LXRX vs JANX

Comparison between Lexicon Pharmaceuticals Inc (LXRX, Company) and Janux Therapeutics Inc (JANX, Company).

Both LXRX and JANX are from the Healthcare sector.

5-Year PerformanceJANX has outperformed LXRX, delivering a return of -11.6% compared to -17.0%

LXRX vs JANX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	LXRX(COMPANY)	JANX(COMPANY)
Market Cap	$800M	$800M
Max Drawdown	99.91%	83.14%
Sharpe Ratio	1.54	-0.45
5Y Beta	1.15	1.25
Industry	Biotechnology	Biotechnology
P/E Ratio	-26.53	-6.90
PEG Ratio	-0.14	-0.19
Debt to Equity	24.49%	0.00%
Free Cash Flow Yield	-4.85%	-9.81%
P/S Ratio	11.99	58.53
P/B Ratio	4.12	0.85

Market Cap

LXRX

$800M

Winner

JANX

$800M

Max Drawdown

LXRX

99.91%

Winner

JANX

83.14%

Sharpe Ratio

Winner

LXRX

1.54

JANX

-0.45

5Y Beta

Winner

LXRX

1.15

JANX

1.25

Industry

LXRX

Biotechnology

JANX

Biotechnology

P/E Ratio

Winner

LXRX

-26.53

JANX

-6.90

PEG Ratio

LXRX

-0.14

Winner

JANX

-0.19

Debt to Equity

LXRX

24.49%

Winner

JANX

0.00%

Free Cash Flow Yield

Winner

LXRX

-4.85%

JANX

-9.81%

P/S Ratio

Winner

LXRX

11.99

JANX

58.53

P/B Ratio

LXRX

4.12

Winner

JANX

0.85

LXRX vs JANX - Historical Returns

Returns include dividend reinvestment.

Period	LXRX	JANX
1 month	-20.33%	-5.90%
3 months	+11.63%	-2.76%
6 months	+47.69%	-11.37%
1 year	+175.94%	-46.95%
5 years(CAGR)	-16.98%	-11.62%
10 years(CAGR)	-18.40%	N/A
Max(CAGR)	-14.90%	-11.62%

LXRX

-20.33%

Winner

JANX

-5.90%

Winner

LXRX

+11.63%

JANX

-2.76%

Winner

LXRX

+47.69%

JANX

-11.37%

Winner

LXRX

+175.94%

JANX

-46.95%

5Y(CAGR)

LXRX

-16.98%

Winner

JANX

-11.62%

10Y(CAGR)

LXRX

-18.40%

JANX

N/A

Max(CAGR)

LXRX

-14.90%

Winner

JANX

-11.62%

LXRX vs JANX - Annual Returns (2000 - 2026)

Returns include dividend reinvestment.

Year	LXRX	JANX
2026	+68.42%	-0.66%
2025	+47.99%	-74.08%
2024	-53.55%	+385.84%
2023	-23.12%	-23.47%
2022	-50.90%	-34.93%
2021	+11.93%	-21.55%
2020	-16.38%	N/A
2019	-39.94%	N/A
2018	-34.39%	N/A
2017	-30.42%	N/A
2016	+5.17%	N/A
2015	+105.98%	N/A
2014	-49.17%	N/A
2013	-24.41%	N/A
2012	+76.80%	N/A
2011	-14.00%	N/A
2010	-16.76%	N/A
2009	+18.06%	N/A
2008	-54.10%	N/A
2007	-17.89%	N/A
2006	-5.25%	N/A
2005	-50.68%	N/A
2004	+28.18%	N/A
2003	+14.37%	N/A
2002	-57.69%	N/A
2001	-17.57%	N/A
2000	-11.31%	N/A

LXRX vs JANX Drawdown Comparison

The maximum drawdown for LXRX was -99.91%, occurring on Mar 3, 2025. This drawdown has not yet recovered.

The maximum drawdown for JANX was -83.14%, occurring on Nov 9, 2023. Recovery took 643 trading sessions.

The current LXRX drawdown is -99.42%. The current JANX drawdown is -79.71%.

Rank	LXRX	JANX
#1	-99.91% Jul 21, 2000 - Mar 3, 2025	-83.14% Aug 5, 2021 - Feb 27, 2024
#2	-51.33% Apr 7, 2000 - Jun 20, 2000	-81.78% Dec 4, 2024 - Feb 5, 2026
#3	-15.33% Jul 10, 2000 - Jul 20, 2000	-45.52% May 3, 2024 - Dec 4, 2024
#4	-8.08% Jun 21, 2000 - Jun 23, 2000	-29.41% Feb 27, 2024 - Apr 11, 2024
#5	-5.17% Jun 28, 2000 - Jul 5, 2000	-26.12% Jun 11, 2021 - Jun 29, 2021
#6	N/A	-10.54% Apr 12, 2024 - Apr 29, 2024
#7	N/A	-9.54% Jul 23, 2021 - Jul 29, 2021
#8	N/A	-4.25% Jul 9, 2021 - Jul 20, 2021
#9	N/A	-3.03% Aug 2, 2021 - Aug 5, 2021
#10	N/A	-1.66% Jun 29, 2021 - Jul 2, 2021
#11	N/A	-1.65% Jul 7, 2021 - Jul 9, 2021