LYEL vs CCCC

Comparison between Lyell Immunopharma Inc (LYEL, Company) and C4 Therapeutics Inc (CCCC, Company).

Both LYEL and CCCC are from the Healthcare sector.

5-Year PerformanceCCCC has outperformed LYEL, delivering a return of -37.1% compared to -49.0%

LYEL vs CCCC - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	LYEL(COMPANY)	CCCC(COMPANY)
Market Cap	$390M	$389M
Max Drawdown	97.83%	97.82%
Sharpe Ratio	0.24	1.34
5Y Beta	1.46	1.85
Industry	Biotechnology	Biotechnology
P/E Ratio	-1.33	-2.98
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-34.44%	-24.68%
P/S Ratio	12668.15	11.75
P/B Ratio	1.44	1.76

Market Cap

Winner

LYEL

$390M

CCCC

$389M

Max Drawdown

LYEL

97.83%

Winner

CCCC

97.82%

Sharpe Ratio

LYEL

0.24

Winner

CCCC

1.34

5Y Beta

Winner

LYEL

1.46

CCCC

1.85

Industry

LYEL

Biotechnology

CCCC

Biotechnology

P/E Ratio

LYEL

-1.33

Winner

CCCC

-2.98

Debt to Equity

LYEL

0.00%

CCCC

0.00%

Free Cash Flow Yield

LYEL

-34.44%

Winner

CCCC

-24.68%

P/S Ratio

LYEL

12668.15

Winner

CCCC

11.75

P/B Ratio

Winner

LYEL

1.44

CCCC

1.76

LYEL vs CCCC - Historical Returns

Returns include dividend reinvestment.

Period	LYEL	CCCC
1 month	-41.95%	+29.63%
3 months	-45.71%	+27.06%
6 months	-52.59%	+44.19%
1 year	+4.45%	+161.90%
5 years(CAGR)	-48.96%	-37.07%
Max(CAGR)	-48.96%	-28.34%

LYEL

-41.95%

Winner

CCCC

+29.63%

LYEL

-45.71%

Winner

CCCC

+27.06%

LYEL

-52.59%

Winner

CCCC

+44.19%

LYEL

+4.45%

Winner

CCCC

+161.90%

5Y(CAGR)

LYEL

-48.96%

Winner

CCCC

-37.07%

Max(CAGR)

LYEL

-48.96%

Winner

CCCC

-28.34%

LYEL vs CCCC - Annual Returns (2020 - 2026)

Returns include dividend reinvestment.

Year	LYEL	CCCC
2026	-58.70%	+99.48%
2025	+138.60%	-47.81%
2024	-69.67%	-44.79%
2023	-42.26%	-11.44%
2022	-54.94%	-82.24%
2021	-54.17%	+0.75%
2020	N/A	+29.97%

LYEL vs CCCC Drawdown Comparison

The maximum drawdown for LYEL was -97.83%, occurring on May 14, 2025. This drawdown has not yet recovered.

The maximum drawdown for CCCC was -97.82%, occurring on Apr 16, 2025. This drawdown has not yet recovered.

The current LYEL drawdown is -96.67%. The current CCCC drawdown is -92.38%.

Rank	LYEL	CCCC
#1	-97.83% Sep 10, 2021 - May 14, 2025	-97.82% Sep 23, 2021 - Apr 16, 2025
#2	-20.11% Jul 16, 2021 - Sep 7, 2021	-34.65% Feb 10, 2021 - Sep 7, 2021
#3	-9.71% Jun 17, 2021 - Jul 16, 2021	-19.07% Nov 27, 2020 - Dec 23, 2020
#4	-1.11% Sep 8, 2021 - Sep 10, 2021	-15.43% Oct 6, 2020 - Oct 20, 2020
#5	N/A	-13.74% Dec 23, 2020 - Jan 11, 2021
#6	N/A	-13.38% Jan 25, 2021 - Feb 2, 2021
#7	N/A	-9.71% Oct 21, 2020 - Nov 16, 2020
#8	N/A	-6.78% Jan 13, 2021 - Jan 22, 2021
#9	N/A	-2.80% Jan 11, 2021 - Jan 13, 2021
#10	N/A	-2.56% Sep 17, 2021 - Sep 21, 2021
#11	N/A	-2.54% Feb 2, 2021 - Feb 5, 2021
#12	N/A	-2.44% Feb 5, 2021 - Feb 10, 2021
#13	N/A	-1.93% Sep 13, 2021 - Sep 17, 2021
#14	N/A	-1.83% Nov 17, 2020 - Nov 24, 2020
#15	N/A	-0.93% Sep 7, 2021 - Sep 9, 2021