MRSN vs CRDL

Comparison between Mersana Therapeutics Inc (MRSN, Company) and Cardiol Therapeutics Inc - Class A (CRDL, Company).

Both MRSN and CRDL are from the Healthcare sector.

5-Year PerformanceCRDL has outperformed MRSN, delivering a return of -9.0% compared to -42.3%

MRSN vs CRDL - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	MRSN(COMPANY)	CRDL(COMPANY)
Market Cap	$145M	$146M
Max Drawdown	99.13%	92.71%
Sharpe Ratio	0.58	0.28
5Y Beta	N/A	1.27
Industry	Biotechnology	Drug Manufacturers - Specialty & Generic
P/E Ratio	-2.04	-4.74
5Y EPS CAGR	-15.54%	-10.43%
Debt to Equity	0.00%	0.48%
Free Cash Flow Yield	-51.16%	-12.04%
P/S Ratio	N/A	1014.87
P/B Ratio	N/A	8.49

Market Cap

MRSN

$145M

Winner

CRDL

$146M

Max Drawdown

MRSN

99.13%

Winner

CRDL

92.71%

Sharpe Ratio

Winner

MRSN

0.58

CRDL

0.28

5Y Beta

MRSN

N/A

CRDL

1.27

Industry

MRSN

Biotechnology

CRDL

Drug Manufacturers - Specialty & Generic

P/E Ratio

MRSN

-2.04

Winner

CRDL

-4.74

5Y EPS CAGR

MRSN

-15.54%

Winner

CRDL

-10.43%

Debt to Equity

Winner

MRSN

0.00%

CRDL

0.48%

Free Cash Flow Yield

MRSN

-51.16%

Winner

CRDL

-12.04%

P/S Ratio

MRSN

N/A

CRDL

1014.87

P/B Ratio

MRSN

N/A

CRDL

8.49

MRSN vs CRDL - Historical Returns

Returns include dividend reinvestment.

Period	MRSN	CRDL
1 month	+4.70%	+27.10%
3 months	+254.63%	+3.03%
6 months	+282.25%	+36.71%
1 year	-14.47%	+27.10%
5 years(CAGR)	-42.31%	-9.01%
10 years(CAGR)	-25.31%	N/A
Max(CAGR)	-25.31%	-12.53%

MRSN

+4.70%

Winner

CRDL

+27.10%

Winner

MRSN

+254.63%

CRDL

+3.03%

Winner

MRSN

+282.25%

CRDL

+36.71%

MRSN

-14.47%

Winner

CRDL

+27.10%

5Y(CAGR)

MRSN

-42.31%

Winner

CRDL

-9.01%

10Y(CAGR)

MRSN

-25.31%

CRDL

N/A

Max(CAGR)

MRSN

-25.31%

Winner

CRDL

-12.53%

MRSN vs CRDL - Annual Returns (2017 - 2026)

Returns include dividend reinvestment.

Year	MRSN	CRDL
2026	+0.14%	+36.79%
2025	-17.34%	-30.38%
2024	-37.00%	+45.45%
2023	-59.51%	+56.12%
2022	-9.01%	-72.58%
2021	-76.55%	-13.65%
2020	+396.46%	-39.59%
2019	+32.95%	-5.49%
2018	-76.54%	N/A
2017	+17.36%	N/A

MRSN vs CRDL Drawdown Comparison

The maximum drawdown for MRSN was -99.13%, occurring on Aug 11, 2025. This drawdown has not yet recovered.

The maximum drawdown for CRDL was -92.71%, occurring on Apr 5, 2023. This drawdown has not yet recovered.

The current MRSN drawdown is -95.78%. The current CRDL drawdown is -78.03%.

Rank	MRSN	CRDL
#1	-99.13% Dec 23, 2020 - Aug 11, 2025	-92.71% Feb 22, 2019 - Apr 5, 2023
#2	-93.61% May 25, 2018 - Jun 25, 2020	-9.26% Feb 4, 2019 - Feb 19, 2019
#3	-34.46% Sep 16, 2020 - Dec 1, 2020	-1.86% Jan 18, 2019 - Jan 29, 2019
#4	-31.86% Oct 3, 2017 - May 22, 2018	-0.20% Jan 16, 2019 - Jan 18, 2019
#5	-30.77% Jun 30, 2020 - Sep 14, 2020	N/A
#6	-14.30% Sep 11, 2017 - Sep 22, 2017	N/A
#7	-11.24% Dec 1, 2020 - Dec 21, 2020	N/A
#8	-5.21% Jun 28, 2017 - Jul 12, 2017	N/A
#9	-5.21% Sep 14, 2020 - Sep 16, 2020	N/A
#10	-4.29% Aug 21, 2017 - Aug 29, 2017	N/A
#11	-4.26% Sep 22, 2017 - Oct 2, 2017	N/A
#12	-3.25% Jul 27, 2017 - Aug 8, 2017	N/A
#13	-2.71% Jun 25, 2020 - Jun 30, 2020	N/A
#14	-2.48% Aug 14, 2017 - Aug 18, 2017	N/A
#15	-2.13% Aug 30, 2017 - Sep 11, 2017	N/A