ICLR vs CYTK

Comparison between Icon Plc (ICLR, Company) and Cytokinetics Inc (CYTK, Company).

Both ICLR and CYTK are from the Healthcare sector.

5-Year PerformanceCYTK has outperformed ICLR, delivering a return of +24.8% compared to -12.6%

ICLR vs CYTK - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	ICLR(COMPANY)	CYTK(COMPANY)
Market Cap	$9.48B	$9.52B
Max Drawdown	76.87%	97.09%
Sharpe Ratio	0.06	1.77
5Y Beta	1.06	0.80
Industry	Diagnostics & Research	Biotechnology
P/E Ratio	11.98	-11.28
Forward P/E	10.33	117.65
PEG Ratio	0.37	-0.39
5Y EPS CAGR	22.96%	27.73%
Debt to Equity	35.67%	-126.00%
Free Cash Flow Yield	11.80%	-5.77%
P/S Ratio	1.13	99.08
P/B Ratio	1.02	60.31

Market Cap

ICLR

$9.48B

Winner

CYTK

$9.52B

Max Drawdown

Winner

ICLR

76.87%

CYTK

97.09%

Sharpe Ratio

ICLR

0.06

Winner

CYTK

1.77

5Y Beta

ICLR

1.06

Winner

CYTK

0.80

Industry

ICLR

Diagnostics & Research

CYTK

Biotechnology

P/E Ratio

ICLR

11.98

Winner

CYTK

-11.28

Forward P/E

Winner

ICLR

10.33

CYTK

117.65

PEG Ratio

ICLR

0.37

Winner

CYTK

-0.39

5Y EPS CAGR

ICLR

22.96%

Winner

CYTK

27.73%

Debt to Equity

ICLR

35.67%

Winner

CYTK

-126.00%

Free Cash Flow Yield

Winner

ICLR

11.80%

CYTK

-5.77%

P/S Ratio

Winner

ICLR

1.13

CYTK

99.08

P/B Ratio

Winner

ICLR

1.02

CYTK

60.31

ICLR vs CYTK - Historical Returns

Returns include dividend reinvestment.

Period	ICLR	CYTK
1 month	+3.56%	+18.52%
3 months	+25.90%	+18.68%
6 months	-27.80%	+18.36%
1 year	-11.45%	+162.13%
5 years(CAGR)	-12.57%	+24.85%
10 years(CAGR)	+6.30%	+26.49%
Max(CAGR)	+14.30%	-0.93%

ICLR

+3.56%

Winner

CYTK

+18.52%

Winner

ICLR

+25.90%

CYTK

+18.68%

ICLR

-27.80%

Winner

CYTK

+18.36%

ICLR

-11.45%

Winner

CYTK

+162.13%

5Y(CAGR)

ICLR

-12.57%

Winner

CYTK

+24.85%

10Y(CAGR)

ICLR

+6.30%

Winner

CYTK

+26.49%

Max(CAGR)

Winner

ICLR

+14.30%

CYTK

-0.93%

ICLR vs CYTK - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	ICLR	CYTK
2026	-37.94%	+27.39%
2025	-14.30%	+29.86%
2024	-25.32%	-44.08%
2023	+46.22%	+88.25%
2022	-34.38%	-0.39%
2021	+61.29%	+133.03%
2020	+15.01%	+96.97%
2019	+34.83%	+55.57%
2018	+12.87%	-27.77%
2017	+50.11%	-34.27%
2016	+0.82%	+21.50%
2015	+50.55%	+41.93%
2014	+27.60%	+19.20%
2013	+43.32%	+61.64%
2012	+60.74%	-32.65%
2011	-21.76%	-55.56%
2010	+1.34%	-32.80%
2009	+13.18%	+2.11%
2008	-36.40%	-37.36%
2007	+58.86%	-43.29%
2006	+83.68%	+19.30%
2005	+8.26%	-33.33%
2004	-11.32%	-36.34%
2003	+55.60%	N/A
2002	-5.74%	N/A
2001	+86.31%	N/A
2000	+0.76%	N/A
1999	+25.93%	N/A

ICLR vs CYTK Drawdown Comparison

The maximum drawdown for ICLR was -76.87%, occurring on Feb 12, 2026. This drawdown has not yet recovered.

The maximum drawdown for CYTK was -97.09%, occurring on Oct 10, 2014. Recovery took 4952 trading sessions.

The current ICLR drawdown is -66.18%. The current CYTK drawdown is -27.23%.

Rank	ICLR	CYTK
#1	-76.87% Jul 16, 2024 - Feb 12, 2026	-97.09% May 5, 2004 - Jan 8, 2024
#2	-67.73% Aug 11, 2008 - Feb 7, 2014	-72.39% Jan 8, 2024 - May 15, 2025
#3	-60.60% Jul 19, 2001 - Oct 1, 2003	-1.52% May 3, 2004 - May 5, 2004
#4	-43.85% Dec 31, 2021 - Feb 22, 2024	N/A
#5	-42.39% Feb 9, 2000 - Jan 29, 2001	N/A
#6	-34.57% Feb 19, 2020 - Jul 14, 2020	N/A
#7	-33.62% Jan 9, 2004 - Sep 28, 2005	N/A
#8	-32.60% Feb 13, 2001 - Jun 5, 2001	N/A
#9	-26.02% Sep 30, 2005 - Apr 20, 2006	N/A
#10	-24.35% Aug 10, 2015 - Oct 20, 2016	N/A
#11	-24.11% Nov 19, 1999 - Dec 29, 1999	N/A
#12	-22.96% Mar 19, 2014 - Jul 30, 2014	N/A
#13	-22.36% Sep 28, 2018 - Jun 28, 2019	N/A
#14	-22.22% Jan 20, 2021 - May 5, 2021	N/A
#15	-15.81% Feb 25, 2008 - Apr 29, 2008	N/A