PRME vs SLN
Comparison between Prime Medicine Inc (PRME, Company) and Silence Therapeutics Plc (SLN, Company).
Both PRME and SLN are from the Healthcare sector.
PRME vs SLN - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap
PRME
$558M
Winner
SLN
$559M
Max Drawdown
PRME
94.55%
Winner
SLN
92.31%
Sharpe Ratio
PRME
-0.03
Winner
SLN
1.16
5Y Beta
PRME
2.10
Winner
SLN
0.90
Industry
PRME
Biotechnology
SLN
Biotechnology
P/E Ratio
PRME
-2.58
Winner
SLN
-7.45
PEG Ratio
PRME
N/A
SLN
-1.69
Debt to Equity
PRME
0.00%
SLN
0.00%
Free Cash Flow Yield
PRME
-28.44%
Winner
SLN
-11.74%
PRME vs SLN - Historical Returns
Returns include dividend reinvestment.
1M
PRME
-8.33%
Winner
SLN
+57.50%
3M
PRME
-22.66%
Winner
SLN
+46.05%
6M
PRME
-32.96%
Winner
SLN
+101.94%
1Y
PRME
-35.99%
Winner
SLN
+86.18%
5Y(CAGR)
PRME
N/A
SLN
-14.47%
Max(CAGR)
PRME
-35.44%
Winner
SLN
-8.67%
PRME vs SLN - Annual Returns (2020 - 2026)
Returns include dividend reinvestment.
| Year | PRME | SLN |
|---|---|---|
| 2026 | -15.86% | +86.18% |
| 2025 | +16.05% | -15.44% |
| 2024 | -66.67% | -62.91% |
| 2023 | -49.49% | +18.24% |
| 2022 | +20.88% | -36.17% |
| 2021 | N/A | -0.46% |
| 2020 | N/A | +12.82% |
PRME vs SLN Drawdown Comparison
The maximum drawdown for PRME was -94.55%, occurring on Apr 8, 2025. This drawdown has not yet recovered.
The maximum drawdown for SLN was -92.31%, occurring on Apr 9, 2025. This drawdown has not yet recovered.
The current PRME drawdown is -85.94%. The current SLN drawdown is -59.61%.
| Rank | PRME | SLN |
|---|---|---|
| #1 | -94.55% Nov 1, 2022 - Apr 8, 2025 | -92.31% Jun 28, 2021 - Apr 9, 2025 |
| #2 | -3.55% Oct 21, 2022 - Oct 25, 2022 | -23.08% Sep 8, 2020 - Nov 9, 2020 |
| #3 | N/A | -20.24% Feb 22, 2021 - Jun 11, 2021 |
| #4 | N/A | -16.46% Nov 9, 2020 - Dec 23, 2020 |
| #5 | N/A | -9.17% Jan 4, 2021 - Jan 22, 2021 |
| #6 | N/A | -8.45% Jun 11, 2021 - Jun 28, 2021 |
| #7 | N/A | -4.59% Jan 27, 2021 - Feb 17, 2021 |
| #8 | N/A | -2.85% Jan 22, 2021 - Jan 26, 2021 |
| #9 | N/A | -2.61% Feb 18, 2021 - Feb 22, 2021 |
Correlation
Correlation between PRME and SLN is 0.16 which considered as a very weak or no correlation - the stocks move independently of each other.
0.16
-101
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