KLRS vs OPRX

Comparison between Kalaris Therapeutics Inc (KLRS, Company) and OptimizeRx Corp (OPRX, Company).

Both KLRS and OPRX are from the Healthcare sector.

5-Year PerformanceOPRX has outperformed KLRS, delivering a return of -36.4% compared to -61.4%

KLRS vs OPRX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	KLRS(COMPANY)	OPRX(COMPANY)
Market Cap	$96M	$95M
Max Drawdown	99.79%	99.32%
Sharpe Ratio	0.81	-1.03
5Y Beta	0.86	1.56
Industry	Biotechnology	Health Information Services
P/E Ratio	-1.93	13.89
Forward P/E	N/A	5.56
PEG Ratio	N/A	1.61
5Y EPS CAGR	-39.47%	N/A
Debt to Equity	0.00%	18.01%
Free Cash Flow Yield	-44.65%	15.03%
P/S Ratio	N/A	0.89
P/B Ratio	1.44	0.74

Market Cap

Winner

KLRS

$96M

OPRX

$95M

Max Drawdown

KLRS

99.79%

Winner

OPRX

99.32%

Sharpe Ratio

Winner

KLRS

0.81

OPRX

-1.03

5Y Beta

Winner

KLRS

0.86

OPRX

1.56

Industry

KLRS

Biotechnology

OPRX

Health Information Services

P/E Ratio

Winner

KLRS

-1.93

OPRX

13.89

Forward P/E

KLRS

N/A

OPRX

5.56

PEG Ratio

KLRS

N/A

OPRX

1.61

5Y EPS CAGR

KLRS

-39.47%

OPRX

N/A

Debt to Equity

Winner

KLRS

0.00%

OPRX

18.01%

Free Cash Flow Yield

KLRS

-44.65%

Winner

OPRX

15.03%

P/S Ratio

KLRS

N/A

OPRX

0.89

P/B Ratio

KLRS

1.44

Winner

OPRX

0.74

KLRS vs OPRX - Historical Returns

Returns include dividend reinvestment.

Period	KLRS	OPRX
1 month	-9.60%	-17.51%
3 months	-52.78%	-11.80%
6 months	-51.18%	-60.85%
1 year	+56.88%	-65.25%
5 years(CAGR)	-61.41%	-36.40%
10 years(CAGR)	N/A	+17.42%
Max(CAGR)	-56.65%	+14.26%

Winner

KLRS

-9.60%

OPRX

-17.51%

KLRS

-52.78%

Winner

OPRX

-11.80%

Winner

KLRS

-51.18%

OPRX

-60.85%

Winner

KLRS

+56.88%

OPRX

-65.25%

5Y(CAGR)

KLRS

-61.41%

Winner

OPRX

-36.40%

10Y(CAGR)

KLRS

N/A

OPRX

+17.42%

Max(CAGR)

KLRS

-56.65%

Winner

OPRX

+14.26%

KLRS vs OPRX - Annual Returns (2007 - 2026)

Returns include dividend reinvestment.

Year	KLRS	OPRX
2026	-47.83%	-57.89%
2025	-18.45%	+135.32%
2024	-38.98%	-65.38%
2023	-87.00%	-16.41%
2022	-62.06%	-73.30%
2021	-67.36%	+86.18%
2020	+51.40%	+212.54%
2019	N/A	-14.70%
2018	N/A	+612.34%
2017	N/A	+93.83%
2016	N/A	-34.68%
2015	N/A	+9.90%
2014	N/A	-30.06%
2013	N/A	+66.67%
2012	N/A	+19.10%
2011	N/A	-11.00%
2010	N/A	-63.56%
2009	N/A	-54.83%
2008	N/A	+82700.00%
2007	N/A	-98.81%

KLRS vs OPRX Drawdown Comparison

The maximum drawdown for KLRS was -99.79%, occurring on Aug 14, 2025. This drawdown has not yet recovered.

The maximum drawdown for OPRX was -99.32%, occurring on Nov 29, 2007. Recovery took 196 trading sessions.

The current KLRS drawdown is -99.60%. The current OPRX drawdown is -94.66%.

Rank	KLRS	OPRX
#1	-99.79% Dec 4, 2020 - Aug 14, 2025	-99.32% Jul 16, 2007 - Apr 28, 2008
#2	-50.70% Aug 11, 2020 - Dec 3, 2020	-96.10% Oct 21, 2021 - Nov 15, 2024
#3	-1.93% Jul 30, 2020 - Aug 3, 2020	-95.40% Feb 13, 2009 - Jun 11, 2018
#4	N/A	-62.83% Sep 27, 2018 - Aug 24, 2020
#5	N/A	-32.49% Feb 19, 2021 - Jun 25, 2021
#6	N/A	-29.76% Sep 18, 2008 - Nov 11, 2008
#7	N/A	-19.58% Jun 25, 2021 - Aug 5, 2021
#8	N/A	-14.47% Aug 5, 2021 - Sep 2, 2021
#9	N/A	-13.71% Nov 13, 2020 - Nov 25, 2020
#10	N/A	-12.82% Oct 7, 2020 - Oct 15, 2020
#11	N/A	-10.12% Aug 31, 2020 - Sep 15, 2020
#12	N/A	-9.71% Oct 15, 2020 - Nov 10, 2020
#13	N/A	-8.57% Jun 11, 2018 - Jun 18, 2018
#14	N/A	-8.57% Sep 3, 2021 - Sep 17, 2021
#15	N/A	-7.84% Sep 20, 2018 - Sep 27, 2018