PRLD vs ORGO

Comparison between Prelude Therapeutics Inc (PRLD, Company) and Organogenesis Holdings Inc - Class A (ORGO, Company).

Both PRLD and ORGO are from the Healthcare sector.

5-Year PerformanceORGO has outperformed PRLD, delivering a return of -32.3% compared to -34.8%

PRLD vs ORGO - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PRLD(COMPANY)	ORGO(COMPANY)
Market Cap	$343M	$342M
Max Drawdown	99.33%	98.74%
Sharpe Ratio	1.45	0.14
5Y Beta	1.84	1.97
Industry	Biotechnology	Drug Manufacturers - Specialty & Generic
P/E Ratio	-3.89	98.45
Forward P/E	N/A	12.67
5Y EPS CAGR	N/A	-40.50%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-12.75%	4.99%
P/S Ratio	18.67	0.64
P/B Ratio	5.22	1.35

Market Cap

Winner

PRLD

$343M

ORGO

$342M

Max Drawdown

PRLD

99.33%

Winner

ORGO

98.74%

Sharpe Ratio

Winner

PRLD

1.45

ORGO

0.14

5Y Beta

Winner

PRLD

1.84

ORGO

1.97

Industry

PRLD

Biotechnology

ORGO

Drug Manufacturers - Specialty & Generic

P/E Ratio

Winner

PRLD

-3.89

ORGO

98.45

Forward P/E

PRLD

N/A

ORGO

12.67

5Y EPS CAGR

PRLD

N/A

ORGO

-40.50%

Debt to Equity

PRLD

0.00%

ORGO

0.00%

Free Cash Flow Yield

PRLD

-12.75%

Winner

ORGO

4.99%

P/S Ratio

PRLD

18.67

Winner

ORGO

0.64

P/B Ratio

PRLD

5.22

Winner

ORGO

1.35

PRLD vs ORGO - Historical Returns

Returns include dividend reinvestment.

Period	PRLD	ORGO
1 month	-22.78%	-8.98%
3 months	+39.16%	-18.82%
6 months	+165.22%	-53.31%
1 year	+291.32%	-17.08%
5 years(CAGR)	-34.79%	-32.31%
10 years(CAGR)	N/A	-14.11%
Max(CAGR)	-29.26%	-14.11%

PRLD

-22.78%

Winner

ORGO

-8.98%

Winner

PRLD

+39.16%

ORGO

-18.82%

Winner

PRLD

+165.22%

ORGO

-53.31%

Winner

PRLD

+291.32%

ORGO

-17.08%

5Y(CAGR)

PRLD

-34.79%

Winner

ORGO

-32.31%

10Y(CAGR)

PRLD

N/A

ORGO

-14.11%

Max(CAGR)

PRLD

-29.26%

Winner

ORGO

-14.11%

PRLD vs ORGO - Annual Returns (2017 - 2026)

Returns include dividend reinvestment.

Year	PRLD	ORGO
2026	+34.07%	-49.73%
2025	+132.00%	+70.96%
2024	-68.67%	-21.57%
2023	-14.94%	+56.70%
2022	-54.31%	-71.89%
2021	-81.54%	+17.86%
2020	+173.09%	+57.53%
2019	N/A	-52.61%
2018	N/A	+2.42%
2017	N/A	+1.74%

PRLD vs ORGO Drawdown Comparison

The maximum drawdown for PRLD was -99.33%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The maximum drawdown for ORGO was -98.74%, occurring on Mar 24, 2023. This drawdown has not yet recovered.

The current PRLD drawdown is -96.01%. The current ORGO drawdown is -98.45%.

Rank	PRLD	ORGO
#1	-99.33% Feb 10, 2021 - Apr 8, 2025	-98.74% Jan 11, 2019 - Mar 24, 2023
#2	-36.23% Oct 7, 2020 - Nov 5, 2020	-6.43% Oct 8, 2018 - Oct 26, 2018
#3	-32.75% Dec 24, 2020 - Feb 9, 2021	-5.97% Oct 24, 2017 - Jan 25, 2018
#4	-17.47% Nov 19, 2020 - Dec 10, 2020	-5.14% Oct 26, 2018 - Jan 8, 2019
#5	-14.10% Nov 5, 2020 - Nov 13, 2020	-1.79% Jan 25, 2018 - Jun 19, 2018
#6	-3.78% Dec 14, 2020 - Dec 17, 2020	-1.61% Feb 17, 2017 - Aug 21, 2017
#7	-1.46% Oct 1, 2020 - Oct 5, 2020	-0.99% Sep 13, 2018 - Oct 2, 2018
#8	-0.47% Dec 17, 2020 - Dec 21, 2020	-0.69% Jun 19, 2018 - Jul 31, 2018
#9	N/A	-0.49% Aug 8, 2018 - Sep 13, 2018
#10	N/A	-0.40% Aug 23, 2017 - Oct 20, 2017
#11	N/A	-0.29% Oct 2, 2018 - Oct 8, 2018
#12	N/A	-0.10% Feb 15, 2017 - Feb 17, 2017