OPRX vs KLRS

Comparison between OptimizeRx Corp (OPRX, Company) and Kalaris Therapeutics Inc (KLRS, Company).

Both OPRX and KLRS are from the Healthcare sector.

5-Year PerformanceOPRX has outperformed KLRS, delivering a return of -36.4% compared to -61.4%

OPRX vs KLRS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	OPRX(COMPANY)	KLRS(COMPANY)
Market Cap	$95M	$96M
Max Drawdown	99.32%	99.79%
Sharpe Ratio	-1.03	0.81
5Y Beta	1.56	0.86
Industry	Health Information Services	Biotechnology
P/E Ratio	13.89	-1.93
Forward P/E	5.56	N/A
PEG Ratio	1.61	N/A
5Y EPS CAGR	N/A	-39.47%
Debt to Equity	18.01%	0.00%
Free Cash Flow Yield	15.03%	-44.65%
P/S Ratio	0.89	N/A
P/B Ratio	0.74	1.44

Market Cap

OPRX

$95M

Winner

KLRS

$96M

Max Drawdown

Winner

OPRX

99.32%

KLRS

99.79%

Sharpe Ratio

OPRX

-1.03

Winner

KLRS

0.81

5Y Beta

OPRX

1.56

Winner

KLRS

0.86

Industry

OPRX

Health Information Services

KLRS

Biotechnology

P/E Ratio

OPRX

13.89

Winner

KLRS

-1.93

Forward P/E

OPRX

5.56

KLRS

N/A

PEG Ratio

OPRX

1.61

KLRS

N/A

5Y EPS CAGR

OPRX

N/A

KLRS

-39.47%

Debt to Equity

OPRX

18.01%

Winner

KLRS

0.00%

Free Cash Flow Yield

Winner

OPRX

15.03%

KLRS

-44.65%

P/S Ratio

OPRX

0.89

KLRS

N/A

P/B Ratio

Winner

OPRX

0.74

KLRS

1.44

OPRX vs KLRS - Historical Returns

Returns include dividend reinvestment.

Period	OPRX	KLRS
1 month	-17.51%	-9.60%
3 months	-11.80%	-52.78%
6 months	-60.85%	-51.18%
1 year	-65.25%	+56.88%
5 years(CAGR)	-36.40%	-61.41%
10 years(CAGR)	+17.42%	N/A
Max(CAGR)	+14.26%	-56.65%

OPRX

-17.51%

Winner

KLRS

-9.60%

Winner

OPRX

-11.80%

KLRS

-52.78%

OPRX

-60.85%

Winner

KLRS

-51.18%

OPRX

-65.25%

Winner

KLRS

+56.88%

5Y(CAGR)

Winner

OPRX

-36.40%

KLRS

-61.41%

10Y(CAGR)

OPRX

+17.42%

KLRS

N/A

Max(CAGR)

Winner

OPRX

+14.26%

KLRS

-56.65%

OPRX vs KLRS - Annual Returns (2007 - 2026)

Returns include dividend reinvestment.

Year	OPRX	KLRS
2026	-57.89%	-47.83%
2025	+135.32%	-18.45%
2024	-65.38%	-38.98%
2023	-16.41%	-87.00%
2022	-73.30%	-62.06%
2021	+86.18%	-67.36%
2020	+212.54%	+51.40%
2019	-14.70%	N/A
2018	+612.34%	N/A
2017	+93.83%	N/A
2016	-34.68%	N/A
2015	+9.90%	N/A
2014	-30.06%	N/A
2013	+66.67%	N/A
2012	+19.10%	N/A
2011	-11.00%	N/A
2010	-63.56%	N/A
2009	-54.83%	N/A
2008	+82700.00%	N/A
2007	-98.81%	N/A

OPRX vs KLRS Drawdown Comparison

The maximum drawdown for OPRX was -99.32%, occurring on Nov 29, 2007. Recovery took 196 trading sessions.

The maximum drawdown for KLRS was -99.79%, occurring on Aug 14, 2025. This drawdown has not yet recovered.

The current OPRX drawdown is -94.66%. The current KLRS drawdown is -99.60%.

Rank	OPRX	KLRS
#1	-99.32% Jul 16, 2007 - Apr 28, 2008	-99.79% Dec 4, 2020 - Aug 14, 2025
#2	-96.10% Oct 21, 2021 - Nov 15, 2024	-50.70% Aug 11, 2020 - Dec 3, 2020
#3	-95.40% Feb 13, 2009 - Jun 11, 2018	-1.93% Jul 30, 2020 - Aug 3, 2020
#4	-62.83% Sep 27, 2018 - Aug 24, 2020	N/A
#5	-32.49% Feb 19, 2021 - Jun 25, 2021	N/A
#6	-29.76% Sep 18, 2008 - Nov 11, 2008	N/A
#7	-19.58% Jun 25, 2021 - Aug 5, 2021	N/A
#8	-14.47% Aug 5, 2021 - Sep 2, 2021	N/A
#9	-13.71% Nov 13, 2020 - Nov 25, 2020	N/A
#10	-12.82% Oct 7, 2020 - Oct 15, 2020	N/A
#11	-10.12% Aug 31, 2020 - Sep 15, 2020	N/A
#12	-9.71% Oct 15, 2020 - Nov 10, 2020	N/A
#13	-8.57% Jun 11, 2018 - Jun 18, 2018	N/A
#14	-8.57% Sep 3, 2021 - Sep 17, 2021	N/A
#15	-7.84% Sep 20, 2018 - Sep 27, 2018	N/A