nov 10, 2020 - Nov 13, 2020
#15	-3.88% Mar 11, 2015 - Mar 19, 2015	-6.31% Dec 28, 2017 - Jan 3, 2018