NXTI vs FMED
Comparison between SIMPLIFY NEXT INTANGIBLE CORE INDEX ETF (NXTI, ETF) and FIDELITY DISRUPTIVE MEDICINE ETF (FMED, ETF).
NXTI vs FMED - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Net Assets
NXTI
$41M
Winner
FMED
$41M
Expense Ratio
Winner
NXTI
0.25%
FMED
0.50%
Max Drawdown
Winner
NXTI
20.46%
FMED
21.84%
Sharpe Ratio
Winner
NXTI
0.73
FMED
0.03
5Y Beta
NXTI
0.95
Winner
FMED
0.79
P/E Ratio
NXTI
26.34
Winner
FMED
-35.26
Forward P/E
Winner
NXTI
20.51
FMED
21.86
5Y EPS CAGR
Winner
NXTI
12.67%
FMED
6.65%
Debt to Equity
NXTI
65.82%
Winner
FMED
14.39%
P/S Ratio
Winner
NXTI
2.62
FMED
4.72
P/B Ratio
NXTI
5.07
Winner
FMED
4.48
NXTI vs FMED - Holdings Comparison
NXTI and FMED have 8 common holdings. Overlap is 1.39%
NXTI's top 25 holdings weight is 57.66%. FMED's top 25 holdings weight is 72.01%.
| Rank | NXTI | FMED |
|---|---|---|
| #1 | CISCO SYSTEMS INC (CSCO) - 6.13% | n/a (n/a) - 12.74% |
| #2 | n/a (PLTR) - 4.29% | n/a (LFST) - 4.42% |
| #3 | WALMART INC (WMT) - 3.88% | UCB SA (n/a) - 4.35% |
| #4 | INTERNATIONAL BUSINESS MACHINES CORP (IBM) - 3.80% | n/a (TXG) - 3.47% |
| #5 | JOHNSON & JOHNSON (JNJ) - 3.39% | DANAHER CORP (DHR) - 3.39% |
| #6 | QUALCOMM INC (QCOM) - 3.24% | LEGEND BIOTECH CORP ADR (LEGN) - 3.15% |
| #7 | n/a (DELL) - 3.23% | INTUITIVE SURGICAL INC (ISRG) - 2.84% |
| #8 | BERKSHIRE HATHAWAY INC CLASS B (BRK-B) - 2.98% | ARGENX SE ADR (ARGX) - 2.75% |
| #9 | PALO ALTO NETWORKS INC (PANW) - 2.84% | COGENT BIOSCIENCES INC (COGT) - 2.75% |
| #10 | SEAGATE TECHNOLOGY HOLDINGS PLC (STX) - 2.20% | ALNYLAM PHARMACEUTICALS INC (ALNY) - 2.72% |
| #11 | WESTERN DIGITAL CORP (WDC) - 2.08% | THERMO FISHER SCIENTIFIC INC (TMO) - 2.42% |
| #12 | MERCK & CO INC (MRK) - 1.82% | UNITEDHEALTH GROUP INC (UNH) - 2.30% |
| #13 | MASTERCARD INC CLASS A (MA) - 1.76% | BIO-TECHNE CORP (TECH) - 2.22% |
| #14 | EXXON MOBIL CORP (XOM) - 1.76% | EDWARDS LIFESCIENCES CORP (EW) - 2.20% |
| #15 | SERVICENOW INC (NOW) - 1.67% | ASCENDIS PHARMA AS (ASND) - 2.10% |
| #16 | ADOBE INC (ADBE) - 1.43% | MODERNA INC (MRNA) - 2.09% |
| #17 | CADENCE DESIGN SYSTEMS INC (CDNS) - 1.39% | CARIS LIFE SCIENCES INC (CAI) - 1.91% |
| #18 | FORTINET INC (FTNT) - 1.32% | XENON PHARMACEUTICALS INC (XENE) - 1.88% |
| #19 | SPOTIFY TECHNOLOGY SA (SPOT) - 1.30% | SARTORIUS STEDIM BIOTECH SA (n/a) - 1.87% |
| #20 | GE AEROSPACE (GE) - 1.28% | HEARTFLOW INC (HTFL) - 1.85% |
| #21 | CATERPILLAR INC (CAT) - 1.26% | KYMERA THERAPEUTICS INC ORDINARY SHARES (KYMR) - 1.79% |
| #22 | LAM RESEARCH CORP (LRCX) - 1.23% | INSMED INC (INSM) - 1.79% |
| #23 | APPLIED MATERIALS INC (AMAT) - 1.15% | REVOLUTION MEDICINES INC ORDINARY SHARES (RVMD) - 1.71% |
| #24 | COMCAST CORP CLASS A (CMCSA) - 1.12% | VAXCYTE INC ORDINARY SHARES (PCVX) - 1.67% |
| #25 | DATADOG INC CLASS A (DDOG) - 1.11% | VERACYTE INC (VCYT) - 1.63% |
| Total Holdings | 201 | 73 |
NXTI vs FMED - Historical Returns
Returns include dividend reinvestment.
