MLTX vs TWO

Comparison between MoonLake Immunotherapeutics - Class A (MLTX, Company) and Two Harbors Investment Corp (TWO, Company).

MLTX is from the Healthcare sector, while TWO is from the Real Estate sector.

5-Year PerformanceMLTX has outperformed TWO, delivering a return of +12.2% compared to -3.6%

MLTX vs TWO - Performance Comparison

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Key Characteristics

Financial metrics and valuation ratios

Metric	MLTX(COMPANY)	TWO(COMPANY)
Market Cap	$1.31B	$1.31B
Max Drawdown	90.22%	92.02%
Sharpe Ratio	0.48	0.82
5Y Beta	0.95	0.62
Industry	Biotechnology	Reit - Mortgage
P/E Ratio	-5.14	-3.79
Forward P/E	N/A	10.94
PEG Ratio	-0.03	2.76
Dividend Yield	N/A	11.40%
5Y Dividends CAGR	N/A	-7.04%
Debt to Equity	38.98%	478.53%
Free Cash Flow Yield	-17.08%	2.56%
P/S Ratio	N/A	2.67
P/B Ratio	5.56	1.17

Market Cap

Winner

MLTX

$1.31B

TWO

$1.31B

Max Drawdown

Winner

MLTX

90.22%

TWO

92.02%

Sharpe Ratio

MLTX

0.48

Winner

TWO

0.82

5Y Beta

MLTX

0.95

Winner

TWO

0.62

Industry

MLTX

Biotechnology

TWO

Reit - Mortgage

P/E Ratio

Winner

MLTX

-5.14

TWO

-3.79

Forward P/E

MLTX

N/A

TWO

10.94

PEG Ratio

Winner

MLTX

-0.03

TWO

2.76

Dividend Yield

MLTX

N/A

TWO

11.40%

5Y Dividends CAGR

MLTX

N/A

TWO

-7.04%

Debt to Equity

Winner

MLTX

38.98%

TWO

478.53%

Free Cash Flow Yield

MLTX

-17.08%

Winner

TWO

2.56%

P/S Ratio

MLTX

N/A

TWO

2.67

P/B Ratio

MLTX

5.56

Winner

TWO

1.17

MLTX vs TWO - Historical Returns

Returns include dividend reinvestment.

Period	MLTX	TWO
1 month	+5.23%	+0.65%
3 months	-0.67%	+32.47%
6 months	+20.13%	+28.51%
1 year	-63.34%	+32.43%
5 years(CAGR)	+12.23%	-3.62%
10 years(CAGR)	N/A	-3.60%
Max(CAGR)	+9.97%	+2.40%

Winner

MLTX

+5.23%

TWO

+0.65%

MLTX

-0.67%

Winner

TWO

+32.47%

MLTX

+20.13%

Winner

TWO

+28.51%

MLTX

-63.34%

Winner

TWO

+32.43%

5Y(CAGR)

Winner

MLTX

+12.23%

TWO

-3.62%

10Y(CAGR)

MLTX

N/A

TWO

-3.60%

Max(CAGR)

Winner

MLTX

+9.97%

TWO

+2.40%

MLTX vs TWO - Annual Returns (2009 - 2026)

Returns include dividend reinvestment.

Year	MLTX	TWO
2026	+49.79%	+24.13%
2025	-75.40%	+1.39%
2024	-9.07%	-2.38%
2023	+447.76%	-0.24%
2022	+5.85%	-25.38%
2021	-8.76%	+3.15%
2020	+8.39%	-52.49%
2019	N/A	+27.18%
2018	N/A	-9.54%
2017	N/A	+13.91%
2016	N/A	+18.53%
2015	N/A	-11.36%
2014	N/A	+17.20%
2013	N/A	-10.10%
2012	N/A	+39.18%
2011	N/A	+15.17%
2010	N/A	+17.22%
2009	N/A	+3.87%

MLTX vs TWO Drawdown Comparison

The maximum drawdown for MLTX was -90.22%, occurring on Sep 29, 2025. This drawdown has not yet recovered.

The maximum drawdown for TWO was -84.71%, occurring on Apr 3, 2020. This drawdown has not yet recovered.

The current MLTX drawdown is -71.97%. The current TWO drawdown is -56.53%.

Rank	MLTX	TWO
#1	-90.22% Feb 12, 2024 - Sep 29, 2025	-84.71% Feb 20, 2020 - Apr 3, 2020
#2	-64.60% Apr 5, 2022 - Feb 7, 2023	-31.39% Mar 26, 2013 - Feb 16, 2017
#3	-41.80% Oct 5, 2023 - Dec 27, 2023	-21.96% Oct 5, 2017 - Nov 8, 2019
#4	-25.65% Feb 18, 2021 - Apr 5, 2022	-20.98% Jul 6, 2011 - Feb 17, 2012
#5	-19.79% Mar 8, 2023 - Apr 24, 2023	-16.18% Oct 8, 2012 - Jan 2, 2013
#6	-18.38% Jul 28, 2023 - Oct 5, 2023	-13.53% Jan 4, 2010 - Sep 13, 2010
#7	-15.06% Dec 27, 2023 - Feb 9, 2024	-9.39% Oct 30, 2009 - Dec 8, 2009
#8	-14.12% Apr 24, 2023 - May 4, 2023	-7.76% Mar 9, 2011 - May 19, 2011
#9	-12.27% Jun 9, 2023 - Jun 26, 2023	-5.83% Jun 19, 2017 - Aug 31, 2017
#10	-7.95% Jul 19, 2023 - Jul 26, 2023	-4.86% Apr 27, 2012 - Jun 13, 2012
#11	-7.48% Jul 5, 2023 - Jul 14, 2023	-4.55% Apr 27, 2017 - Jun 1, 2017
#12	-5.83% Oct 22, 2020 - Dec 1, 2020	-4.05% May 19, 2011 - Jun 22, 2011
#13	-5.45% May 10, 2023 - May 25, 2023	-4.04% Dec 8, 2009 - Dec 30, 2009
#14	-5.45% Dec 31, 2020 - Jan 8, 2021	-3.91% Feb 19, 2013 - Feb 28, 2013
#15	-4.78% Jan 8, 2021 - Feb 11, 2021	-3.66% Dec 13, 2010 - Dec 30, 2010

Correlation

Correlation between MLTX and TWO is -0.53 which considered as a moderate negative correlation - the stocks show some tendency to move in opposite directions.

-0.53

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