MEDX vs TNXT
Comparison between HORIZON KINETICS MEDICAL ETF (MEDX, ETF) and T. ROWE PRICE INNOVATION LEADERS ETF (TNXT, ETF).
MEDX vs TNXT - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Net Assets
MEDX
$19M
TNXT
$19M
Expense Ratio
MEDX
0.85%
Winner
TNXT
0.49%
Max Drawdown
MEDX
24.64%
Winner
TNXT
12.97%
Sharpe Ratio
Winner
MEDX
1.33
TNXT
0.78
5Y Beta
Winner
MEDX
0.53
TNXT
1.44
P/E Ratio
MEDX
263.26
Winner
TNXT
64.22
Forward P/E
Winner
MEDX
18.85
TNXT
21.75
5Y EPS CAGR
MEDX
5.94%
Winner
TNXT
33.55%
Debt to Equity
MEDX
114.91%
TNXT
N/A
P/S Ratio
MEDX
5.41
Winner
TNXT
3.46
P/B Ratio
Winner
MEDX
5.62
TNXT
7.53
MEDX vs TNXT - Holdings Comparison
MEDX and TNXT have 6 common holdings. Overlap is 2.00%
MEDX's top 25 holdings weight is 98.18%. TNXT's top 25 holdings weight is 50.72%.
| Rank | MEDX | TNXT |
|---|---|---|
| #1 | ELI LILLY AND CO (LLY) - 18.13% | NVIDIA CORP (NVDA) - 8.20% |
| #2 | ABBVIE INC (ABBV) - 8.39% | APPLE INC (AAPL) - 5.03% |
| #3 | US BANK MMDA USBGFS 7 (n/a) - 7.96% | BROADCOM INC (AVGO) - 3.68% |
| #4 | NOVARTIS AG ADR (NVS) - 6.98% | AMAZON.COM INC (AMZN) - 3.43% |
| #5 | JOHNSON & JOHNSON (JNJ) - 5.43% | MICROSOFT CORP (MSFT) - 3.31% |
| #6 | ASTRAZENECA PLC (AZN:XLON) - 5.16% | ALPHABET INC CLASS A (GOOGL) - 2.59% |
| #7 | ALKERMES PLC (ALKS) - 4.83% | ADVANCED MICRO DEVICES INC (AMD) - 2.41% |
| #8 | BRISTOL-MYERS SQUIBB CO (BMY) - 4.63% | ALPHABET INC CLASS C (GOOG) - 2.37% |
| #9 | IONIS PHARMACEUTICALS INC (IONS) - 4.62% | STATE STREET INSTL US GOVT MMKT PREMIER (GVMXX) - 1.84% |
| #10 | MERCK & CO INC (MRK) - 3.94% | ELI LILLY AND CO (LLY) - 1.83% |
| #11 | AMGEN INC (AMGN) - 3.93% | META PLATFORMS INC CLASS A (META) - 1.80% |
| #12 | ALNYLAM PHARMACEUTICALS INC (ALNY) - 3.60% | TESLA INC (TSLA) - 1.79% |
| #13 | PFIZER INC (PFE) - 3.36% | INTEL CORP (INTC) - 1.76% |
| #14 | BIOGEN INC (BIIB) - 2.99% | MICRON TECHNOLOGY INC (MU) - 1.68% |
| #15 | GSK PLC ADR (GSK) - 2.80% | VISA INC CLASS A (V) - 1.37% |
| #16 | CRISPR THERAPEUTICS AG (CRSP) - 2.79% | n/a (TSM) - 1.29% |
| #17 | REGENERON PHARMACEUTICALS INC (REGN) - 2.20% | ORACLE CORP (ORCL) - 1.14% |
| #18 | BEAM THERAPEUTICS INC (BEAM) - 1.41% | QUALCOMM INC (QCOM) - 1.14% |
| #19 | INTELLIA THERAPEUTICS INC (NTLA) - 0.96% | MASTERCARD INC CLASS A (MA) - 1.10% |
| #20 | VANDA PHARMACEUTICALS INC (VNDA) - 0.81% | BLOCK INC CLASS A (XYZ) - 1.07% |
| #21 | SANDOZ GROUP AG ADR (SDZNY) - 0.78% | PALO ALTO NETWORKS INC (PANW) - 0.39% |
| #22 | GALECTIN THERAPEUTICS INC (GALT) - 0.66% | CORNING INC (GLW) - 0.38% |
| #23 | REPLIMUNE GROUP INC (REPL) - 0.65% | CADENCE DESIGN SYSTEMS INC (CDNS) - 0.38% |
| #24 | HALEON PLC ADR (HLN) - 0.62% | MURATA MANUFACTURING CO LTD (n/a) - 0.37% |
| #25 | LANTERN PHARMA INC ORDINARY SHARES (LTRN) - 0.55% | PARKER HANNIFIN CORP (PH) - 0.37% |
| Total Holdings | 35 | 225 |
MEDX vs TNXT - Historical Returns
Returns include dividend reinvestment.
