PRME vs CASS

Comparison between Prime Medicine Inc (PRME, Company) and Cass Information Systems Inc (CASS, Company).

PRME is from the Healthcare sector, while CASS is from the Industrials sector.

PRME vs CASS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PRME(COMPANY)	CASS(COMPANY)
Market Cap	$596M	$595M
Max Drawdown	94.55%	52.54%
Sharpe Ratio	1.29	0.60
5Y Beta	2.13	0.71
Industry	Biotechnology	Specialty Business Services
P/E Ratio	-2.75	17.25
Forward P/E	N/A	18.62
PEG Ratio	N/A	0.24
Dividend Yield	N/A	2.68%
5Y Dividends CAGR	N/A	14.15%
5Y EPS CAGR	N/A	8.30%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-26.63%	4.27%
P/S Ratio	158.95	2.83
P/B Ratio	7.99	2.45

Market Cap

Winner

PRME

$596M

CASS

$595M

Max Drawdown

PRME

94.55%

Winner

CASS

52.54%

Sharpe Ratio

Winner

PRME

1.29

CASS

0.60

5Y Beta

PRME

2.13

Winner

CASS

0.71

Industry

PRME

Biotechnology

CASS

Specialty Business Services

P/E Ratio

Winner

PRME

-2.75

CASS

17.25

Forward P/E

PRME

N/A

CASS

18.62

PEG Ratio

PRME

N/A

CASS

0.24

Dividend Yield

PRME

N/A

CASS

2.68%

5Y Dividends CAGR

PRME

N/A

CASS

14.15%

5Y EPS CAGR

PRME

N/A

CASS

8.30%

Debt to Equity

PRME

0.00%

CASS

0.00%

Free Cash Flow Yield

PRME

-26.63%

Winner

CASS

4.27%

P/S Ratio

PRME

158.95

Winner

CASS

2.83

P/B Ratio

PRME

7.99

Winner

CASS

2.45

PRME vs CASS - Historical Returns

Returns include dividend reinvestment.

Period	PRME	CASS
1 month	-9.73%	+0.73%
3 months	-22.14%	+5.21%
6 months	-18.18%	+10.95%
1 year	+125.00%	+16.22%
5 years(CAGR)	N/A	+3.47%
10 years(CAGR)	N/A	+4.77%
Max(CAGR)	-35.93%	+11.16%

PRME

-9.73%

Winner

CASS

+0.73%

PRME

-22.14%

Winner

CASS

+5.21%

PRME

-18.18%

Winner

CASS

+10.95%

Winner

PRME

+125.00%

CASS

+16.22%

5Y(CAGR)

PRME

N/A

CASS

+3.47%

10Y(CAGR)

PRME

N/A

CASS

+4.77%

Max(CAGR)

PRME

-35.93%

Winner

CASS

+11.16%

PRME vs CASS - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	PRME	CASS
2026	-13.31%	+17.94%
2025	+16.05%	+6.57%
2024	-66.67%	-7.38%
2023	-49.49%	+2.29%
2022	+20.88%	+18.15%
2021	N/A	+5.18%
2020	N/A	-30.33%
2019	N/A	+11.33%
2018	N/A	+10.24%
2017	N/A	-11.12%
2016	N/A	+51.44%
2015	N/A	+4.32%
2014	N/A	-17.09%
2013	N/A	+57.37%
2012	N/A	+26.43%
2011	N/A	+5.82%
2010	N/A	+25.49%
2009	N/A	+1.83%
2008	N/A	-6.88%
2007	N/A	+8.87%
2006	N/A	+70.14%
2005	N/A	+43.38%
2004	N/A	+18.58%
2003	N/A	+38.54%
2002	N/A	+4.83%
2001	N/A	+43.38%
2000	N/A	-8.32%
1999	N/A	-8.99%

PRME vs CASS Drawdown Comparison

The maximum drawdown for PRME was -94.55%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The maximum drawdown for CASS was -50.87%, occurring on Mar 18, 2020. This drawdown has not yet recovered.

The current PRME drawdown is -85.51%. The current CASS drawdown is -6.14%.

Rank	PRME	CASS
#1	-94.55% Nov 1, 2022 - Apr 8, 2025	-50.87% Jun 22, 2018 - Mar 18, 2020
#2	-3.55% Oct 21, 2022 - Oct 25, 2022	-40.38% Dec 30, 2013 - Nov 15, 2016
#3	N/A	-38.92% Aug 11, 2008 - Dec 6, 2010
#4	N/A	-30.13% Dec 10, 2007 - Aug 11, 2008
#5	N/A	-26.39% Jan 25, 2001 - Oct 5, 2001
#6	N/A	-24.26% Nov 9, 1999 - Jan 24, 2001
#7	N/A	-24.00% Apr 6, 2011 - Oct 27, 2011
#8	N/A	-22.87% Jun 28, 2006 - Sep 1, 2006
#9	N/A	-21.79% Sep 16, 2005 - Apr 19, 2006
#10	N/A	-20.02% Dec 27, 2016 - Jun 14, 2018
#11	N/A	-20.00% May 6, 2003 - Sep 10, 2003
#12	N/A	-18.06% Nov 15, 2006 - Nov 29, 2007
#13	N/A	-17.84% Nov 3, 2011 - Dec 6, 2011
#14	N/A	-17.34% Aug 14, 2013 - Nov 27, 2013
#15	N/A	-15.90% Sep 5, 2006 - Oct 27, 2006

Correlation

Correlation between PRME and CASS is -0.34 which considered as a weak negative correlation - the stocks show a slight tendency to move in opposite directions.

-0.34

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