MKTX vs TNGX

Comparison between MarketAxess Holdings Inc (MKTX, Company) and Tango Therapeutics Inc (TNGX, Company).

MKTX is from the Financial Services sector, while TNGX is from the Healthcare sector.

5-Year PerformanceTNGX has outperformed MKTX, delivering a return of +23.0% compared to -21.8%

MKTX vs TNGX - Performance Comparison

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Key Characteristics

Financial metrics and valuation ratios

Metric	MKTX(COMPANY)	TNGX(COMPANY)
Market Cap	$4.13B	$4.13B
Max Drawdown	80.60%	93.64%
Sharpe Ratio	-2.38	2.32
5Y Beta	-0.14	1.39
Industry	Capital Markets	Biotechnology
P/E Ratio	13.65	-35.46
Forward P/E	14.33	N/A
PEG Ratio	0.28	N/A
Dividend Yield	2.63%	N/A
5Y Dividends CAGR	8.79%	N/A
5Y EPS CAGR	1.15%	N/A
Debt to Equity	19.17%	0.00%
Free Cash Flow Yield	6.56%	-3.45%
P/S Ratio	4.75	73.25
P/B Ratio	3.48	10.60

Market Cap

MKTX

$4.13B

Winner

TNGX

$4.13B

Max Drawdown

Winner

MKTX

80.60%

TNGX

93.64%

Sharpe Ratio

MKTX

-2.38

Winner

TNGX

2.32

5Y Beta

Winner

MKTX

-0.14

TNGX

1.39

Industry

MKTX

Capital Markets

TNGX

Biotechnology

P/E Ratio

MKTX

13.65

Winner

TNGX

-35.46

Forward P/E

MKTX

14.33

TNGX

N/A

PEG Ratio

MKTX

0.28

TNGX

N/A

Dividend Yield

MKTX

2.63%

TNGX

N/A

5Y Dividends CAGR

MKTX

8.79%

TNGX

N/A

5Y EPS CAGR

MKTX

1.15%

TNGX

N/A

Debt to Equity

MKTX

19.17%

Winner

TNGX

0.00%

Free Cash Flow Yield

Winner

MKTX

6.56%

TNGX

-3.45%

P/S Ratio

Winner

MKTX

4.75

TNGX

73.25

P/B Ratio

Winner

MKTX

3.48

TNGX

10.60

MKTX vs TNGX - Historical Returns

Returns include dividend reinvestment.

Period	MKTX	TNGX
1 month	-14.00%	+31.66%
3 months	-33.01%	+80.41%
6 months	-31.78%	+230.91%
1 year	-45.72%	+512.67%
5 years(CAGR)	-21.78%	+22.98%
10 years(CAGR)	-0.62%	N/A
Max(CAGR)	+10.51%	+21.14%

MKTX

-14.00%

Winner

TNGX

+31.66%

MKTX

-33.01%

Winner

TNGX

+80.41%

MKTX

-31.78%

Winner

TNGX

+230.91%

MKTX

-45.72%

Winner

TNGX

+512.67%

5Y(CAGR)

MKTX

-21.78%

Winner

TNGX

+22.98%

10Y(CAGR)

MKTX

-0.62%

TNGX

N/A

Max(CAGR)

MKTX

+10.51%

Winner

TNGX

+21.14%

MKTX vs TNGX - Annual Returns (2004 - 2026)

Returns include dividend reinvestment.

Year	MKTX	TNGX
2026	-31.61%	+246.47%
2025	-18.26%	+183.07%
2024	-19.83%	-69.04%
2023	+3.88%	+35.43%
2022	-29.01%	-33.73%
2021	-26.51%	-3.78%
2020	+50.84%	+11.83%
2019	+82.49%	N/A
2018	+4.66%	N/A
2017	+35.29%	N/A
2016	+35.49%	N/A
2015	+60.05%	N/A
2014	+10.85%	N/A
2013	+86.74%	N/A
2012	+27.24%	N/A
2011	+49.22%	N/A
2010	+49.24%	N/A
2009	+61.04%	N/A
2008	-33.55%	N/A
2007	-4.82%	N/A
2006	+20.94%	N/A
2005	-28.34%	N/A
2004	-2.74%	N/A

MKTX vs TNGX Drawdown Comparison

The maximum drawdown for MKTX was -80.60%, occurring on Oct 17, 2008. Recovery took 1549 trading sessions.

The maximum drawdown for TNGX was -93.64%, occurring on May 8, 2025. Recovery took 1126 trading sessions.

The current MKTX drawdown is -78.08%. The current TNGX drawdown is -1.96%.

Rank	MKTX	TNGX
#1	-80.60% Nov 22, 2004 - Jan 18, 2011	-93.64% Sep 17, 2021 - Mar 16, 2026
#2	-78.95% Dec 22, 2020 - Jun 10, 2026	-29.24% Apr 21, 2026 - Jun 8, 2026
#3	-32.71% Sep 6, 2019 - Apr 16, 2020	-26.94% Feb 22, 2021 - Sep 7, 2021
#4	-32.34% Nov 21, 2013 - Dec 17, 2014	-13.43% Jan 7, 2021 - Feb 22, 2021
#5	-30.38% Mar 28, 2012 - Jan 2, 2013	-9.13% Jun 9, 2026 - Jun 10, 2026
#6	-22.24% Mar 16, 2018 - Dec 7, 2018	-8.46% Apr 2, 2026 - Apr 14, 2026
#7	-20.10% Aug 29, 2011 - Nov 3, 2011	-8.00% Mar 25, 2026 - Mar 31, 2026
#8	-19.95% Jul 9, 2020 - Oct 20, 2020	-6.07% Sep 23, 2020 - Nov 23, 2020
#9	-16.64% Jun 19, 2017 - Jan 5, 2018	-4.65% Dec 1, 2020 - Dec 31, 2020
#10	-16.39% Apr 7, 2011 - Jul 1, 2011	-2.37% Mar 20, 2026 - Mar 24, 2026
#11	-15.90% Sep 15, 2016 - Jan 25, 2017	-1.40% Dec 31, 2020 - Jan 6, 2021
#12	-15.73% Jul 10, 2015 - Nov 18, 2015	-1.37% Sep 4, 2020 - Sep 22, 2020
#13	-14.71% Nov 3, 2011 - Dec 20, 2011	-1.33% Sep 13, 2021 - Sep 15, 2021
#14	-13.55% Aug 3, 2011 - Aug 17, 2011	-1.14% Apr 15, 2026 - Apr 17, 2026
#15	-13.09% Dec 13, 2018 - Feb 15, 2019	-0.94% Apr 17, 2026 - Apr 21, 2026