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PLRX vs SPRB

Comparison between Pliant Therapeutics Inc (PLRX, Company) and Spruce Biosciences Inc (SPRB, Company).

Both PLRX and SPRB are from the Healthcare sector.

5-Year PerformanceSPRB has outperformed PLRX, delivering a return of -42.5% compared to -46.8%

PLRX vs SPRB - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap
Winner
PLRX
$68M
SPRB
$68M
Max Drawdown
Winner
PLRX
97.34%
SPRB
99.81%
Sharpe Ratio
PLRX
-0.28
Winner
SPRB
0.96
5Y Beta
Winner
PLRX
1.21
SPRB
1.61
Industry
PLRX
Biotechnology
SPRB
Biotechnology
P/E Ratio
PLRX
-0.60
Winner
SPRB
-1.31
5Y EPS CAGR
Winner
PLRX
-2.79%
SPRB
-12.70%
Debt to Equity
Winner
PLRX
0.00%
SPRB
18.66%
Free Cash Flow Yield
PLRX
N/A
SPRB
-43.18%
P/S Ratio
PLRX
N/A
SPRB
49.19
P/B Ratio
PLRX
N/A
SPRB
3.85

PLRX vs SPRB - Historical Returns

Returns include dividend reinvestment.

1M
Winner
PLRX
-6.90%
SPRB
-13.71%
3M
Winner
PLRX
-14.29%
SPRB
-16.70%
6M
Winner
PLRX
-16.92%
SPRB
-44.81%
1Y
PLRX
-31.65%
Winner
SPRB
+385.72%
5Y(CAGR)
PLRX
-46.83%
Winner
SPRB
-42.51%
Max(CAGR)
Winner
PLRX
-38.49%
SPRB
-43.90%

PLRX vs SPRB - Annual Returns (2020 - 2026)

Returns include dividend reinvestment.

YearPLRXSPRB
2026-13.60%-50.40%
2025-90.81%+176.94%
2024-26.67%-85.81%
2023-4.68%+154.78%
2022+37.09%-76.09%
2021-44.94%-80.40%
2020+6.67%+43.00%

PLRX vs SPRB Drawdown Comparison

The maximum drawdown for PLRX was -97.34%, occurring on Jul 20, 2026. This drawdown has not yet recovered.

The maximum drawdown for SPRB was -99.81%, occurring on Jun 9, 2025. This drawdown has not yet recovered.

The current PLRX drawdown is -97.32%. The current SPRB drawdown is -98.15%.

RankPLRXSPRB
#1-97.34%
Mar 25, 2021 - Jul 20, 2026
-99.81%
Nov 27, 2020 - Jun 9, 2025
#2-43.59%
Jun 29, 2020 - Feb 24, 2021
-20.38%
Oct 29, 2020 - Nov 13, 2020
#3-21.34%
Feb 24, 2021 - Mar 25, 2021
-13.84%
Oct 14, 2020 - Oct 23, 2020
#4-5.82%
Jun 4, 2020 - Jun 15, 2020
-2.56%
Nov 20, 2020 - Nov 27, 2020
#5-2.53%
Jun 15, 2020 - Jun 17, 2020
-2.16%
Nov 16, 2020 - Nov 18, 2020
#6-0.04%
Jun 19, 2020 - Jun 23, 2020
N/A

Correlation

Correlation between PLRX and SPRB is 0.60 which considered as a moderate positive correlation - the stocks show some tendency to move together.

0.60
-101

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