1M
Winner
MEDX
+4.54%
TNXT
+0.19%
3M
MEDX
+3.19%
Winner
TNXT
+16.28%
6M
MEDX
+4.82%
TNXT
N/A
1Y
MEDX
+28.04%
TNXT
N/A
Max(CAGR)
MEDX
+5.41%
Winner
TNXT
+21.33%
MEDX vs TNXT - Annual Returns (2023 - 2026)
Returns include dividend reinvestment.
| Year | MEDX | TNXT |
|---|---|---|
| 2026 | +3.91% | +7.35% |
| 2025 | +27.78% | N/A |
| 2024 | -6.65% | N/A |
| 2023 | -6.24% | N/A |
MEDX vs TNXT Drawdown Comparison
The maximum drawdown for MEDX was -23.10%, occurring on Apr 10, 2025. Recovery took 271 trading sessions.
The maximum drawdown for TNXT was -12.97%, occurring on Mar 30, 2026. Recovery took 52 trading sessions.
The current MEDX drawdown is -2.71%. The current TNXT drawdown is -3.86%.
| Rank | MEDX | TNXT |
|---|---|---|
| #1 | -23.10% Aug 30, 2024 - Oct 1, 2025 | -12.97% Jan 29, 2026 - Apr 15, 2026 |
| #2 | -15.48% May 10, 2023 - Feb 28, 2024 | -6.43% Jun 1, 2026 - Jun 10, 2026 |
| #3 | -10.54% Feb 24, 2026 - Apr 29, 2026 | -3.00% May 14, 2026 - May 26, 2026 |
| #4 | -10.25% Feb 28, 2024 - Jul 11, 2024 | -1.31% Apr 24, 2026 - May 1, 2026 |
| #5 | -9.31% Feb 13, 2023 - May 5, 2023 | -1.19% Apr 17, 2026 - Apr 24, 2026 |
| #6 | -5.24% Jul 16, 2024 - Aug 19, 2024 | -0.65% May 11, 2026 - May 13, 2026 |
| #7 | -3.98% Jan 7, 2026 - Feb 4, 2026 | -0.61% May 6, 2026 - May 8, 2026 |
| #8 | -3.88% Nov 26, 2025 - Jan 7, 2026 | -0.29% May 28, 2026 - Jun 1, 2026 |
| #9 | -3.27% Oct 20, 2025 - Nov 11, 2025 | N/A |
| #10 | -2.11% Feb 4, 2026 - Feb 6, 2026 | N/A |
| #11 | -1.62% Oct 9, 2025 - Oct 20, 2025 | N/A |
| #12 | -1.61% Nov 18, 2025 - Nov 24, 2025 | N/A |
| #13 | -1.48% Jan 31, 2023 - Feb 13, 2023 | N/A |
| #14 | -1.43% Feb 6, 2026 - Feb 17, 2026 | N/A |
| #15 | -1.07% Feb 17, 2026 - Feb 23, 2026 | N/A |
Correlation
Correlation between MEDX and TNXT is 0.18 which considered as a very weak or no correlation - the stocks move independently of each other.
0.18
-101
Select Stocks to Compare
Popular: MEDX vs SPYTNXT vs SPY
More Comparisons
Compare with similar stocks