MREO vs ACST

Comparison between Mereo Biopharma Group Plc (MREO, Company) and Acasti Pharma Inc - Class A (ACST, Company).

5-Year PerformanceMREO has outperformed ACST, delivering a return of -38.6% compared to -49.4%

MREO vs ACST - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	MREO(COMPANY)	ACST(COMPANY)
Market Cap	$53M	$53M
Max Drawdown	96.35%	99.91%
Sharpe Ratio	-0.29	0.52
5Y Beta	1.26	N/A
Industry	Biotechnology	N/A
P/E Ratio	-1.27	-8.78
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-51.14%	-19.23%
P/S Ratio	109.82	477.54
P/B Ratio	1.60	0.64

Market Cap

Winner

MREO

$53M

ACST

$53M

Max Drawdown

Winner

MREO

96.35%

ACST

99.91%

Sharpe Ratio

MREO

-0.29

Winner

ACST

0.52

5Y Beta

MREO

1.26

ACST

N/A

Industry

MREO

Biotechnology

ACST

N/A

P/E Ratio

MREO

-1.27

Winner

ACST

-8.78

Debt to Equity

MREO

0.00%

ACST

0.00%

Free Cash Flow Yield

MREO

-51.14%

Winner

ACST

-19.23%

P/S Ratio

Winner

MREO

109.82

ACST

477.54

P/B Ratio

MREO

1.60

Winner

ACST

0.64

MREO vs ACST - Historical Returns

Returns include dividend reinvestment.

Period	MREO	ACST
1 month	+12.38%	+29.05%
3 months	-19.90%	+9.12%
6 months	-84.80%	-8.53%
1 year	-87.27%	+17.36%
5 years(CAGR)	-38.63%	-49.37%
10 years(CAGR)	N/A	-37.15%
Max(CAGR)	-34.70%	-31.77%

MREO

+12.38%

Winner

ACST

+29.05%

MREO

-19.90%

Winner

ACST

+9.12%

MREO

-84.80%

Winner

ACST

-8.53%

MREO

-87.27%

Winner

ACST

+17.36%

5Y(CAGR)

Winner

MREO

-38.63%

ACST

-49.37%

10Y(CAGR)

MREO

N/A

ACST

-37.15%

Max(CAGR)

MREO

-34.70%

Winner

ACST

-31.77%

MREO vs ACST - Annual Returns (2011 - 2026)

Returns include dividend reinvestment.

Year	MREO	ACST
2026	-38.64%	N/A
2025	-87.82%	N/A
2024	+52.17%	+12.68%
2023	+212.16%	-4.18%
2022	-55.88%	-63.70%
2021	-54.80%	-60.13%
2020	+11.53%	-86.34%
2019	-49.54%	+172.22%
2018	N/A	-16.81%
2017	N/A	-26.89%
2016	N/A	-49.60%
2015	N/A	-49.58%
2014	N/A	-60.00%
2013	N/A	-41.86%
2012	N/A	+62.14%
2011	N/A	+20.83%

MREO vs ACST Drawdown Comparison

The maximum drawdown for MREO was -96.35%, occurring on May 6, 2026. This drawdown has not yet recovered.

The maximum drawdown for ACST was -99.91%, occurring on Sep 22, 2023. This drawdown has not yet recovered.

The current MREO drawdown is -95.18%. The current ACST drawdown is -99.84%.

Rank	MREO	ACST
#1	-96.35% Apr 24, 2019 - May 6, 2026	-99.91% Aug 5, 2013 - Sep 22, 2023
#2	N/A	-26.08% Jun 7, 2011 - Feb 14, 2012
#3	N/A	-22.89% Dec 6, 2012 - Jun 11, 2013
#4	N/A	-18.33% May 2, 2012 - Nov 30, 2012
#5	N/A	-4.47% Jul 30, 2013 - Aug 5, 2013
#6	N/A	-3.67% Mar 19, 2012 - Apr 26, 2012
#7	N/A	-3.64% Jun 11, 2013 - Jun 20, 2013
#8	N/A	-3.34% Jul 1, 2013 - Jul 8, 2013
#9	N/A	-2.68% May 17, 2011 - May 25, 2011
#10	N/A	-1.92% Jul 11, 2013 - Jul 15, 2013
#11	N/A	-1.45% Jun 20, 2013 - Jun 28, 2013
#12	N/A	-1.30% May 26, 2011 - Jun 3, 2011
#13	N/A	-0.31% Jul 24, 2013 - Jul 29, 2013
#14	N/A	-0.15% Nov 30, 2012 - Dec 4, 2012
#15	N/A	-0.13% Apr 27, 2012 - May 2, 2012