IBRN vs ISHP
Comparison between ISHARES NEUROSCIENCE AND HEALTHCARE ETF (IBRN, ETF) and FIRST TRUST S-NETWORK E-COMMERCE ETF (ISHP, ETF).
IBRN vs ISHP - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Net Assets
IBRN
$5.20M
Winner
ISHP
$5.30M
Expense Ratio
Winner
IBRN
0.47%
ISHP
0.60%
Max Drawdown
Winner
IBRN
35.63%
ISHP
47.93%
Sharpe Ratio
Winner
IBRN
1.57
ISHP
-0.82
5Y Beta
IBRN
0.97
Winner
ISHP
0.96
P/E Ratio
Winner
IBRN
-14.78
ISHP
21.06
Forward P/E
IBRN
N/A
ISHP
13.77
PEG Ratio
IBRN
N/A
ISHP
0.24
5Y Dividends CAGR
IBRN
N/A
ISHP
26.34%
Debt to Equity
Winner
IBRN
22.09%
ISHP
55.45%
P/S Ratio
IBRN
6.61
Winner
ISHP
0.54
P/B Ratio
IBRN
4.02
Winner
ISHP
2.78
IBRN vs ISHP - Holdings Comparison
IBRN and ISHP have 1 common holdings. Overlap is -1.31%
IBRN's top 25 holdings weight is 77.87%. ISHP's top 25 holdings weight is 48.34%.
| Rank | IBRN | ISHP |
|---|---|---|
| #1 | XENON PHARMACEUTICALS INC (XENE) - 5.17% | FEDEX CORP (FDX) - 2.31% |
| #2 | PTC THERAPEUTICS INC (PTCT) - 4.21% | COSCO SHIPPING HOLDINGS CO LTD CLASS H (n/a) - 2.16% |
| #3 | BIOGEN INC (BIIB) - 3.96% | EBAY INC (EBAY) - 2.13% |
| #4 | NEUROCRINE BIOSCIENCES INC (NBIX) - 3.95% | WALMART INC (WMT) - 2.13% |
| #5 | ALKERMES PLC (ALKS) - 3.86% | PROLOGIS INC (PLD) - 2.07% |
| #6 | AXSOME THERAPEUTICS INC (AXSM) - 3.85% | JD.COM INC ADR (JD) - 2.03% |
| #7 | SCHOLAR ROCK HOLDING CORP (SRRK) - 3.84% | A P MOLLER MAERSK AS CLASS B (n/a) - 2.01% |
| #8 | ACADIA PHARMACEUTICALS INC (ACAD) - 3.78% | DEUTSCHE POST AG (n/a) - 1.98% |
| #9 | ARGENX SE ADR (ARGX) - 3.78% | TAIWAN MOBILE CO LTD (n/a) - 1.98% |
| #10 | ARROWHEAD PHARMACEUTICALS INC (ARWR) - 3.78% | META PLATFORMS INC CLASS A (META) - 1.97% |
| #11 | n/a (PRAX) - 3.77% | ALPHABET INC CLASS A (GOOGL) - 1.97% |
| #12 | DENALI THERAPEUTICS INC (DNLI) - 3.55% | AMAZON.COM INC (AMZN) - 1.95% |
| #13 | DIANTHUS THERAPEUTICS INC (DNTH) - 3.40% | n/a (n/a) - 1.95% |
| #14 | SUPERNUS PHARMACEUTICALS INC (SUPN) - 3.19% | WILLIAMS-SONOMA INC (WSM) - 1.89% |
| #15 | CATALYST PHARMACEUTICALS INC (CPRX) - 3.05% | LY CORP (n/a) - 1.88% |
| #16 | CENTESSA PHARMACEUTICALS PLC ADR (CNTA) - 2.91% | CORPAY INC (CPAY) - 1.86% |
| #17 | EDGEWISE THERAPEUTICS INC (EWTX) - 2.72% | AIRBNB INC ORDINARY SHARES CLASS A (ABNB) - 1.86% |
