MEDX vs UUUG

Comparison between HORIZON KINETICS MEDICAL ETF (MEDX, ETF) and Leverage Shares 2X Long UUUU Daily ETF (UUUG, ETF).

MEDX vs UUUG - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	MEDX(ETF)	UUUG(ETF)
Net Assets	$18M	$18M
Expense Ratio	0.85%	N/A
Max Drawdown	24.64%	79.88%
Sharpe Ratio	1.43	-0.30
5Y Beta	0.52	5.82
P/E Ratio	149.38	N/A
Forward P/E	17.84	N/A
5Y EPS CAGR	5.73%	N/A
Debt to Equity	115.14%	N/A
P/S Ratio	5.25	N/A
P/B Ratio	5.54	N/A

Net Assets

MEDX

$18M

UUUG

$18M

Expense Ratio

MEDX

0.85%

UUUG

N/A

Max Drawdown

Winner

MEDX

24.64%

UUUG

79.88%

Sharpe Ratio

Winner

MEDX

1.43

UUUG

-0.30

5Y Beta

Winner

MEDX

0.52

UUUG

5.82

P/E Ratio

MEDX

149.38

UUUG

N/A

Forward P/E

MEDX

17.84

UUUG

N/A

5Y EPS CAGR

MEDX

5.73%

UUUG

N/A

Debt to Equity

MEDX

115.14%

UUUG

N/A

P/S Ratio

MEDX

5.25

UUUG

N/A

P/B Ratio

MEDX

5.54

UUUG

N/A

MEDX vs UUUG - Holdings Comparison

MEDX and UUUG have 0 common holdings. Overlap is 0.00%

MEDX's top 25 holdings weight is 98.21%. UUUG's top 25 holdings weight is 8.74%.

Rank	MEDX	UUUG
#1	ELI LILLY AND CO (LLY) - 17.17%	FIRST AMERICAN TREASURY OBLIGS X (FXFXX) - 8.74%
#2	ABBVIE INC (ABBV) - 8.32%	N/A
#3	US BANK MMDA USBGFS 7 (n/a) - 8.08%	N/A
#4	NOVARTIS AG ADR (NVS) - 7.40%	N/A
#5	JOHNSON & JOHNSON (JNJ) - 5.69%	N/A
#6	ASTRAZENECA PLC (AZN:XLON) - 5.46%	N/A
#7	BRISTOL-MYERS SQUIBB CO (BMY) - 4.97%	N/A
#8	IONIS PHARMACEUTICALS INC (IONS) - 4.68%	N/A
#9	ALKERMES PLC (ALKS) - 4.43%	N/A
#10	AMGEN INC (AMGN) - 3.96%	N/A
#11	MERCK & CO INC (MRK) - 3.91%	N/A
#12	ALNYLAM PHARMACEUTICALS INC (ALNY) - 3.67%	N/A
#13	PFIZER INC (PFE) - 3.39%	N/A
#14	BIOGEN INC (BIIB) - 3.10%	N/A
#15	GSK PLC ADR (GSK) - 2.93%	N/A
#16	CRISPR THERAPEUTICS AG (CRSP) - 2.65%	N/A
#17	REGENERON PHARMACEUTICALS INC (REGN) - 2.35%	N/A
#18	BEAM THERAPEUTICS INC (BEAM) - 1.33%	N/A
#19	INTELLIA THERAPEUTICS INC (NTLA) - 0.94%	N/A
#20	SANDOZ GROUP AG ADR (SDZNY) - 0.83%	N/A
#21	VANDA PHARMACEUTICALS INC (VNDA) - 0.81%	N/A
#22	HALEON PLC ADR (HLN) - 0.67%	N/A
#23	GALECTIN THERAPEUTICS INC (GALT) - 0.61%	N/A
#24	LANTERN PHARMA INC ORDINARY SHARES (LTRN) - 0.45%	N/A
#25	EDITAS MEDICINE INC (EDIT) - 0.41%	N/A
Total Holdings	34	1

MEDX vs UUUG - Historical Returns

Returns include dividend reinvestment.

Period	MEDX	UUUG
1 month	+5.47%	-53.74%
3 months	+1.80%	-56.03%
6 months	+4.19%	N/A
1 year	+32.32%	N/A
Max(CAGR)	+5.44%	-90.96%

Winner

MEDX

+5.47%

UUUG

-53.74%

Winner

MEDX

+1.80%

UUUG

-56.03%

MEDX

+4.19%

UUUG

N/A

MEDX

+32.32%

UUUG

N/A

Max(CAGR)

Winner

MEDX

+5.44%

UUUG

-90.96%

MEDX vs UUUG - Annual Returns (2023 - 2026)

Returns include dividend reinvestment.

Year	MEDX	UUUG
2026	+3.88%	-60.98%
2025	+27.78%	N/A
2024	-6.65%	N/A
2023	-6.24%	N/A

MEDX vs UUUG Drawdown Comparison

The maximum drawdown for MEDX was -23.10%, occurring on Apr 10, 2025. Recovery took 271 trading sessions.

The maximum drawdown for UUUG was -79.88%, occurring on Jun 5, 2026. This drawdown has not yet recovered.

The current MEDX drawdown is -2.74%. The current UUUG drawdown is -79.88%.

Rank	MEDX	UUUG
#1	-23.10% Aug 30, 2024 - Oct 1, 2025	-79.88% Jan 28, 2026 - Jun 5, 2026
#2	-15.48% May 10, 2023 - Feb 28, 2024	-16.57% Jan 23, 2026 - Jan 28, 2026
#3	-10.54% Feb 24, 2026 - Apr 29, 2026	-8.56% Jan 20, 2026 - Jan 22, 2026
#4	-10.25% Feb 28, 2024 - Jul 11, 2024	N/A
#5	-9.31% Feb 13, 2023 - May 5, 2023	N/A
#6	-5.24% Jul 16, 2024 - Aug 19, 2024	N/A
#7	-3.98% Jan 7, 2026 - Feb 4, 2026	N/A
#8	-3.88% Nov 26, 2025 - Jan 7, 2026	N/A
#9	-3.27% Oct 20, 2025 - Nov 11, 2025	N/A
#10	-2.11% Feb 4, 2026 - Feb 6, 2026	N/A
#11	-1.62% Oct 9, 2025 - Oct 20, 2025	N/A
#12	-1.61% Nov 18, 2025 - Nov 24, 2025	N/A
#13	-1.48% Jan 31, 2023 - Feb 13, 2023	N/A
#14	-1.43% Feb 6, 2026 - Feb 17, 2026	N/A
#15	-1.07% Feb 17, 2026 - Feb 23, 2026	N/A