LIXT vs SERA

Comparison between Lixte Biotechnology Holdings Inc (LIXT, Company) and Sera Prognostics Inc Class A (SERA, Company).

Both LIXT and SERA are from the Healthcare sector.

5-Year PerformanceLIXT has outperformed SERA, delivering a return of -23.7% compared to -31.4%

LIXT vs SERA - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	LIXT(COMPANY)	SERA(COMPANY)
Market Cap	$89M	$88M
Max Drawdown	99.12%	91.10%
Sharpe Ratio	2.11	0.48
5Y Beta	0.62	1.02
Industry	Biotechnology	Medical Devices
P/E Ratio	-6.94	-2.56
PEG Ratio	0.00	N/A
5Y EPS CAGR	24.68%	N/A
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-4.90%	-31.35%
P/S Ratio	20.35	1202.24
P/B Ratio	16.61	1.07

Market Cap

Winner

LIXT

$89M

SERA

$88M

Max Drawdown

LIXT

99.12%

Winner

SERA

91.10%

Sharpe Ratio

Winner

LIXT

2.11

SERA

0.48

5Y Beta

Winner

LIXT

0.62

SERA

1.02

Industry

LIXT

Biotechnology

SERA

Medical Devices

P/E Ratio

Winner

LIXT

-6.94

SERA

-2.56

PEG Ratio

LIXT

0.00

SERA

N/A

5Y EPS CAGR

LIXT

24.68%

SERA

N/A

Debt to Equity

LIXT

0.00%

SERA

0.00%

Free Cash Flow Yield

Winner

LIXT

-4.90%

SERA

-31.35%

P/S Ratio

Winner

LIXT

20.35

SERA

1202.24

P/B Ratio

LIXT

16.61

Winner

SERA

1.07

LIXT vs SERA - Historical Returns

Returns include dividend reinvestment.

Period	LIXT	SERA
1 month	+27.21%	-10.63%
3 months	+181.20%	+1.65%
6 months	+79.38%	-48.61%
1 year	+849.72%	-1.07%
5 years(CAGR)	-23.69%	-31.41%
10 years(CAGR)	-4.62%	N/A
Max(CAGR)	-6.17%	-31.41%

Winner

LIXT

+27.21%

SERA

-10.63%

Winner

LIXT

+181.20%

SERA

+1.65%

Winner

LIXT

+79.38%

SERA

-48.61%

Winner

LIXT

+849.72%

SERA

-1.07%

5Y(CAGR)

Winner

LIXT

-23.69%

SERA

-31.41%

10Y(CAGR)

LIXT

-4.62%

SERA

N/A

Max(CAGR)

Winner

LIXT

-6.17%

SERA

-31.41%

LIXT vs SERA - Annual Returns (2010 - 2026)

Returns include dividend reinvestment.

Year	LIXT	SERA
2026	+94.79%	-38.33%
2025	+77.03%	-64.59%
2024	-11.37%	+36.35%
2023	-53.68%	+356.49%
2022	-60.85%	-83.57%
2021	-62.93%	-42.27%
2020	-37.84%	N/A
2019	-27.66%	N/A
2018	+447.35%	N/A
2017	+37.50%	N/A
2016	-68.87%	N/A
2015	+22.92%	N/A
2014	+20.00%	N/A
2013	-48.00%	N/A
2012	-50.00%	N/A
2011	-20.63%	N/A
2010	+80.00%	N/A

LIXT vs SERA Drawdown Comparison

The maximum drawdown for LIXT was -99.12%, occurring on Jun 27, 2025. This drawdown has not yet recovered.

The maximum drawdown for SERA was -91.10%, occurring on Dec 28, 2022. This drawdown has not yet recovered.

The current LIXT drawdown is -90.77%. The current SERA drawdown is -85.81%.

Rank	LIXT	SERA
#1	-99.12% Aug 26, 2019 - Jun 27, 2025	-91.10% Aug 9, 2021 - Dec 28, 2022
#2	-90.82% Apr 4, 2011 - Aug 22, 2018	-23.11% Jul 15, 2021 - Aug 2, 2021
#3	-88.00% May 19, 2010 - Sep 20, 2010	-8.00% Aug 2, 2021 - Aug 5, 2021
#4	-49.00% Aug 22, 2018 - Oct 12, 2018	N/A
#5	-46.15% Nov 1, 2018 - Aug 22, 2019	N/A
#6	-25.93% Oct 12, 2018 - Oct 18, 2018	N/A
#7	-20.00% Feb 14, 2011 - Mar 17, 2011	N/A
#8	-18.75% Oct 18, 2018 - Nov 1, 2018	N/A
#9	-2.26% Aug 22, 2019 - Aug 26, 2019	N/A