LXRX vs TBPH

Comparison between Lexicon Pharmaceuticals Inc (LXRX, Company) and Theravance Biopharma Inc (TBPH, Company).

Both LXRX and TBPH are from the Healthcare sector.

5-Year PerformanceTBPH has outperformed LXRX, delivering a return of -1.0% compared to -14.4%

LXRX vs TBPH - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	LXRX(COMPANY)	TBPH(COMPANY)
Market Cap	$856M	$854M
Max Drawdown	99.91%	84.09%
Sharpe Ratio	1.59	1.12
5Y Beta	1.14	0.56
Industry	Biotechnology	Biotechnology
P/E Ratio	-28.37	12.01
Forward P/E	N/A	7.81
Debt to Equity	24.49%	0.00%
Free Cash Flow Yield	-4.53%	31.47%

Market Cap

Winner

LXRX

$856M

TBPH

$854M

Max Drawdown

LXRX

99.91%

Winner

TBPH

84.09%

Sharpe Ratio

Winner

LXRX

1.59

TBPH

1.12

5Y Beta

LXRX

1.14

Winner

TBPH

0.56

Industry

LXRX

Biotechnology

TBPH

Biotechnology

P/E Ratio

Winner

LXRX

-28.37

TBPH

12.01

Forward P/E

LXRX

N/A

TBPH

7.81

Debt to Equity

LXRX

24.49%

Winner

TBPH

0.00%

Free Cash Flow Yield

LXRX

-4.53%

Winner

TBPH

31.47%

LXRX vs TBPH - Historical Returns

Returns include dividend reinvestment.

Period	LXRX	TBPH
1 month	-0.46%	+1.16%
3 months	+31.10%	+12.27%
6 months	+76.23%	-11.96%
1 year	+192.88%	+56.67%
5 years(CAGR)	-14.41%	-1.04%
10 years(CAGR)	-16.69%	-3.19%
Max(CAGR)	-14.52%	-2.66%

LXRX

-0.46%

Winner

TBPH

+1.16%

Winner

LXRX

+31.10%

TBPH

+12.27%

Winner

LXRX

+76.23%

TBPH

-11.96%

Winner

LXRX

+192.88%

TBPH

+56.67%

5Y(CAGR)

LXRX

-14.41%

Winner

TBPH

-1.04%

10Y(CAGR)

LXRX

-16.69%

Winner

TBPH

-3.19%

Max(CAGR)

LXRX

-14.52%

Winner

TBPH

-2.66%

LXRX vs TBPH - Annual Returns (2000 - 2026)

Returns include dividend reinvestment.

Year	LXRX	TBPH
2026	+88.60%	-8.76%
2025	+47.99%	+101.62%
2024	-53.55%	-18.81%
2023	-23.12%	+2.46%
2022	-50.90%	-8.63%
2021	+11.93%	-36.97%
2020	-16.38%	-27.97%
2019	-39.94%	-1.11%
2018	-34.39%	-8.84%
2017	-30.42%	-14.18%
2016	+5.17%	+96.31%
2015	+105.98%	+11.50%
2014	-49.17%	-35.02%
2013	-24.41%	N/A
2012	+76.80%	N/A
2011	-14.00%	N/A
2010	-16.76%	N/A
2009	+18.06%	N/A
2008	-54.10%	N/A
2007	-17.89%	N/A
2006	-5.25%	N/A
2005	-50.68%	N/A
2004	+28.18%	N/A
2003	+14.37%	N/A
2002	-57.69%	N/A
2001	-17.57%	N/A
2000	-11.31%	N/A

LXRX vs TBPH Drawdown Comparison

The maximum drawdown for LXRX was -99.91%, occurring on Mar 3, 2025. This drawdown has not yet recovered.

The maximum drawdown for TBPH was -84.09%, occurring on Sep 15, 2021. This drawdown has not yet recovered.

The current LXRX drawdown is -99.35%. The current TBPH drawdown is -61.09%.

Rank	LXRX	TBPH
#1	-99.91% Jul 21, 2000 - Mar 3, 2025	-84.09% Jun 22, 2017 - Sep 15, 2021
#2	-51.33% Apr 7, 2000 - Jun 20, 2000	-68.80% Jun 23, 2014 - Sep 20, 2016
#3	-15.33% Jul 10, 2000 - Jul 20, 2000	-36.31% Oct 10, 2016 - Apr 19, 2017
#4	-8.08% Jun 21, 2000 - Jun 23, 2000	-15.07% May 16, 2014 - Jun 3, 2014
#5	-5.17% Jun 28, 2000 - Jul 5, 2000	-12.76% May 1, 2017 - Jun 22, 2017
#6	N/A	-6.81% Jun 16, 2014 - Jun 20, 2014
#7	N/A	-4.84% Sep 27, 2016 - Oct 5, 2016
#8	N/A	-2.76% Oct 5, 2016 - Oct 10, 2016
#9	N/A	-2.19% Sep 22, 2016 - Sep 27, 2016
#10	N/A	-1.03% Apr 26, 2017 - May 1, 2017
#11	N/A	-0.94% Apr 20, 2017 - Apr 24, 2017