PALI vs ORGO

Comparison between Palisade Bio Inc (PALI, Company) and Organogenesis Holdings Inc - Class A (ORGO, Company).

Both PALI and ORGO are from the Healthcare sector.

5-Year PerformanceORGO has outperformed PALI, delivering a return of -30.2% compared to -76.1%

PALI vs ORGO - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PALI(COMPANY)	ORGO(COMPANY)
Market Cap	$318M	$318M
Max Drawdown	100.00%	98.74%
Sharpe Ratio	0.99	-0.64
5Y Beta	0.00	1.94
Industry	Biotechnology	Drug Manufacturers - Specialty & Generic
P/E Ratio	-10.99	91.41
Forward P/E	N/A	12.67
5Y EPS CAGR	N/A	-40.50%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-3.90%	5.37%
P/S Ratio	11.78	0.62
P/B Ratio	2.61	1.42

Market Cap

Winner

PALI

$318M

ORGO

$318M

Max Drawdown

PALI

100.00%

Winner

ORGO

98.74%

Sharpe Ratio

Winner

PALI

0.99

ORGO

-0.64

5Y Beta

Winner

PALI

0.00

ORGO

1.94

Industry

PALI

Biotechnology

ORGO

Drug Manufacturers - Specialty & Generic

P/E Ratio

Winner

PALI

-10.99

ORGO

91.41

Forward P/E

PALI

N/A

ORGO

12.67

5Y EPS CAGR

PALI

N/A

ORGO

-40.50%

Debt to Equity

PALI

0.00%

ORGO

0.00%

Free Cash Flow Yield

PALI

-3.90%

Winner

ORGO

5.37%

P/S Ratio

PALI

11.78

Winner

ORGO

0.62

P/B Ratio

PALI

2.61

Winner

ORGO

1.42

PALI vs ORGO - Historical Returns

Returns include dividend reinvestment.

Period	PALI	ORGO
1 month	-9.42%	+4.55%
3 months	+3.59%	+5.42%
6 months	+20.96%	-34.96%
1 year	+62.90%	-49.60%
5 years(CAGR)	-76.14%	-30.25%
10 years(CAGR)	-69.46%	-13.16%
Max(CAGR)	-50.95%	-13.16%

PALI

-9.42%

Winner

ORGO

+4.55%

PALI

+3.59%

Winner

ORGO

+5.42%

Winner

PALI

+20.96%

ORGO

-34.96%

Winner

PALI

+62.90%

ORGO

-49.60%

5Y(CAGR)

PALI

-76.14%

Winner

ORGO

-30.25%

10Y(CAGR)

PALI

-69.46%

Winner

ORGO

-13.16%

Max(CAGR)

PALI

-50.95%

Winner

ORGO

-13.16%

PALI vs ORGO - Annual Returns (2006 - 2026)

Returns include dividend reinvestment.

Year	PALI	ORGO
2026	-19.20%	-45.42%
2025	+26.34%	+70.96%
2024	-81.00%	-21.57%
2023	-84.55%	+56.70%
2022	-93.11%	-71.89%
2021	-78.96%	+17.86%
2020	-20.00%	+57.53%
2019	-84.99%	-52.61%
2018	-84.58%	+2.42%
2017	-57.46%	+1.74%
2016	-73.46%	N/A
2015	-63.35%	N/A
2014	-13.92%	N/A
2013	+140.50%	N/A
2012	+9.00%	N/A
2011	-55.53%	N/A
2010	+14.59%	N/A
2009	+7.19%	N/A
2008	-55.00%	N/A
2007	+48.02%	N/A
2006	+50.00%	N/A

PALI vs ORGO Drawdown Comparison

The maximum drawdown for PALI was -100.00%, occurring on Sep 10, 2025. This drawdown has not yet recovered.

The maximum drawdown for ORGO was -98.74%, occurring on Mar 24, 2023. This drawdown has not yet recovered.

The current PALI drawdown is -100.00%. The current ORGO drawdown is -98.31%.

Rank	PALI	ORGO
#1	-100.00% Apr 9, 2014 - Sep 10, 2025	-98.74% Jan 11, 2019 - Mar 24, 2023
#2	-88.86% Apr 26, 2007 - Mar 17, 2014	-6.43% Oct 8, 2018 - Oct 26, 2018
#3	-24.62% Jan 10, 2007 - Mar 26, 2007	-5.97% Oct 24, 2017 - Jan 25, 2018
#4	-18.87% Mar 20, 2014 - Apr 9, 2014	-5.14% Oct 26, 2018 - Jan 8, 2019
#5	-16.00% Dec 29, 2006 - Jan 10, 2007	-1.79% Jan 25, 2018 - Jun 19, 2018
#6	-16.00% Dec 21, 2006 - Dec 29, 2006	-1.61% Feb 17, 2017 - Aug 21, 2017
#7	-7.58% Mar 26, 2007 - Apr 13, 2007	-0.99% Sep 13, 2018 - Oct 2, 2018
#8	-5.95% Mar 17, 2014 - Mar 20, 2014	-0.69% Jun 19, 2018 - Jul 31, 2018
#9	-5.63% Apr 18, 2007 - Apr 26, 2007	-0.49% Aug 8, 2018 - Sep 13, 2018
#10	N/A	-0.40% Aug 23, 2017 - Oct 20, 2017
#11	N/A	-0.29% Oct 2, 2018 - Oct 8, 2018
#12	N/A	-0.10% Feb 15, 2017 - Feb 17, 2017