1M
Winner
NXTI
+5.97%
FMED
-1.41%
3M
Winner
NXTI
+11.00%
FMED
-4.47%
6M
Winner
NXTI
+4.33%
FMED
-13.97%
1Y
Winner
NXTI
+13.46%
FMED
+1.52%
Max(CAGR)
Winner
NXTI
+18.16%
FMED
-1.05%
NXTI vs FMED - Annual Returns (2023 - 2026)
Returns include dividend reinvestment.
| Year | NXTI | FMED |
|---|---|---|
| 2026 | +6.08% | -9.31% |
| 2025 | +16.74% | +9.24% |
| 2024 | +16.21% | +2.42% |
| 2023 | N/A | -4.20% |
NXTI vs FMED Drawdown Comparison
The maximum drawdown for NXTI was -19.65%, occurring on Apr 8, 2025. Recovery took 91 trading sessions.
The maximum drawdown for FMED was -21.84%, occurring on Oct 30, 2023. Recovery took 151 trading sessions.
The current NXTI drawdown is -3.36%. The current FMED drawdown is -15.43%.
| Rank | NXTI | FMED |
|---|---|---|
| #1 | -19.65% Feb 18, 2025 - Jun 30, 2025 | -21.84% Jul 21, 2023 - Feb 27, 2024 |
| #2 | -12.99% Dec 11, 2025 - May 22, 2026 | -19.46% Jan 30, 2025 - Oct 27, 2025 |
| #3 | -7.25% Oct 27, 2025 - Dec 10, 2025 | -18.33% Nov 28, 2025 - Mar 30, 2026 |
| #4 | -6.70% Dec 4, 2024 - Feb 4, 2025 | -8.49% Feb 27, 2024 - Aug 21, 2024 |
| #5 | -6.41% Jul 16, 2024 - Aug 15, 2024 | -7.13% Sep 19, 2024 - Dec 4, 2024 |
| #6 | -3.72% Sep 29, 2025 - Oct 27, 2025 | -6.80% Dec 4, 2024 - Jan 30, 2025 |
| #7 | -3.53% Jun 1, 2026 - Jun 5, 2026 | -4.70% Oct 27, 2025 - Nov 11, 2025 |
| #8 | -3.24% Oct 14, 2024 - Nov 6, 2024 | -4.36% Jun 13, 2023 - Jul 21, 2023 |
| #9 | -3.20% Aug 30, 2024 - Sep 13, 2024 | -1.91% Aug 29, 2024 - Sep 12, 2024 |
| #10 | -3.01% May 21, 2024 - Jun 18, 2024 | -1.33% Nov 12, 2025 - Nov 19, 2025 |
| #11 | -2.50% Jul 28, 2025 - Aug 12, 2025 | -0.82% Sep 16, 2024 - Sep 19, 2024 |
| #12 | -2.28% Nov 13, 2024 - Nov 22, 2024 | -0.51% Nov 19, 2025 - Nov 21, 2025 |
| #13 | -2.12% Jul 3, 2025 - Jul 25, 2025 | -0.40% Aug 23, 2024 - Aug 27, 2024 |
| #14 | -2.07% Apr 23, 2024 - May 6, 2024 | -0.16% Aug 27, 2024 - Aug 29, 2024 |
| #15 | -1.47% Aug 13, 2025 - Aug 28, 2025 | -0.12% Aug 21, 2024 - Aug 23, 2024 |
Correlation
Correlation between NXTI and FMED is 0.39 which considered as a weak positive correlation - the stocks show a slight tendency to move together.
0.39
-101
Dividend Comparison (2024 - 2026)
NXTI vs FMED dividend yield comparison.
| Year | NXTI | FMED |
|---|---|---|
| 2026 | 0.15% | 0.00% |
| 2025 | 0.62% | 0.00% |
| 2024 | 3.70% | 0.46% |
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