MEDX vs CPSP

Comparison between HORIZON KINETICS MEDICAL ETF (MEDX, ETF) and Calamos S&P 500 Structured Alt Protection ETF April (CPSP, ETF).

MEDX vs CPSP - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	MEDX(ETF)	CPSP(ETF)
Net Assets	$19M	$19M
Expense Ratio	0.85%	0.69%
Max Drawdown	24.64%	1.73%
Sharpe Ratio	1.33	2.09
5Y Beta	0.53	0.11
P/E Ratio	263.26	N/A
Forward P/E	18.85	N/A
5Y EPS CAGR	5.94%	N/A
Debt to Equity	114.91%	N/A
P/S Ratio	5.41	N/A
P/B Ratio	5.62	N/A

Net Assets

MEDX

$19M

Winner

CPSP

$19M

Expense Ratio

MEDX

0.85%

Winner

CPSP

0.69%

Max Drawdown

MEDX

24.64%

Winner

CPSP

1.73%

Sharpe Ratio

MEDX

1.33

Winner

CPSP

2.09

5Y Beta

MEDX

0.53

Winner

CPSP

0.11

P/E Ratio

MEDX

263.26

CPSP

N/A

Forward P/E

MEDX

18.85

CPSP

N/A

5Y EPS CAGR

MEDX

5.94%

CPSP

N/A

Debt to Equity

MEDX

114.91%

CPSP

N/A

P/S Ratio

MEDX

5.41

CPSP

N/A

P/B Ratio

MEDX

5.62

CPSP

N/A

MEDX vs CPSP - Historical Returns

Returns include dividend reinvestment.

Period	MEDX	CPSP
1 month	+4.54%	+0.24%
3 months	+3.19%	+2.13%
6 months	+4.82%	+3.47%
1 year	+28.04%	+6.63%
Max(CAGR)	+5.41%	+7.20%

Winner

MEDX

+4.54%

CPSP

+0.24%

Winner

MEDX

+3.19%

CPSP

+2.13%

Winner

MEDX

+4.82%

CPSP

+3.47%

Winner

MEDX

+28.04%

CPSP

+6.63%

Max(CAGR)

MEDX

+5.41%

Winner

CPSP

+7.20%

MEDX vs CPSP - Annual Returns (2023 - 2026)

Returns include dividend reinvestment.

Year	MEDX	CPSP
2026	+3.91%	+2.99%
2025	+27.78%	+5.46%
2024	-6.65%	N/A
2023	-6.24%	N/A

MEDX vs CPSP Drawdown Comparison

The maximum drawdown for MEDX was -23.10%, occurring on Apr 10, 2025. Recovery took 271 trading sessions.

The maximum drawdown for CPSP was -1.73%, occurring on Apr 8, 2025. Recovery took 18 trading sessions.

The current MEDX drawdown is -2.71%. The current CPSP drawdown is -0.24%.

Rank	MEDX	CPSP
#1	-23.10% Aug 30, 2024 - Oct 1, 2025	-1.73% Apr 2, 2025 - Apr 29, 2025
#2	-15.48% May 10, 2023 - Feb 28, 2024	-0.38% May 16, 2025 - May 30, 2025
#3	-10.54% Feb 24, 2026 - Apr 29, 2026	-0.37% Nov 11, 2025 - Nov 25, 2025
#4	-10.25% Feb 28, 2024 - Jul 11, 2024	-0.36% Jun 12, 2025 - Jun 23, 2025
#5	-9.31% Feb 13, 2023 - May 5, 2023	-0.30% Jun 4, 2026 - Jun 10, 2026
#6	-5.24% Jul 16, 2024 - Aug 19, 2024	-0.25% Aug 13, 2025 - Aug 22, 2025
#7	-3.98% Jan 7, 2026 - Feb 4, 2026	-0.23% Oct 6, 2025 - Oct 20, 2025
#8	-3.88% Nov 26, 2025 - Jan 7, 2026	-0.17% Oct 27, 2025 - Nov 10, 2025
#9	-3.27% Oct 20, 2025 - Nov 11, 2025	-0.16% Jul 25, 2025 - Aug 4, 2025
#10	-2.11% Feb 4, 2026 - Feb 6, 2026	-0.16% Aug 27, 2025 - Sep 4, 2025
#11	-1.62% Oct 9, 2025 - Oct 20, 2025	-0.16% Sep 15, 2025 - Sep 17, 2025
#12	-1.61% Nov 18, 2025 - Nov 24, 2025	-0.15% Mar 4, 2026 - Mar 10, 2026
#13	-1.48% Jan 31, 2023 - Feb 13, 2023	-0.15% May 14, 2026 - May 26, 2026
#14	-1.43% Feb 6, 2026 - Feb 17, 2026	-0.14% Oct 21, 2025 - Oct 24, 2025
#15	-1.07% Feb 17, 2026 - Feb 23, 2026	-0.13% Feb 2, 2026 - Feb 6, 2026