IOVA vs VERX

Comparison between Iovance Biotherapeutics Inc (IOVA, Company) and Vertex Inc Class A (VERX, Company).

IOVA is from the Healthcare sector, while VERX is from the Technology sector.

5-Year PerformanceVERX has outperformed IOVA, delivering a return of -9.5% compared to -23.4%

IOVA vs VERX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	IOVA(COMPANY)	VERX(COMPANY)
Market Cap	$1.90B	$1.90B
Max Drawdown	99.37%	82.05%
Sharpe Ratio	1.24	-1.41
5Y Beta	1.60	0.69
Industry	Biotechnology	Software - Application
P/E Ratio	-4.73	442.99
Forward P/E	N/A	15.02
PEG Ratio	0.00	N/A
5Y EPS CAGR	-12.60%	N/A
Debt to Equity	0.00%	145.13%
Free Cash Flow Yield	-16.04%	3.07%
P/S Ratio	6.82	2.43
P/B Ratio	2.52	8.47

Market Cap

IOVA

$1.90B

Winner

VERX

$1.90B

Max Drawdown

IOVA

99.37%

Winner

VERX

82.05%

Sharpe Ratio

Winner

IOVA

1.24

VERX

-1.41

5Y Beta

IOVA

1.60

Winner

VERX

0.69

Industry

IOVA

Biotechnology

VERX

Software - Application

P/E Ratio

Winner

IOVA

-4.73

VERX

442.99

Forward P/E

IOVA

N/A

VERX

15.02

PEG Ratio

IOVA

0.00

VERX

N/A

5Y EPS CAGR

IOVA

-12.60%

VERX

N/A

Debt to Equity

Winner

IOVA

0.00%

VERX

145.13%

Free Cash Flow Yield

IOVA

-16.04%

Winner

VERX

3.07%

P/S Ratio

IOVA

6.82

Winner

VERX

2.43

P/B Ratio

Winner

IOVA

2.52

VERX

8.47

IOVA vs VERX - Historical Returns

Returns include dividend reinvestment.

Period	IOVA	VERX
1 month	+48.21%	-9.96%
3 months	+51.83%	-8.61%
6 months	+145.45%	-26.45%
1 year	+140.70%	-57.31%
5 years(CAGR)	-23.40%	-9.52%
10 years(CAGR)	-3.84%	N/A
Max(CAGR)	-16.63%	-11.37%

Winner

IOVA

+48.21%

VERX

-9.96%

Winner

IOVA

+51.83%

VERX

-8.61%

Winner

IOVA

+145.45%

VERX

-26.45%

Winner

IOVA

+140.70%

VERX

-57.31%

5Y(CAGR)

IOVA

-23.40%

Winner

VERX

-9.52%

10Y(CAGR)

IOVA

-3.84%

VERX

N/A

Max(CAGR)

IOVA

-16.63%

Winner

VERX

-11.37%

IOVA vs VERX - Annual Returns (2010 - 2026)

Returns include dividend reinvestment.

Year	IOVA	VERX
2026	+146.43%	-39.14%
2025	-64.96%	-62.46%
2024	-8.64%	+99.07%
2023	+33.06%	+84.39%
2022	-66.54%	-13.58%
2021	-58.73%	-53.13%
2020	+73.91%	+45.63%
2019	+192.91%	N/A
2018	+9.26%	N/A
2017	+10.34%	N/A
2016	-5.44%	N/A
2015	-4.10%	N/A
2014	-19.28%	N/A
2013	-47.50%	N/A
2012	-78.00%	N/A
2011	-20.00%	N/A
2010	+13.64%	N/A

IOVA vs VERX Drawdown Comparison

The maximum drawdown for IOVA was -99.37%, occurring on Apr 12, 2013. This drawdown has not yet recovered.

The maximum drawdown for VERX was -82.05%, occurring on Jun 22, 2026. This drawdown has not yet recovered.

The current IOVA drawdown is -96.09%. The current VERX drawdown is -80.37%.

Rank	IOVA	VERX
#1	-99.37% Jun 7, 2011 - Apr 12, 2013	-82.05% Jan 28, 2025 - Jun 22, 2026
#2	-13.51% Nov 15, 2010 - Dec 1, 2010	-75.40% Feb 19, 2021 - Jul 23, 2024
#3	-12.70% Feb 9, 2011 - Apr 29, 2011	-25.40% Aug 27, 2020 - Dec 17, 2020
#4	-9.09% Oct 15, 2010 - Nov 15, 2010	-17.32% Dec 23, 2020 - Feb 12, 2021
#5	-7.56% Dec 1, 2010 - Dec 14, 2010	-13.47% Jul 23, 2024 - Oct 2, 2024
#6	-6.99% May 25, 2011 - Jun 2, 2011	-9.84% Dec 3, 2024 - Jan 21, 2025
#7	-6.30% Apr 29, 2011 - May 17, 2011	-8.19% Aug 6, 2020 - Aug 20, 2020
#8	-2.22% May 18, 2011 - May 20, 2011	-5.56% Nov 8, 2024 - Nov 20, 2024
#9	N/A	-4.69% Oct 3, 2024 - Oct 16, 2024
#10	N/A	-3.26% Oct 21, 2024 - Nov 5, 2024
#11	N/A	-2.89% Jul 30, 2020 - Aug 4, 2020
#12	N/A	-2.58% Feb 12, 2021 - Feb 18, 2021
#13	N/A	-1.63% Nov 26, 2024 - Dec 3, 2024
#14	N/A	-1.20% Aug 24, 2020 - Aug 26, 2020
#15	N/A	-0.65% Jan 21, 2025 - Jan 24, 2025