PCVX vs CBSH

Comparison between Vaxcyte Inc (PCVX, Company) and Commerce Bancshares Inc (CBSH, Company).

PCVX is from the Healthcare sector, while CBSH is from the Financial Services sector.

5-Year PerformancePCVX has outperformed CBSH, delivering a return of +17.7% compared to +3.6%

PCVX vs CBSH - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PCVX(COMPANY)	CBSH(COMPANY)
Market Cap	$8.64B	$8.61B
Max Drawdown	76.22%	45.45%
Sharpe Ratio	1.66	0.21
5Y Beta	0.72	0.69
Industry	Biotechnology	Banks - Regional
P/E Ratio	-7.74	14.31
Forward P/E	N/A	13.23
PEG Ratio	-0.10	2.06
Dividend Yield	N/A	1.83%
5Y Dividends CAGR	N/A	5.42%
5Y EPS CAGR	35.48%	-0.26%
Debt to Equity	0.00%	56.33%
Free Cash Flow Yield	-10.35%	13.91%
P/S Ratio	N/A	4.65
P/B Ratio	N/A	1.96

Market Cap

Winner

PCVX

$8.64B

CBSH

$8.61B

Max Drawdown

PCVX

76.22%

Winner

CBSH

45.45%

Sharpe Ratio

Winner

PCVX

1.66

CBSH

0.21

5Y Beta

PCVX

0.72

Winner

CBSH

0.69

Industry

PCVX

Biotechnology

CBSH

Banks - Regional

P/E Ratio

Winner

PCVX

-7.74

CBSH

14.31

Forward P/E

PCVX

N/A

CBSH

13.23

PEG Ratio

Winner

PCVX

-0.10

CBSH

2.06

Dividend Yield

PCVX

N/A

CBSH

1.83%

5Y Dividends CAGR

PCVX

N/A

CBSH

5.42%

5Y EPS CAGR

Winner

PCVX

35.48%

CBSH

-0.26%

Debt to Equity

Winner

PCVX

0.00%

CBSH

56.33%

Free Cash Flow Yield

PCVX

-10.35%

Winner

CBSH

13.91%

P/S Ratio

PCVX

N/A

CBSH

4.65

P/B Ratio

PCVX

N/A

CBSH

1.96

PCVX vs CBSH - Historical Returns

Returns include dividend reinvestment.

Period	PCVX	CBSH
1 month	+3.21%	+2.58%
3 months	+8.50%	+19.85%
6 months	+8.80%	+13.14%
1 year	+86.56%	+3.66%
5 years(CAGR)	+17.73%	+3.60%
10 years(CAGR)	N/A	+9.38%
Max(CAGR)	+14.06%	+8.73%

Winner

PCVX

+3.21%

CBSH

+2.58%

PCVX

+8.50%

Winner

CBSH

+19.85%

PCVX

+8.80%

Winner

CBSH

+13.14%

Winner

PCVX

+86.56%

CBSH

+3.66%

5Y(CAGR)

Winner

PCVX

+17.73%

CBSH

+3.60%

10Y(CAGR)

PCVX

N/A

CBSH

+9.38%

Max(CAGR)

Winner

PCVX

+14.06%

CBSH

+8.73%

PCVX vs CBSH - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	PCVX	CBSH
2026	+26.69%	+16.08%
2025	-44.61%	-9.32%
2024	+30.06%	+22.87%
2023	+33.05%	-15.35%
2022	+82.46%	+4.50%
2021	-11.92%	+10.82%
2020	+1.61%	+3.68%
2019	N/A	+28.71%
2018	N/A	+7.33%
2017	N/A	+3.37%
2016	N/A	+50.76%
2015	N/A	+5.40%
2014	N/A	+5.74%
2013	N/A	+32.56%
2012	N/A	+1.71%
2011	N/A	+1.13%
2010	N/A	+5.93%
2009	N/A	-4.00%
2008	N/A	+7.16%
2007	N/A	-5.15%
2006	N/A	+0.47%
2005	N/A	+13.97%
2004	N/A	+11.61%
2003	N/A	+31.38%
2002	N/A	+9.37%
2001	N/A	+3.26%
2000	N/A	+38.21%
1999	N/A	-9.94%

PCVX vs CBSH Drawdown Comparison

The maximum drawdown for PCVX was -76.22%, occurring on Apr 10, 2025. This drawdown has not yet recovered.

The maximum drawdown for CBSH was -44.65%, occurring on Mar 9, 2009. Recovery took 996 trading sessions.

The current PCVX drawdown is -50.09%. The current CBSH drawdown is -8.04%.

Rank	PCVX	CBSH
#1	-76.22% Oct 16, 2024 - Apr 10, 2025	-44.65% Oct 1, 2008 - Sep 13, 2012
#2	-70.31% Sep 23, 2020 - Dec 6, 2023	-38.21% May 6, 2021 - Nov 6, 2024
#3	-33.91% Aug 20, 2020 - Sep 22, 2020	-34.85% Feb 11, 2020 - Nov 16, 2020
#4	-25.90% Feb 27, 2024 - Jul 11, 2024	-31.20% Nov 9, 1999 - Nov 30, 2000
#5	-25.25% Jun 19, 2020 - Aug 10, 2020	-27.59% Nov 25, 2024 - Mar 12, 2026
#6	-17.19% Jul 24, 2024 - Sep 3, 2024	-24.70% Apr 17, 2002 - Jul 31, 2003
#7	-7.39% Sep 19, 2024 - Oct 16, 2024	-22.92% Feb 22, 2007 - Sep 18, 2008
#8	-7.07% Jan 4, 2024 - Jan 23, 2024	-22.73% Feb 12, 2001 - Feb 11, 2002
#9	-5.48% Jul 15, 2024 - Jul 24, 2024	-21.55% Aug 21, 2018 - Nov 27, 2019
#10	-5.43% Feb 12, 2024 - Feb 23, 2024	-17.95% Dec 1, 2015 - Apr 14, 2016
#11	-3.10% Dec 19, 2023 - Dec 26, 2023	-12.37% Jul 3, 2014 - May 19, 2015
#12	-2.90% Jan 23, 2024 - Jan 29, 2024	-12.34% Sep 14, 2012 - Feb 13, 2013
#13	-2.74% Feb 1, 2024 - Feb 12, 2024	-12.33% Sep 19, 2008 - Oct 1, 2008
#14	-2.66% Aug 14, 2020 - Aug 19, 2020	-12.31% Mar 1, 2017 - Nov 29, 2017
#15	-2.65% Aug 10, 2020 - Aug 12, 2020	-11.72% Jul 20, 2015 - Nov 6, 2015