PBYI vs MTLS

Comparison between Puma Biotechnology Inc (PBYI, Company) and Materialise Nv (MTLS, Company).

PBYI is from the Healthcare sector, while MTLS is from the Technology sector.

5-Year PerformancePBYI has outperformed MTLS, delivering a return of -8.4% compared to -21.9%

PBYI vs MTLS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PBYI(COMPANY)	MTLS(COMPANY)
Market Cap	$357M	$386M
Max Drawdown	99.40%	94.84%
Sharpe Ratio	1.30	0.45
5Y Beta	0.83	1.19
Industry	Biotechnology	Software - Application
P/E Ratio	14.45	31.82
Forward P/E	3.46	625.00
PEG Ratio	0.03	1.46
Debt to Equity	8.79%	23.52%
Free Cash Flow Yield	14.99%	2.04%
P/S Ratio	1.62	1.44
P/B Ratio	2.78	1.31

Market Cap

PBYI

$357M

Winner

MTLS

$386M

Max Drawdown

PBYI

99.40%

Winner

MTLS

94.84%

Sharpe Ratio

Winner

PBYI

1.30

MTLS

0.45

5Y Beta

Winner

PBYI

0.83

MTLS

1.19

Industry

PBYI

Biotechnology

MTLS

Software - Application

P/E Ratio

Winner

PBYI

14.45

MTLS

31.82

Forward P/E

Winner

PBYI

3.46

MTLS

625.00

PEG Ratio

Winner

PBYI

0.03

MTLS

1.46

Debt to Equity

Winner

PBYI

8.79%

MTLS

23.52%

Free Cash Flow Yield

Winner

PBYI

14.99%

MTLS

2.04%

P/S Ratio

PBYI

1.62

Winner

MTLS

1.44

P/B Ratio

PBYI

2.78

Winner

MTLS

1.31

PBYI vs MTLS - Historical Returns

Returns include dividend reinvestment.

Period	PBYI	MTLS
1 month	+3.53%	+14.83%
3 months	+24.66%	+22.88%
6 months	+25.09%	+17.25%
1 year	+105.90%	+19.57%
5 years(CAGR)	-8.37%	-21.93%
10 years(CAGR)	-13.95%	-0.37%
Max(CAGR)	-4.48%	-4.50%

PBYI

+3.53%

Winner

MTLS

+14.83%

Winner

PBYI

+24.66%

MTLS

+22.88%

Winner

PBYI

+25.09%

MTLS

+17.25%

Winner

PBYI

+105.90%

MTLS

+19.57%

5Y(CAGR)

Winner

PBYI

-8.37%

MTLS

-21.93%

10Y(CAGR)

PBYI

-13.95%

Winner

MTLS

-0.37%

Max(CAGR)

Winner

PBYI

-4.48%

MTLS

-4.50%

PBYI vs MTLS - Annual Returns (2012 - 2026)

Returns include dividend reinvestment.

Year	PBYI	MTLS
2026	+27.04%	+22.20%
2025	+90.71%	-21.72%
2024	-32.60%	+11.92%
2023	+4.84%	-23.93%
2022	+32.60%	-64.07%
2021	-70.57%	-56.24%
2020	+21.71%	+191.30%
2019	-59.64%	-8.72%
2018	-78.04%	+61.53%
2017	+213.81%	+65.49%
2016	-58.25%	+9.09%
2015	-58.71%	-26.23%
2014	+85.45%	-17.58%
2013	+444.61%	N/A
2012	+33.93%	N/A

PBYI vs MTLS Drawdown Comparison

The maximum drawdown for PBYI was -99.40%, occurring on May 11, 2022. This drawdown has not yet recovered.

The maximum drawdown for MTLS was -94.84%, occurring on Apr 7, 2025. This drawdown has not yet recovered.

The current PBYI drawdown is -97.34%. The current MTLS drawdown is -91.74%.

Rank	PBYI	MTLS
#1	-99.40% Sep 18, 2014 - May 11, 2022	-94.84% Feb 9, 2021 - Apr 7, 2025
#2	-60.70% Jan 21, 2014 - Jul 23, 2014	-62.79% Jul 7, 2014 - Jul 25, 2017
#3	-39.73% Sep 9, 2013 - Dec 5, 2013	-44.89% Jan 9, 2019 - Apr 29, 2020
#4	-23.10% Jul 23, 2014 - Aug 18, 2014	-37.29% Oct 14, 2020 - Dec 22, 2020
#5	-21.43% Apr 24, 2012 - Aug 20, 2012	-30.33% Oct 16, 2017 - Dec 18, 2018
#6	-19.73% Oct 23, 2012 - Jan 15, 2013	-28.50% Sep 2, 2020 - Oct 9, 2020
#7	-19.28% Apr 17, 2013 - May 16, 2013	-23.77% Jun 10, 2020 - Jul 21, 2020
#8	-18.00% Jul 22, 2013 - Sep 9, 2013	-21.51% Jul 21, 2020 - Aug 21, 2020
#9	-15.23% Jan 24, 2013 - Mar 6, 2013	-18.53% Jul 25, 2017 - Oct 5, 2017
#10	-14.09% May 29, 2013 - Jun 19, 2013	-15.91% Apr 29, 2020 - May 20, 2020
#11	-10.14% Oct 8, 2012 - Oct 19, 2012	-15.36% Dec 23, 2020 - Jan 6, 2021
#12	-9.33% Aug 18, 2014 - Aug 26, 2014	-12.51% Jan 19, 2021 - Feb 8, 2021
#13	-8.78% Dec 9, 2013 - Dec 16, 2013	-8.93% Jan 8, 2021 - Jan 14, 2021
#14	-8.36% Mar 28, 2013 - Apr 15, 2013	-8.63% Jan 14, 2021 - Jan 19, 2021
#15	-7.30% Dec 24, 2013 - Jan 9, 2014	-7.28% May 26, 2020 - Jun 1, 2020