OPRX vs NYXH

Comparison between OptimizeRx Corp (OPRX, Company) and Nyxoah SA (NYXH, Company).

Both OPRX and NYXH are from the Healthcare sector.

5-Year PerformanceOPRX has outperformed NYXH, delivering a return of -35.1% compared to -46.3%

OPRX vs NYXH - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	OPRX(COMPANY)	NYXH(COMPANY)
Market Cap	$121M	$122M
Max Drawdown	99.32%	96.46%
Sharpe Ratio	-0.64	-1.60
5Y Beta	1.60	0.85
Industry	Health Information Services	Medical Instruments & Supplies
P/E Ratio	17.67	-1.10
Forward P/E	7.02	N/A
PEG Ratio	1.61	-0.05
5Y EPS CAGR	N/A	24.31%
Debt to Equity	18.01%	100.58%
Free Cash Flow Yield	11.82%	-70.32%
P/S Ratio	1.09	8.72
P/B Ratio	0.94	3.18

Market Cap

OPRX

$121M

Winner

NYXH

$122M

Max Drawdown

OPRX

99.32%

Winner

NYXH

96.46%

Sharpe Ratio

Winner

OPRX

-0.64

NYXH

-1.60

5Y Beta

OPRX

1.60

Winner

NYXH

0.85

Industry

OPRX

Health Information Services

NYXH

Medical Instruments & Supplies

P/E Ratio

OPRX

17.67

Winner

NYXH

-1.10

Forward P/E

OPRX

7.02

NYXH

N/A

PEG Ratio

OPRX

1.61

Winner

NYXH

-0.05

5Y EPS CAGR

OPRX

N/A

NYXH

24.31%

Debt to Equity

Winner

OPRX

18.01%

NYXH

100.58%

Free Cash Flow Yield

Winner

OPRX

11.82%

NYXH

-70.32%

P/S Ratio

Winner

OPRX

1.09

NYXH

8.72

P/B Ratio

Winner

OPRX

0.94

NYXH

3.18

OPRX vs NYXH - Historical Returns

Returns include dividend reinvestment.

Period	OPRX	NYXH
1 month	+36.78%	-6.37%
3 months	-3.12%	-51.96%
6 months	-47.90%	-68.66%
1 year	-54.90%	-81.11%
5 years(CAGR)	-35.09%	-46.33%
10 years(CAGR)	+18.37%	N/A
Max(CAGR)	+15.21%	-41.35%

Winner

OPRX

+36.78%

NYXH

-6.37%

Winner

OPRX

-3.12%

NYXH

-51.96%

Winner

OPRX

-47.90%

NYXH

-68.66%

Winner

OPRX

-54.90%

NYXH

-81.11%

5Y(CAGR)

Winner

OPRX

-35.09%

NYXH

-46.33%

10Y(CAGR)

OPRX

+18.37%

NYXH

N/A

Max(CAGR)

Winner

OPRX

+15.21%

NYXH

-41.35%

OPRX vs NYXH - Annual Returns (2007 - 2026)

Returns include dividend reinvestment.

Year	OPRX	NYXH
2026	-50.00%	-67.33%
2025	+135.32%	-49.12%
2024	-65.38%	+69.31%
2023	-16.41%	-12.29%
2022	-73.30%	-77.32%
2021	+86.18%	-4.17%
2020	+212.54%	N/A
2019	-14.70%	N/A
2018	+612.34%	N/A
2017	+93.83%	N/A
2016	-34.68%	N/A
2015	+9.90%	N/A
2014	-30.06%	N/A
2013	+66.67%	N/A
2012	+19.10%	N/A
2011	-11.00%	N/A
2010	-63.56%	N/A
2009	-54.83%	N/A
2008	+82700.00%	N/A
2007	-98.81%	N/A

OPRX vs NYXH Drawdown Comparison

The maximum drawdown for OPRX was -99.32%, occurring on Nov 29, 2007. Recovery took 196 trading sessions.

The maximum drawdown for NYXH was -96.46%, occurring on Jun 10, 2026. This drawdown has not yet recovered.

The current OPRX drawdown is -93.66%. The current NYXH drawdown is -96.03%.

Rank	OPRX	NYXH
#1	-99.32% Jul 16, 2007 - Apr 28, 2008	-96.46% Aug 6, 2021 - Jun 10, 2026
#2	-96.10% Oct 21, 2021 - Nov 15, 2024	-8.96% Jul 9, 2021 - Aug 6, 2021
#3	-95.40% Feb 13, 2009 - Jun 11, 2018	-3.54% Apr 28, 2021 - Jun 8, 2021
#4	-62.83% Sep 27, 2018 - Aug 24, 2020	-1.67% Jul 7, 2021 - Jul 9, 2021
#5	-32.49% Feb 19, 2021 - Jun 25, 2021	N/A
#6	-29.76% Sep 18, 2008 - Nov 11, 2008	N/A
#7	-19.58% Jun 25, 2021 - Aug 5, 2021	N/A
#8	-14.47% Aug 5, 2021 - Sep 2, 2021	N/A
#9	-13.71% Nov 13, 2020 - Nov 25, 2020	N/A
#10	-12.82% Oct 7, 2020 - Oct 15, 2020	N/A
#11	-10.12% Aug 31, 2020 - Sep 15, 2020	N/A
#12	-9.71% Oct 15, 2020 - Nov 10, 2020	N/A
#13	-8.57% Jun 11, 2018 - Jun 18, 2018	N/A
#14	-8.57% Sep 3, 2021 - Sep 17, 2021	N/A
#15	-7.84% Sep 20, 2018 - Sep 27, 2018	N/A