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OBIO vs AKBA

Comparison between Orchestra BioMed Holdings Inc (OBIO, Company) and Akebia Therapeutics Inc (AKBA, Company).

Both OBIO and AKBA are from the Healthcare sector.

5-Year PerformanceOBIO has outperformed AKBA, delivering a return of -17.9% compared to -22.6%

OBIO vs AKBA - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap
Winner
OBIO
$236M
AKBA
$234M
Max Drawdown
Winner
OBIO
89.40%
AKBA
99.14%
Sharpe Ratio
Winner
OBIO
0.49
AKBA
-1.34
5Y Beta
OBIO
1.63
Winner
AKBA
1.26
Industry
OBIO
Biotechnology
AKBA
Drug Manufacturers - Specialty & Generic
P/E Ratio
OBIO
-3.61
Winner
AKBA
-11.34
Forward P/E
OBIO
N/A
AKBA
28.74
PEG Ratio
OBIO
N/A
AKBA
0.00
5Y EPS CAGR
OBIO
N/A
AKBA
-35.14%
Debt to Equity
Winner
OBIO
36.41%
AKBA
178.59%
Free Cash Flow Yield
OBIO
-23.37%
Winner
AKBA
25.67%
P/S Ratio
OBIO
7.36
Winner
AKBA
1.06
P/B Ratio
Winner
OBIO
5.84
AKBA
8.95

OBIO vs AKBA - Historical Returns

Returns include dividend reinvestment.

1M
OBIO
-2.76%
Winner
AKBA
+0.99%
3M
Winner
OBIO
-16.05%
AKBA
-31.54%
6M
Winner
OBIO
-10.00%
AKBA
-36.65%
1Y
Winner
OBIO
+15.18%
AKBA
-70.86%
5Y(CAGR)
Winner
OBIO
-17.93%
AKBA
-22.59%
10Y(CAGR)
OBIO
N/A
AKBA
-18.57%
Max(CAGR)
Winner
OBIO
-16.82%
AKBA
-23.41%

OBIO vs AKBA - Annual Returns (2014 - 2026)

Returns include dividend reinvestment.

YearOBIOAKBA
2026-10.21%-34.19%
2025-22.86%-15.26%
2024-54.44%+49.61%
2023-9.06%+99.20%
2022+0.71%-76.45%
2021-22.46%-22.74%
2020+12.37%-55.84%
2019N/A+8.97%
2018N/A-63.06%
2017N/A+41.62%
2016N/A-17.12%
2015N/A+12.35%
2014N/A-56.40%

OBIO vs AKBA Drawdown Comparison

The maximum drawdown for OBIO was -89.40%, occurring on Sep 23, 2025. This drawdown has not yet recovered.

The maximum drawdown for AKBA was -99.14%, occurring on Nov 29, 2022. This drawdown has not yet recovered.

The current OBIO drawdown is -82.55%. The current AKBA drawdown is -96.50%.

RankOBIOAKBA
#1-89.40%
Apr 12, 2023 - Sep 23, 2025
-99.14%
Jun 20, 2014 - Nov 29, 2022
#2-42.60%
Feb 16, 2021 - Mar 6, 2023
-36.84%
Mar 20, 2014 - Apr 21, 2014
#3-33.00%
Mar 6, 2023 - Mar 31, 2023
-21.82%
Apr 21, 2014 - Jun 9, 2014
#4-14.37%
Aug 6, 2020 - Dec 30, 2020
-4.91%
Jun 9, 2014 - Jun 20, 2014
#5-13.31%
Dec 30, 2020 - Feb 8, 2021
N/A
#6-5.52%
Mar 31, 2023 - Apr 5, 2023
N/A
#7-1.63%
Apr 5, 2023 - Apr 11, 2023
N/A
#8-0.53%
Feb 8, 2021 - Feb 10, 2021
N/A

Correlation

Correlation between OBIO and AKBA is 0.02 which considered as a very weak or no correlation - the stocks move independently of each other.

0.02
-101

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