OPTN vs CUE

Comparison between OptiNose Inc (OPTN, Company) and Cue Biopharma Inc (CUE, Company).

5-Year PerformanceOPTN has outperformed CUE, delivering a return of -31.8% compared to -36.3%

OPTN vs CUE - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	OPTN(COMPANY)	CUE(COMPANY)
Market Cap	$112M	$111M
Max Drawdown	98.88%	99.42%
Sharpe Ratio	-0.38	0.84
5Y Beta	N/A	1.65
Industry	N/A	Biotechnology
P/E Ratio	-3.59	-4.68
5Y EPS CAGR	N/A	-30.28%
Debt to Equity	1844.46%	0.00%
Free Cash Flow Yield	-30.58%	-22.10%
P/S Ratio	1.37	4.25
P/B Ratio	-1.83	6.65

Market Cap

Winner

OPTN

$112M

CUE

$111M

Max Drawdown

Winner

OPTN

98.88%

CUE

99.42%

Sharpe Ratio

OPTN

-0.38

Winner

CUE

0.84

5Y Beta

OPTN

N/A

CUE

1.65

Industry

OPTN

N/A

CUE

Biotechnology

P/E Ratio

OPTN

-3.59

Winner

CUE

-4.68

5Y EPS CAGR

OPTN

N/A

CUE

-30.28%

Debt to Equity

OPTN

1844.46%

Winner

CUE

0.00%

Free Cash Flow Yield

OPTN

-30.58%

Winner

CUE

-22.10%

P/S Ratio

Winner

OPTN

1.37

CUE

4.25

P/B Ratio

Winner

OPTN

-1.83

CUE

6.65

OPTN vs CUE - Historical Returns

Returns include dividend reinvestment.

Period	OPTN	CUE
1 month	+4.80%	+23.01%
3 months	+66.38%	+99.03%
6 months	+62.03%	+190.26%
1 year	-44.83%	+23.93%
5 years(CAGR)	-31.84%	-36.27%
10 years(CAGR)	N/A	-24.07%
Max(CAGR)	-35.98%	-24.07%

OPTN

+4.80%

Winner

CUE

+23.01%

OPTN

+66.38%

Winner

CUE

+99.03%

OPTN

+62.03%

Winner

CUE

+190.26%

OPTN

-44.83%

Winner

CUE

+23.93%

5Y(CAGR)

Winner

OPTN

-31.84%

CUE

-36.27%

10Y(CAGR)

OPTN

N/A

CUE

-24.07%

Max(CAGR)

OPTN

-35.98%

Winner

CUE

-24.07%

OPTN vs CUE - Annual Returns (2017 - 2026)

Returns include dividend reinvestment.

Year	OPTN	CUE
2026	N/A	+226.91%
2025	+43.28%	-71.98%
2024	-64.37%	-60.79%
2023	-29.51%	-0.75%
2022	-2.63%	-76.79%
2021	-61.88%	-8.50%
2020	-51.12%	-23.30%
2019	+34.99%	+207.66%
2018	-67.49%	-59.59%
2017	-0.53%	N/A

OPTN vs CUE Drawdown Comparison

The maximum drawdown for OPTN was -98.88%, occurring on Jan 14, 2025. This drawdown has not yet recovered.

The maximum drawdown for CUE was -99.42%, occurring on Apr 6, 2026. This drawdown has not yet recovered.

The current OPTN drawdown is -97.85%. The current CUE drawdown is -96.41%.

Rank	OPTN	CUE
#1	-98.88% Jul 9, 2018 - Jan 14, 2025	-99.42% Jun 2, 2020 - Apr 6, 2026
#2	-26.78% Nov 6, 2017 - Jan 29, 2018	-74.78% Mar 8, 2018 - Dec 26, 2019
#3	-23.58% Jan 29, 2018 - Apr 26, 2018	-55.77% Mar 5, 2020 - Apr 22, 2020
#4	-12.98% May 15, 2018 - Jun 22, 2018	-21.64% Dec 27, 2019 - Feb 10, 2020
#5	-3.11% Oct 16, 2017 - Oct 25, 2017	-15.71% Feb 20, 2020 - Mar 4, 2020
#6	-2.91% Oct 27, 2017 - Nov 6, 2017	-13.52% Jan 25, 2018 - Mar 5, 2018
#7	-2.89% Jun 22, 2018 - Jun 26, 2018	-13.25% Feb 11, 2020 - Feb 19, 2020
#8	-1.69% Jun 28, 2018 - Jul 9, 2018	-12.91% Apr 29, 2020 - May 8, 2020
#9	-1.68% Apr 30, 2018 - May 4, 2018	-11.07% May 21, 2020 - Jun 2, 2020
#10	-0.60% May 4, 2018 - May 8, 2018	-10.51% May 8, 2020 - May 20, 2020
#11	-0.57% Apr 26, 2018 - Apr 30, 2018	-6.95% Jan 16, 2018 - Jan 23, 2018
#12	-0.49% Jun 26, 2018 - Jun 28, 2018	-2.67% Jan 5, 2018 - Jan 11, 2018
#13	-0.41% May 8, 2018 - May 10, 2018	-1.10% Apr 23, 2020 - Apr 27, 2020
#14	N/A	-0.61% Mar 6, 2018 - Mar 8, 2018