JANX vs LXRX

Comparison between Janux Therapeutics Inc (JANX, Company) and Lexicon Pharmaceuticals Inc (LXRX, Company).

Both JANX and LXRX are from the Healthcare sector.

5-Year PerformanceJANX has outperformed LXRX, delivering a return of -11.6% compared to -17.0%

JANX vs LXRX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	JANX(COMPANY)	LXRX(COMPANY)
Market Cap	$800M	$800M
Max Drawdown	83.14%	99.91%
Sharpe Ratio	-0.45	1.54
5Y Beta	1.25	1.15
Industry	Biotechnology	Biotechnology
P/E Ratio	-6.90	-26.53
PEG Ratio	-0.19	-0.14
Debt to Equity	0.00%	24.49%
Free Cash Flow Yield	-9.81%	-4.85%
P/S Ratio	58.53	11.99
P/B Ratio	0.85	4.12

Market Cap

Winner

JANX

$800M

LXRX

$800M

Max Drawdown

Winner

JANX

83.14%

LXRX

99.91%

Sharpe Ratio

JANX

-0.45

Winner

LXRX

1.54

5Y Beta

JANX

1.25

Winner

LXRX

1.15

Industry

JANX

Biotechnology

LXRX

Biotechnology

P/E Ratio

JANX

-6.90

Winner

LXRX

-26.53

PEG Ratio

Winner

JANX

-0.19

LXRX

-0.14

Debt to Equity

Winner

JANX

0.00%

LXRX

24.49%

Free Cash Flow Yield

JANX

-9.81%

Winner

LXRX

-4.85%

P/S Ratio

JANX

58.53

Winner

LXRX

11.99

P/B Ratio

Winner

JANX

0.85

LXRX

4.12

JANX vs LXRX - Historical Returns

Returns include dividend reinvestment.

Period	JANX	LXRX
1 month	-5.90%	-20.33%
3 months	-2.76%	+11.63%
6 months	-11.37%	+47.69%
1 year	-46.95%	+175.94%
5 years(CAGR)	-11.62%	-16.98%
10 years(CAGR)	N/A	-18.40%
Max(CAGR)	-11.62%	-14.90%

Winner

JANX

-5.90%

LXRX

-20.33%

JANX

-2.76%

Winner

LXRX

+11.63%

JANX

-11.37%

Winner

LXRX

+47.69%

JANX

-46.95%

Winner

LXRX

+175.94%

5Y(CAGR)

Winner

JANX

-11.62%

LXRX

-16.98%

10Y(CAGR)

JANX

N/A

LXRX

-18.40%

Max(CAGR)

Winner

JANX

-11.62%

LXRX

-14.90%

JANX vs LXRX - Annual Returns (2000 - 2026)

Returns include dividend reinvestment.

Year	JANX	LXRX
2026	-0.66%	+68.42%
2025	-74.08%	+47.99%
2024	+385.84%	-53.55%
2023	-23.47%	-23.12%
2022	-34.93%	-50.90%
2021	-21.55%	+11.93%
2020	N/A	-16.38%
2019	N/A	-39.94%
2018	N/A	-34.39%
2017	N/A	-30.42%
2016	N/A	+5.17%
2015	N/A	+105.98%
2014	N/A	-49.17%
2013	N/A	-24.41%
2012	N/A	+76.80%
2011	N/A	-14.00%
2010	N/A	-16.76%
2009	N/A	+18.06%
2008	N/A	-54.10%
2007	N/A	-17.89%
2006	N/A	-5.25%
2005	N/A	-50.68%
2004	N/A	+28.18%
2003	N/A	+14.37%
2002	N/A	-57.69%
2001	N/A	-17.57%
2000	N/A	-11.31%

JANX vs LXRX Drawdown Comparison

The maximum drawdown for JANX was -83.14%, occurring on Nov 9, 2023. Recovery took 643 trading sessions.

The maximum drawdown for LXRX was -99.91%, occurring on Mar 3, 2025. This drawdown has not yet recovered.

The current JANX drawdown is -79.71%. The current LXRX drawdown is -99.42%.

Rank	JANX	LXRX
#1	-83.14% Aug 5, 2021 - Feb 27, 2024	-99.91% Jul 21, 2000 - Mar 3, 2025
#2	-81.78% Dec 4, 2024 - Feb 5, 2026	-51.33% Apr 7, 2000 - Jun 20, 2000
#3	-45.52% May 3, 2024 - Dec 4, 2024	-15.33% Jul 10, 2000 - Jul 20, 2000
#4	-29.41% Feb 27, 2024 - Apr 11, 2024	-8.08% Jun 21, 2000 - Jun 23, 2000
#5	-26.12% Jun 11, 2021 - Jun 29, 2021	-5.17% Jun 28, 2000 - Jul 5, 2000
#6	-10.54% Apr 12, 2024 - Apr 29, 2024	N/A
#7	-9.54% Jul 23, 2021 - Jul 29, 2021	N/A
#8	-4.25% Jul 9, 2021 - Jul 20, 2021	N/A
#9	-3.03% Aug 2, 2021 - Aug 5, 2021	N/A
#10	-1.66% Jun 29, 2021 - Jul 2, 2021	N/A
#11	-1.65% Jul 7, 2021 - Jul 9, 2021	N/A