PRME vs AKUS

Comparison between Prime Medicine Inc (PRME, Company) and Akouos Inc (AKUS, Company).

PRME vs AKUS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PRME(COMPANY)	AKUS(COMPANY)
Market Cap	$489M	$490M
Max Drawdown	94.55%	90.86%
Sharpe Ratio	1.05	0.86
5Y Beta	2.13	N/A
Industry	Biotechnology	N/A
P/E Ratio	-2.26	-5.30
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-32.43%	-15.58%
P/S Ratio	121.34	N/A
P/B Ratio	6.38	2.71

Market Cap

PRME

$489M

Winner

AKUS

$490M

Max Drawdown

PRME

94.55%

Winner

AKUS

90.86%

Sharpe Ratio

Winner

PRME

1.05

AKUS

0.86

5Y Beta

PRME

2.13

AKUS

N/A

Industry

PRME

Biotechnology

AKUS

N/A

P/E Ratio

PRME

-2.26

Winner

AKUS

-5.30

Debt to Equity

PRME

0.00%

AKUS

0.00%

Free Cash Flow Yield

PRME

-32.43%

Winner

AKUS

-15.58%

P/S Ratio

PRME

121.34

AKUS

N/A

P/B Ratio

PRME

6.38

Winner

AKUS

2.71

PRME vs AKUS - Historical Returns

Returns include dividend reinvestment.

Period	PRME	AKUS
1 month	-15.91%	+0.00%
3 months	-25.60%	+95.44%
6 months	-32.32%	+327.33%
1 year	+90.07%	+46.37%
Max(CAGR)	-37.48%	-18.12%

PRME

-15.91%

Winner

AKUS

+0.00%

PRME

-25.60%

Winner

AKUS

+95.44%

PRME

-32.32%

Winner

AKUS

+327.33%

Winner

PRME

+90.07%

AKUS

+46.37%

Max(CAGR)

PRME

-37.48%

Winner

AKUS

-18.12%

PRME vs AKUS - Annual Returns (2020 - 2026)

Returns include dividend reinvestment.

Year	PRME	AKUS
2026	-21.39%	N/A
2025	+16.05%	N/A
2024	-66.67%	N/A
2023	-49.49%	+0.00%
2022	+20.88%	+46.37%
2021	N/A	-56.25%
2020	N/A	-9.86%

PRME vs AKUS Drawdown Comparison

The maximum drawdown for PRME was -94.55%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The maximum drawdown for AKUS was -90.86%, occurring on May 25, 2022. This drawdown has not yet recovered.

The current PRME drawdown is -86.86%. The current AKUS drawdown is -50.63%.

Rank	PRME	AKUS
#1	-94.55% Nov 1, 2022 - Apr 8, 2025	-90.86% Sep 14, 2020 - May 25, 2022
#2	-3.55% Oct 21, 2022 - Oct 25, 2022	-14.22% Jun 30, 2020 - Aug 28, 2020
#3	N/A	-7.97% Sep 2, 2020 - Sep 8, 2020
#4	N/A	-4.37% Sep 9, 2020 - Sep 14, 2020
#5	N/A	-0.80% Aug 28, 2020 - Sep 1, 2020

Correlation

Correlation between PRME and AKUS is -0.66 which considered as a moderate negative correlation - the stocks show some tendency to move in opposite directions.

-0.66

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