KPTI vs OMI

Comparison between Karyopharm Therapeutics Inc (KPTI, Company) and Owens & Minor Inc (OMI, Company).

Both KPTI and OMI are from the Healthcare sector.

5-Year PerformanceOMI has outperformed KPTI, delivering a return of -36.5% compared to -43.8%

KPTI vs OMI - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	KPTI(COMPANY)	OMI(COMPANY)
Market Cap	$215M	$214M
Max Drawdown	99.50%	94.89%
Sharpe Ratio	1.17	-1.24
5Y Beta	0.81	0.98
Industry	Biotechnology	Medical Distribution
P/E Ratio	-0.65	-0.20
Forward P/E	N/A	3.32
PEG Ratio	-0.01	-0.00
5Y Dividends CAGR	N/A	-58.54%
5Y EPS CAGR	-18.43%	N/A
Debt to Equity	0.00%	-125.06%
Free Cash Flow Yield	-27.51%	-92.12%
P/S Ratio	1.50	N/A
P/B Ratio	12.05	N/A

Market Cap

Winner

KPTI

$215M

OMI

$214M

Max Drawdown

KPTI

99.50%

Winner

OMI

94.89%

Sharpe Ratio

Winner

KPTI

1.17

OMI

-1.24

5Y Beta

Winner

KPTI

0.81

OMI

0.98

Industry

KPTI

Biotechnology

OMI

Medical Distribution

P/E Ratio

Winner

KPTI

-0.65

OMI

-0.20

Forward P/E

KPTI

N/A

OMI

3.32

PEG Ratio

Winner

KPTI

-0.01

OMI

-0.00

5Y Dividends CAGR

KPTI

N/A

OMI

-58.54%

5Y EPS CAGR

KPTI

-18.43%

OMI

N/A

Debt to Equity

KPTI

0.00%

Winner

OMI

-125.06%

Free Cash Flow Yield

Winner

KPTI

-27.51%

OMI

-92.12%

P/S Ratio

KPTI

1.50

OMI

N/A

P/B Ratio

KPTI

12.05

OMI

N/A

KPTI vs OMI - Historical Returns

Returns include dividend reinvestment.

Period	KPTI	OMI
1 month	-12.61%	+4.87%
3 months	-14.23%	-44.22%
6 months	+24.45%	-70.28%
1 year	+95.65%	-78.58%
5 years(CAGR)	-43.81%	-36.47%
10 years(CAGR)	-22.98%	-21.53%
Max(CAGR)	-23.61%	-0.90%

KPTI

-12.61%

Winner

OMI

+4.87%

Winner

KPTI

-14.23%

OMI

-44.22%

Winner

KPTI

+24.45%

OMI

-70.28%

Winner

KPTI

+95.65%

OMI

-78.58%

5Y(CAGR)

KPTI

-43.81%

Winner

OMI

-36.47%

10Y(CAGR)

KPTI

-22.98%

Winner

OMI

-21.53%

Max(CAGR)

KPTI

-23.61%

Winner

OMI

-0.90%

KPTI vs OMI - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	KPTI	OMI
2026	+9.39%	N/A
2025	-39.54%	-78.21%
2024	-24.96%	-32.10%
2023	-73.47%	-1.68%
2022	-52.11%	-56.04%
2021	-62.00%	+52.14%
2020	-17.31%	+423.82%
2019	+100.52%	-20.41%
2018	-5.54%	-65.35%
2017	-0.41%	-45.98%
2016	-30.16%	+2.51%
2015	-65.12%	+6.13%
2014	+62.67%	-0.17%
2013	+42.80%	+28.92%
2012	N/A	+4.67%
2011	N/A	-3.44%
2010	N/A	+4.47%
2009	N/A	+15.97%
2008	N/A	-8.81%
2007	N/A	+38.19%
2006	N/A	+12.25%
2005	N/A	-0.77%
2004	N/A	+27.37%
2003	N/A	+33.28%
2002	N/A	-7.71%
2001	N/A	+8.11%
2000	N/A	+109.69%
1999	N/A	+3.61%

KPTI vs OMI Drawdown Comparison

The maximum drawdown for KPTI was -99.50%, occurring on Apr 1, 2025. This drawdown has not yet recovered.

The maximum drawdown for OMI was -94.89%, occurring on Dec 9, 2025. This drawdown has not yet recovered.

The current KPTI drawdown is -98.89%. The current OMI drawdown is -94.25%.

Rank	KPTI	OMI
#1	-99.50% Jun 13, 2014 - Apr 1, 2025	-94.89% Jun 8, 2021 - Dec 9, 2025
#2	-43.74% Mar 6, 2014 - Jun 13, 2014	-93.24% Apr 19, 2016 - Mar 10, 2021
#3	-10.42% Dec 20, 2013 - Jan 15, 2014	-37.15% Jul 17, 2008 - Apr 6, 2010
#4	-9.08% Jan 31, 2014 - Feb 12, 2014	-35.14% May 3, 2002 - May 28, 2003
#5	-8.83% Mar 4, 2014 - Mar 6, 2014	-29.71% Jul 18, 2000 - Dec 27, 2000
#6	-5.88% Jan 22, 2014 - Jan 30, 2014	-25.93% Oct 14, 2003 - Jul 29, 2004
#7	-4.87% Feb 27, 2014 - Mar 4, 2014	-24.63% Jul 7, 2011 - May 10, 2013
#8	-4.36% Feb 13, 2014 - Feb 20, 2014	-20.82% Apr 23, 2021 - May 26, 2021
#9	-3.39% Dec 9, 2013 - Dec 13, 2013	-20.28% Dec 28, 2000 - Apr 25, 2001
#10	-1.60% Nov 29, 2013 - Dec 6, 2013	-19.94% Jan 11, 2000 - Feb 22, 2000
#11	-1.48% Nov 8, 2013 - Nov 29, 2013	-19.17% Apr 23, 2010 - Mar 28, 2011
#12	-0.44% Nov 6, 2013 - Nov 8, 2013	-19.06% Apr 18, 2006 - Feb 20, 2007
#13	N/A	-17.49% Jul 20, 2005 - Mar 16, 2006
#14	N/A	-17.37% Aug 29, 2001 - May 3, 2002
#15	N/A	-16.79% Jun 5, 2001 - Aug 27, 2001