NYXH vs OPRX

Comparison between Nyxoah SA (NYXH, Company) and OptimizeRx Corp (OPRX, Company).

Both NYXH and OPRX are from the Healthcare sector.

5-Year PerformanceOPRX has outperformed NYXH, delivering a return of -35.1% compared to -46.3%

NYXH vs OPRX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	NYXH(COMPANY)	OPRX(COMPANY)
Market Cap	$122M	$121M
Max Drawdown	96.46%	99.32%
Sharpe Ratio	-1.60	-0.64
5Y Beta	0.85	1.60
Industry	Medical Instruments & Supplies	Health Information Services
P/E Ratio	-1.10	17.67
Forward P/E	N/A	7.02
PEG Ratio	-0.05	1.61
5Y EPS CAGR	24.31%	N/A
Debt to Equity	100.58%	18.01%
Free Cash Flow Yield	-70.32%	11.82%
P/S Ratio	8.72	1.09
P/B Ratio	3.18	0.94

Market Cap

Winner

NYXH

$122M

OPRX

$121M

Max Drawdown

Winner

NYXH

96.46%

OPRX

99.32%

Sharpe Ratio

NYXH

-1.60

Winner

OPRX

-0.64

5Y Beta

Winner

NYXH

0.85

OPRX

1.60

Industry

NYXH

Medical Instruments & Supplies

OPRX

Health Information Services

P/E Ratio

Winner

NYXH

-1.10

OPRX

17.67

Forward P/E

NYXH

N/A

OPRX

7.02

PEG Ratio

Winner

NYXH

-0.05

OPRX

1.61

5Y EPS CAGR

NYXH

24.31%

OPRX

N/A

Debt to Equity

NYXH

100.58%

Winner

OPRX

18.01%

Free Cash Flow Yield

NYXH

-70.32%

Winner

OPRX

11.82%

P/S Ratio

NYXH

8.72

Winner

OPRX

1.09

P/B Ratio

NYXH

3.18

Winner

OPRX

0.94

NYXH vs OPRX - Historical Returns

Returns include dividend reinvestment.

Period	NYXH	OPRX
1 month	-6.37%	+36.78%
3 months	-51.96%	-3.12%
6 months	-68.66%	-47.90%
1 year	-81.11%	-54.90%
5 years(CAGR)	-46.33%	-35.09%
10 years(CAGR)	N/A	+18.37%
Max(CAGR)	-41.35%	+15.21%

NYXH

-6.37%

Winner

OPRX

+36.78%

NYXH

-51.96%

Winner

OPRX

-3.12%

NYXH

-68.66%

Winner

OPRX

-47.90%

NYXH

-81.11%

Winner

OPRX

-54.90%

5Y(CAGR)

NYXH

-46.33%

Winner

OPRX

-35.09%

10Y(CAGR)

NYXH

N/A

OPRX

+18.37%

Max(CAGR)

NYXH

-41.35%

Winner

OPRX

+15.21%

NYXH vs OPRX - Annual Returns (2007 - 2026)

Returns include dividend reinvestment.

Year	NYXH	OPRX
2026	-67.33%	-50.00%
2025	-49.12%	+135.32%
2024	+69.31%	-65.38%
2023	-12.29%	-16.41%
2022	-77.32%	-73.30%
2021	-4.17%	+86.18%
2020	N/A	+212.54%
2019	N/A	-14.70%
2018	N/A	+612.34%
2017	N/A	+93.83%
2016	N/A	-34.68%
2015	N/A	+9.90%
2014	N/A	-30.06%
2013	N/A	+66.67%
2012	N/A	+19.10%
2011	N/A	-11.00%
2010	N/A	-63.56%
2009	N/A	-54.83%
2008	N/A	+82700.00%
2007	N/A	-98.81%

NYXH vs OPRX Drawdown Comparison

The maximum drawdown for NYXH was -96.46%, occurring on Jun 10, 2026. This drawdown has not yet recovered.

The maximum drawdown for OPRX was -99.32%, occurring on Nov 29, 2007. Recovery took 196 trading sessions.

The current NYXH drawdown is -96.03%. The current OPRX drawdown is -93.66%.

Rank	NYXH	OPRX
#1	-96.46% Aug 6, 2021 - Jun 10, 2026	-99.32% Jul 16, 2007 - Apr 28, 2008
#2	-8.96% Jul 9, 2021 - Aug 6, 2021	-96.10% Oct 21, 2021 - Nov 15, 2024
#3	-3.54% Apr 28, 2021 - Jun 8, 2021	-95.40% Feb 13, 2009 - Jun 11, 2018
#4	-1.67% Jul 7, 2021 - Jul 9, 2021	-62.83% Sep 27, 2018 - Aug 24, 2020
#5	N/A	-32.49% Feb 19, 2021 - Jun 25, 2021
#6	N/A	-29.76% Sep 18, 2008 - Nov 11, 2008
#7	N/A	-19.58% Jun 25, 2021 - Aug 5, 2021
#8	N/A	-14.47% Aug 5, 2021 - Sep 2, 2021
#9	N/A	-13.71% Nov 13, 2020 - Nov 25, 2020
#10	N/A	-12.82% Oct 7, 2020 - Oct 15, 2020
#11	N/A	-10.12% Aug 31, 2020 - Sep 15, 2020
#12	N/A	-9.71% Oct 15, 2020 - Nov 10, 2020
#13	N/A	-8.57% Jun 11, 2018 - Jun 18, 2018
#14	N/A	-8.57% Sep 3, 2021 - Sep 17, 2021
#15	N/A	-7.84% Sep 20, 2018 - Sep 27, 2018