LVTX vs KPTI

Comparison between LAVA Therapeutics NV (LVTX, Company) and Karyopharm Therapeutics Inc (KPTI, Company).

Both LVTX and KPTI are from the Healthcare sector.

5-Year PerformanceLVTX has outperformed KPTI, delivering a return of -36.1% compared to -51.0%

LVTX vs KPTI - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	LVTX(COMPANY)	KPTI(COMPANY)
Market Cap	$46M	$46M
Max Drawdown	94.34%	99.74%
Sharpe Ratio	0.31	-0.25
5Y Beta	N/A	0.75
Industry	Biotechnology	Biotechnology
P/E Ratio	-1.97	-0.14
PEG Ratio	N/A	-0.00
5Y EPS CAGR	N/A	-18.43%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-67.20%	N/A
P/S Ratio	N/A	0.30
P/B Ratio	N/A	12.05

Market Cap

Winner

LVTX

$46M

KPTI

$46M

Max Drawdown

Winner

LVTX

94.34%

KPTI

99.74%

Sharpe Ratio

Winner

LVTX

0.31

KPTI

-0.25

5Y Beta

LVTX

N/A

KPTI

0.75

Industry

LVTX

Biotechnology

KPTI

Biotechnology

P/E Ratio

Winner

LVTX

-1.97

KPTI

-0.14

PEG Ratio

LVTX

N/A

KPTI

-0.00

5Y EPS CAGR

LVTX

N/A

KPTI

-18.43%

Debt to Equity

LVTX

0.00%

KPTI

0.00%

Free Cash Flow Yield

LVTX

-67.20%

KPTI

N/A

P/S Ratio

LVTX

N/A

KPTI

0.30

P/B Ratio

LVTX

N/A

KPTI

12.05

LVTX vs KPTI - Historical Returns

Returns include dividend reinvestment.

Period	LVTX	KPTI
1 month	+7.74%	-75.08%
3 months	+10.83%	-75.68%
6 months	+33.85%	-79.73%
1 year	+3.57%	-67.44%
5 years(CAGR)	-36.13%	-50.99%
10 years(CAGR)	N/A	-33.54%
Max(CAGR)	-36.13%	-31.35%

Winner

LVTX

+7.74%

KPTI

-75.08%

Winner

LVTX

+10.83%

KPTI

-75.68%

Winner

LVTX

+33.85%

KPTI

-79.73%

Winner

LVTX

+3.57%

KPTI

-67.44%

5Y(CAGR)

Winner

LVTX

-36.13%

KPTI

-50.99%

10Y(CAGR)

LVTX

N/A

KPTI

-33.54%

Max(CAGR)

LVTX

-36.13%

Winner

KPTI

-31.35%

LVTX vs KPTI - Annual Returns (2013 - 2026)

Returns include dividend reinvestment.

Year	LVTX	KPTI
2026	N/A	-72.74%
2025	+68.93%	-39.54%
2024	-45.75%	-24.96%
2023	-56.11%	-73.47%
2022	-41.76%	-52.11%
2021	-61.54%	-62.00%
2020	N/A	-17.31%
2019	N/A	+100.52%
2018	N/A	-5.54%
2017	N/A	-0.41%
2016	N/A	-30.16%
2015	N/A	-65.12%
2014	N/A	+62.67%
2013	N/A	+42.80%

LVTX vs KPTI Drawdown Comparison

The maximum drawdown for LVTX was -94.34%, occurring on Feb 11, 2025. This drawdown has not yet recovered.

The maximum drawdown for KPTI was -99.74%, occurring on Aug 17, 2026. This drawdown has not yet recovered.

The current LVTX drawdown is -89.13%. The current KPTI drawdown is -99.72%.

Rank	LVTX	KPTI
#1	-94.34% Apr 13, 2021 - Feb 11, 2025	-99.74% Jun 13, 2014 - Aug 17, 2026
#2	-14.42% Mar 31, 2021 - Apr 6, 2021	-43.74% Mar 6, 2014 - Jun 13, 2014
#3	-12.59% Mar 25, 2021 - Mar 31, 2021	-10.42% Dec 20, 2013 - Jan 15, 2014
#4	-4.89% Apr 6, 2021 - Apr 13, 2021	-9.08% Jan 31, 2014 - Feb 12, 2014
#5	N/A	-8.83% Mar 4, 2014 - Mar 6, 2014
#6	N/A	-5.88% Jan 22, 2014 - Jan 30, 2014
#7	N/A	-4.87% Feb 27, 2014 - Mar 4, 2014
#8	N/A	-4.36% Feb 13, 2014 - Feb 20, 2014
#9	N/A	-3.39% Dec 9, 2013 - Dec 13, 2013
#10	N/A	-1.60% Nov 29, 2013 - Dec 6, 2013
#11	N/A	-1.48% Nov 8, 2013 - Nov 29, 2013
#12	N/A	-0.44% Nov 6, 2013 - Nov 8, 2013