NKTR vs ZYME

Comparison between Nektar Therapeutics (NKTR, Company) and Zymeworks BC Inc (ZYME, Company).

Both NKTR and ZYME are from the Healthcare sector.

5-Year PerformanceZYME has outperformed NKTR, delivering a return of -8.2% compared to -22.5%

NKTR vs ZYME - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	NKTR(COMPANY)	ZYME(COMPANY)
Market Cap	$1.71B	$1.71B
Max Drawdown	99.61%	91.81%
Sharpe Ratio	1.52	1.08
5Y Beta	1.81	0.84
Industry	Biotechnology	Biotechnology
P/E Ratio	-7.65	-16.85
Forward P/E	34.01	24.04
PEG Ratio	0.31	0.00
5Y EPS CAGR	-24.01%	N/A
Debt to Equity	24.89%	0.00%
Free Cash Flow Yield	-11.89%	-4.51%
P/S Ratio	42.10	21.15
P/B Ratio	4.03	10.82

Market Cap

Winner

NKTR

$1.71B

ZYME

$1.71B

Max Drawdown

NKTR

99.61%

Winner

ZYME

91.81%

Sharpe Ratio

Winner

NKTR

1.52

ZYME

1.08

5Y Beta

NKTR

1.81

Winner

ZYME

0.84

Industry

NKTR

Biotechnology

ZYME

Biotechnology

P/E Ratio

NKTR

-7.65

Winner

ZYME

-16.85

Forward P/E

NKTR

34.01

Winner

ZYME

24.04

PEG Ratio

NKTR

0.31

Winner

ZYME

0.00

5Y EPS CAGR

NKTR

-24.01%

ZYME

N/A

Debt to Equity

NKTR

24.89%

Winner

ZYME

0.00%

Free Cash Flow Yield

NKTR

-11.89%

Winner

ZYME

-4.51%

P/S Ratio

NKTR

42.10

Winner

ZYME

21.15

P/B Ratio

Winner

NKTR

4.03

ZYME

10.82

NKTR vs ZYME - Historical Returns

Returns include dividend reinvestment.

Period	NKTR	ZYME
1 month	+4.00%	-3.18%
3 months	-24.00%	-15.71%
6 months	+86.90%	-0.52%
1 year	+177.44%	+61.79%
5 years(CAGR)	-22.48%	-8.19%
10 years(CAGR)	-11.22%	+6.43%
Max(CAGR)	-3.91%	+6.43%

Winner

NKTR

+4.00%

ZYME

-3.18%

NKTR

-24.00%

Winner

ZYME

-15.71%

Winner

NKTR

+86.90%

ZYME

-0.52%

Winner

NKTR

+177.44%

ZYME

+61.79%

5Y(CAGR)

NKTR

-22.48%

Winner

ZYME

-8.19%

10Y(CAGR)

NKTR

-11.22%

Winner

ZYME

+6.43%

Max(CAGR)

NKTR

-3.91%

Winner

ZYME

+6.43%

NKTR vs ZYME - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	NKTR	ZYME
2026	+59.74%	-13.15%
2025	+193.31%	+78.15%
2024	+56.36%	+41.04%
2023	-74.20%	+37.80%
2022	-83.46%	-53.71%
2021	-23.50%	-66.53%
2020	-18.89%	-0.69%
2019	-36.91%	+209.46%
2018	-42.98%	+85.05%
2017	+370.61%	-41.59%
2016	-24.26%	N/A
2015	+11.11%	N/A
2014	+30.58%	N/A
2013	+50.53%	N/A
2012	+28.65%	N/A
2011	-55.35%	N/A
2010	+32.75%	N/A
2009	+60.97%	N/A
2008	-15.76%	N/A
2007	-55.97%	N/A
2006	-7.48%	N/A
2005	-16.70%	N/A
2004	+41.54%	N/A
2003	+59.00%	N/A
2002	-55.65%	N/A
2001	-58.31%	N/A
2000	+142.26%	N/A
1999	+58.33%	N/A

NKTR vs ZYME Drawdown Comparison

The maximum drawdown for NKTR was -99.61%, occurring on Nov 28, 2023. This drawdown has not yet recovered.

The maximum drawdown for ZYME was -91.81%, occurring on Sep 7, 2022. This drawdown has not yet recovered.

The current NKTR drawdown is -95.74%. The current ZYME drawdown is -59.30%.

Rank	NKTR	ZYME
#1	-99.61% Mar 8, 2018 - Nov 28, 2023	-91.81% Jan 8, 2021 - Sep 7, 2022
#2	-95.53% Mar 7, 2000 - Jan 9, 2018	-51.24% Jan 22, 2020 - Nov 27, 2020
#3	-22.54% Jan 24, 2000 - Feb 8, 2000	-51.20% May 3, 2017 - Feb 1, 2018
#4	-15.89% Feb 1, 2018 - Feb 23, 2018	-49.91% Jun 1, 2018 - Jun 24, 2019
#5	-10.44% Nov 15, 1999 - Dec 15, 1999	-28.19% Feb 1, 2018 - Apr 26, 2018
#6	-9.53% Feb 17, 2000 - Mar 2, 2000	-14.72% Sep 6, 2019 - Oct 17, 2019
#7	-6.64% Feb 26, 2018 - Mar 2, 2018	-14.38% Dec 4, 2020 - Jan 8, 2021
#8	-5.12% Nov 8, 1999 - Nov 15, 1999	-10.39% Apr 27, 2018 - May 15, 2018
#9	-4.78% Dec 16, 1999 - Dec 20, 1999	-10.05% Dec 4, 2019 - Dec 18, 2019
#10	-4.65% Mar 2, 2018 - Mar 8, 2018	-8.78% Jan 2, 2020 - Jan 17, 2020
#11	-4.58% Dec 27, 1999 - Jan 4, 2000	-8.26% Nov 5, 2019 - Nov 18, 2019
#12	-4.55% Feb 9, 2000 - Feb 16, 2000	-7.96% Jul 9, 2019 - Aug 15, 2019
#13	-3.61% Jan 12, 2018 - Jan 22, 2018	-6.40% Aug 16, 2019 - Aug 28, 2019
#14	-1.62% Jan 23, 2018 - Jan 25, 2018	-4.63% May 30, 2018 - Jun 1, 2018
#15	-1.30% Dec 21, 1999 - Dec 23, 1999	-3.62% Nov 29, 2019 - Dec 4, 2019