PVLA vs SION
Comparison between Palvella Therapeutics Inc (PVLA, Company) and Sionna Therapeutics Inc (SION, Company).
Both PVLA and SION are from the Healthcare sector.
PVLA vs SION - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap
Winner
PVLA
$2.04B
SION
$2.03B
Max Drawdown
Winner
PVLA
31.48%
SION
69.36%
Sharpe Ratio
Winner
PVLA
2.00
SION
1.42
5Y Beta
PVLA
1.03
Winner
SION
0.91
Industry
PVLA
Biotechnology
SION
Biotechnology
P/E Ratio
Winner
PVLA
-35.47
SION
-23.49
Debt to Equity
PVLA
0.00%
SION
0.00%
Free Cash Flow Yield
Winner
PVLA
-1.43%
SION
-3.55%
P/B Ratio
PVLA
8.89
Winner
SION
7.37
PVLA vs SION - Historical Returns
Returns include dividend reinvestment.
1M
Winner
PVLA
+20.66%
SION
+10.51%
3M
PVLA
+12.72%
Winner
SION
+14.89%
6M
Winner
PVLA
+67.88%
SION
+3.96%
1Y
Winner
PVLA
+272.64%
SION
+122.86%
Max(CAGR)
Winner
PVLA
+352.15%
SION
+47.67%
PVLA vs SION - Annual Returns (2024 - 2026)
Returns include dividend reinvestment.
| Year | PVLA | SION |
|---|---|---|
| 2026 | +42.81% | +12.37% |
| 2025 | +772.25% | +64.56% |
| 2024 | -6.47% | N/A |
PVLA vs SION Drawdown Comparison
The maximum drawdown for PVLA was -31.48%, occurring on Apr 10, 2025. Recovery took 87 trading sessions.
The maximum drawdown for SION was -69.36%, occurring on Apr 10, 2025. Recovery took 137 trading sessions.
The current PVLA drawdown is -8.93%. The current SION drawdown is -10.83%.
| Rank | PVLA | SION |
|---|---|---|
| #1 | -31.48% Mar 12, 2025 - Jul 17, 2025 | -69.36% Feb 7, 2025 - Aug 26, 2025 |
| #2 | -31.11% Feb 26, 2026 - Jun 29, 2026 | -27.07% May 11, 2026 - Jul 17, 2026 |
| #3 | -29.93% Dec 22, 2025 - Feb 24, 2026 | -23.74% Feb 3, 2026 - Apr 15, 2026 |
| #4 | -21.04% Jul 17, 2026 - Jul 20, 2026 | -19.06% Oct 21, 2025 - Nov 21, 2025 |
| #5 | -15.35% Jan 6, 2025 - Feb 5, 2025 | -18.12% Nov 24, 2025 - Feb 3, 2026 |
| #6 | -13.44% Nov 28, 2025 - Dec 22, 2025 | -17.26% Apr 16, 2026 - May 11, 2026 |
| #7 | -10.71% Jun 29, 2026 - Jul 17, 2026 | -15.94% Aug 28, 2025 - Sep 22, 2025 |
| #8 | -10.43% Feb 18, 2025 - Mar 5, 2025 | -10.83% Jul 17, 2026 - Jul 23, 2026 |
| #9 | -9.32% Oct 20, 2025 - Oct 30, 2025 | -5.53% Oct 3, 2025 - Oct 15, 2025 |
| #10 | -9.31% Dec 17, 2024 - Jan 3, 2025 | -3.56% Sep 29, 2025 - Oct 3, 2025 |
| #11 | -9.12% Aug 27, 2025 - Sep 9, 2025 | -2.41% Oct 16, 2025 - Oct 21, 2025 |
| #12 | -8.74% Sep 10, 2025 - Sep 29, 2025 | -0.36% Aug 26, 2025 - Aug 28, 2025 |
| #13 | -8.33% Jul 28, 2025 - Aug 8, 2025 | N/A |
| #14 | -6.61% Oct 8, 2025 - Oct 13, 2025 | N/A |
| #15 | -6.16% Aug 22, 2025 - Aug 26, 2025 | N/A |
Correlation
Correlation between PVLA and SION is 0.91 which considered as a very strong positive correlation - the stocks move almost identically together.
0.91
-101
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