ORGO vs PALI

Comparison between Organogenesis Holdings Inc - Class A (ORGO, Company) and Palisade Bio Inc (PALI, Company).

Both ORGO and PALI are from the Healthcare sector.

5-Year PerformanceORGO has outperformed PALI, delivering a return of -30.2% compared to -76.1%

ORGO vs PALI - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	ORGO(COMPANY)	PALI(COMPANY)
Market Cap	$318M	$318M
Max Drawdown	98.74%	100.00%
Sharpe Ratio	-0.64	0.99
5Y Beta	1.94	0.00
Industry	Drug Manufacturers - Specialty & Generic	Biotechnology
P/E Ratio	91.41	-10.99
Forward P/E	12.67	N/A
5Y EPS CAGR	-40.50%	N/A
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	5.37%	-3.90%
P/S Ratio	0.62	11.78
P/B Ratio	1.42	2.61

Market Cap

ORGO

$318M

Winner

PALI

$318M

Max Drawdown

Winner

ORGO

98.74%

PALI

100.00%

Sharpe Ratio

ORGO

-0.64

Winner

PALI

0.99

5Y Beta

ORGO

1.94

Winner

PALI

0.00

Industry

ORGO

Drug Manufacturers - Specialty & Generic

PALI

Biotechnology

P/E Ratio

ORGO

91.41

Winner

PALI

-10.99

Forward P/E

ORGO

12.67

PALI

N/A

5Y EPS CAGR

ORGO

-40.50%

PALI

N/A

Debt to Equity

ORGO

0.00%

PALI

0.00%

Free Cash Flow Yield

Winner

ORGO

5.37%

PALI

-3.90%

P/S Ratio

Winner

ORGO

0.62

PALI

11.78

P/B Ratio

Winner

ORGO

1.42

PALI

2.61

ORGO vs PALI - Historical Returns

Returns include dividend reinvestment.

Period	ORGO	PALI
1 month	+4.55%	-9.42%
3 months	+5.42%	+3.59%
6 months	-34.96%	+20.96%
1 year	-49.60%	+62.90%
5 years(CAGR)	-30.25%	-76.14%
10 years(CAGR)	-13.16%	-69.46%
Max(CAGR)	-13.16%	-50.95%

Winner

ORGO

+4.55%

PALI

-9.42%

Winner

ORGO

+5.42%

PALI

+3.59%

ORGO

-34.96%

Winner

PALI

+20.96%

ORGO

-49.60%

Winner

PALI

+62.90%

5Y(CAGR)

Winner

ORGO

-30.25%

PALI

-76.14%

10Y(CAGR)

Winner

ORGO

-13.16%

PALI

-69.46%

Max(CAGR)

Winner

ORGO

-13.16%

PALI

-50.95%

ORGO vs PALI - Annual Returns (2006 - 2026)

Returns include dividend reinvestment.

Year	ORGO	PALI
2026	-45.42%	-19.20%
2025	+70.96%	+26.34%
2024	-21.57%	-81.00%
2023	+56.70%	-84.55%
2022	-71.89%	-93.11%
2021	+17.86%	-78.96%
2020	+57.53%	-20.00%
2019	-52.61%	-84.99%
2018	+2.42%	-84.58%
2017	+1.74%	-57.46%
2016	N/A	-73.46%
2015	N/A	-63.35%
2014	N/A	-13.92%
2013	N/A	+140.50%
2012	N/A	+9.00%
2011	N/A	-55.53%
2010	N/A	+14.59%
2009	N/A	+7.19%
2008	N/A	-55.00%
2007	N/A	+48.02%
2006	N/A	+50.00%

ORGO vs PALI Drawdown Comparison

The maximum drawdown for ORGO was -98.74%, occurring on Mar 24, 2023. This drawdown has not yet recovered.

The maximum drawdown for PALI was -100.00%, occurring on Sep 10, 2025. This drawdown has not yet recovered.

The current ORGO drawdown is -98.31%. The current PALI drawdown is -100.00%.

Rank	ORGO	PALI
#1	-98.74% Jan 11, 2019 - Mar 24, 2023	-100.00% Apr 9, 2014 - Sep 10, 2025
#2	-6.43% Oct 8, 2018 - Oct 26, 2018	-88.86% Apr 26, 2007 - Mar 17, 2014
#3	-5.97% Oct 24, 2017 - Jan 25, 2018	-24.62% Jan 10, 2007 - Mar 26, 2007
#4	-5.14% Oct 26, 2018 - Jan 8, 2019	-18.87% Mar 20, 2014 - Apr 9, 2014
#5	-1.79% Jan 25, 2018 - Jun 19, 2018	-16.00% Dec 29, 2006 - Jan 10, 2007
#6	-1.61% Feb 17, 2017 - Aug 21, 2017	-16.00% Dec 21, 2006 - Dec 29, 2006
#7	-0.99% Sep 13, 2018 - Oct 2, 2018	-7.58% Mar 26, 2007 - Apr 13, 2007
#8	-0.69% Jun 19, 2018 - Jul 31, 2018	-5.95% Mar 17, 2014 - Mar 20, 2014
#9	-0.49% Aug 8, 2018 - Sep 13, 2018	-5.63% Apr 18, 2007 - Apr 26, 2007
#10	-0.40% Aug 23, 2017 - Oct 20, 2017	N/A
#11	-0.29% Oct 2, 2018 - Oct 8, 2018	N/A
#12	-0.10% Feb 15, 2017 - Feb 17, 2017	N/A