PROF vs ACIU

Comparison between Profound Medical Corp (PROF, Company) and AC Immune SA (ACIU, Company).

Both PROF and ACIU are from the Healthcare sector.

5-Year PerformancePROF has outperformed ACIU, delivering a return of -15.2% compared to -17.3%

PROF vs ACIU - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PROF(COMPANY)	ACIU(COMPANY)
Market Cap	$253M	$254M
Max Drawdown	99.74%	92.33%
Sharpe Ratio	0.61	0.63
5Y Beta	0.78	1.02
Industry	Medical Devices	Biotechnology
P/E Ratio	-7.34	-4.72
Forward P/E	N/A	11.24
5Y EPS CAGR	N/A	-13.32%
Debt to Equity	18.10%	11.66%
Free Cash Flow Yield	-14.33%	-17.35%

Market Cap

PROF

$253M

Winner

ACIU

$254M

Max Drawdown

PROF

99.74%

Winner

ACIU

92.33%

Sharpe Ratio

PROF

0.61

Winner

ACIU

0.63

5Y Beta

Winner

PROF

0.78

ACIU

1.02

Industry

PROF

Medical Devices

ACIU

Biotechnology

P/E Ratio

Winner

PROF

-7.34

ACIU

-4.72

Forward P/E

PROF

N/A

ACIU

11.24

5Y EPS CAGR

PROF

N/A

ACIU

-13.32%

Debt to Equity

PROF

18.10%

Winner

ACIU

11.66%

Free Cash Flow Yield

Winner

PROF

-14.33%

ACIU

-17.35%

PROF vs ACIU - Historical Returns

Returns include dividend reinvestment.

Period	PROF	ACIU
1 month	-6.71%	+4.90%
3 months	-6.06%	-9.51%
6 months	+1.06%	-14.05%
1 year	+22.39%	+16.82%
5 years(CAGR)	-15.25%	-17.29%
10 years(CAGR)	-5.03%	-16.71%
Max(CAGR)	-4.07%	-16.71%

PROF

-6.71%

Winner

ACIU

+4.90%

Winner

PROF

-6.06%

ACIU

-9.51%

Winner

PROF

+1.06%

ACIU

-14.05%

Winner

PROF

+22.39%

ACIU

+16.82%

5Y(CAGR)

Winner

PROF

-15.25%

ACIU

-17.29%

10Y(CAGR)

Winner

PROF

-5.03%

ACIU

-16.71%

Max(CAGR)

Winner

PROF

-4.07%

ACIU

-16.71%

PROF vs ACIU - Annual Returns (2016 - 2026)

Returns include dividend reinvestment.

Year	PROF	ACIU
2026	-12.92%	-23.51%
2025	-0.38%	+10.18%
2024	-5.53%	-42.43%
2023	-23.17%	+126.24%
2022	-1.00%	-60.47%
2021	-48.86%	-6.95%
2020	+94.15%	-40.30%
2019	+124.66%	-16.63%
2018	-35.35%	-29.21%
2017	-17.98%	-1.61%
2016	-21.88%	-17.11%

PROF vs ACIU Drawdown Comparison

The maximum drawdown for PROF was -99.74%, occurring on Jul 19, 2017. Recovery took 639 trading sessions.

The maximum drawdown for ACIU was -92.33%, occurring on Apr 10, 2025. This drawdown has not yet recovered.

The current PROF drawdown is -76.25%. The current ACIU drawdown is -86.68%.

Rank	PROF	ACIU
#1	-99.74% Aug 18, 2016 - Sep 9, 2019	-92.33% Sep 28, 2016 - Apr 10, 2025
#2	-88.68% Feb 5, 2021 - Oct 26, 2022	N/A
#3	-65.10% Feb 7, 2020 - Nov 30, 2020	N/A
#4	-45.76% Sep 9, 2019 - Dec 26, 2019	N/A
#5	-17.15% Dec 26, 2019 - Jan 13, 2020	N/A
#6	-11.55% Dec 1, 2020 - Dec 21, 2020	N/A
#7	-10.22% Dec 22, 2020 - Jan 6, 2021	N/A
#8	-8.40% Jan 16, 2020 - Jan 28, 2020	N/A
#9	-7.59% Jul 6, 2016 - Aug 10, 2016	N/A
#10	-7.55% Jan 26, 2021 - Feb 4, 2021	N/A
#11	-5.31% Jan 15, 2021 - Jan 20, 2021	N/A
#12	-3.68% Jan 11, 2021 - Jan 15, 2021	N/A
#13	-2.55% Jan 13, 2020 - Jan 15, 2020	N/A
#14	-1.63% Jan 21, 2021 - Jan 25, 2021	N/A