| #18 | DYNE THERAPEUTICS INC ORDINARY SHARES (DYN) - 2.69% | UNITED PARCEL SERVICE INC CLASS B (UPS) - 1.86% |
| #19 | SAREPTA THERAPEUTICS INC (SRPT) - 2.10% | NEXT PLC (n/a) - 1.84% |
| #20 | n/a (n/a) - 2.01% | KE HOLDINGS INC ADR (BEKE) - 1.83% |
| #21 | AXOGEN INC (AXGN) - 1.92% | REA GROUP LTD (n/a) - 1.82% |
| #22 | H. LUNDBECK AS ORDINARY SHARES CLASS B (n/a) - 1.85% | COUPANG INC ORDINARY SHARES CLASS A (CPNG) - 1.78% |
| #23 | CAPRICOR THERAPEUTICS INC (CAPR) - 1.75% | ALLEGRO.EU SA ORDINARY SHARES (n/a) - 1.74% |
| #24 | BIOARCTIC AB CLASS B (n/a) - 1.46% | GLOBAL PAYMENTS INC (GPN) - 1.68% |
| #25 | BIOHAVEN LTD (BHVN) - 1.32% | BEST BUY CO INC (BBY) - 1.66% |
| Total Holdings | 101 | 65 |
IBRN vs ISHP - Historical Returns
Returns include dividend reinvestment.
1M
IBRN
-3.52%
Winner
ISHP
-3.34%
3M
Winner
IBRN
+10.71%
ISHP
-3.76%
6M
Winner
IBRN
+5.65%
ISHP
-13.90%
1Y
Winner
IBRN
+48.96%
ISHP
-11.68%
5Y(CAGR)
IBRN
N/A
ISHP
+0.95%
10Y(CAGR)
IBRN
N/A
ISHP
+6.78%
Max(CAGR)
Winner
IBRN
+9.53%
ISHP
+6.78%
IBRN vs ISHP - Annual Returns (2016 - 2026)
Returns include dividend reinvestment.
| Year | IBRN | ISHP |
|---|---|---|
| 2026 | +7.44% | -14.35% |
| 2025 | +26.05% | +12.26% |
| 2024 | -1.58% | +26.80% |
| 2023 | +2.83% | +26.73% |
| 2022 | +5.85% | -33.60% |
| 2021 | N/A | +29.95% |
| 2020 | N/A | +15.53% |
| 2019 | N/A | +19.66% |
| 2018 | N/A | -3.09% |
| 2017 | N/A | +7.66% |
| 2016 | N/A | +2.16% |
IBRN vs ISHP Drawdown Comparison
The maximum drawdown for IBRN was -35.38%, occurring on Apr 8, 2025. Recovery took 232 trading sessions.
The maximum drawdown for ISHP was -47.58%, occurring on Nov 3, 2022. Recovery took 764 trading sessions.
The current IBRN drawdown is -5.34%. The current ISHP drawdown is -20.76%.
| Rank | IBRN | ISHP |
|---|---|---|
| #1 | -35.38% Nov 11, 2024 - Oct 16, 2025 | -47.58% Nov 22, 2021 - Dec 6, 2024 |
| #2 | -30.32% Feb 2, 2023 - Oct 17, 2024 | -33.11% Feb 19, 2020 - Jul 21, 2020 |
| #3 | -9.30% Sep 12, 2022 - Oct 4, 2022 | -24.74% Sep 18, 2025 - Mar 27, 2026 |
| #4 | -8.80% Jan 22, 2026 - Apr 8, 2026 | -21.02% Sep 12, 2018 - Nov 26, 2019 |
| #5 | -8.01% Oct 28, 2025 - Nov 24, 2025 | -20.94% Feb 19, 2025 - Jul 1, 2025 |
| #6 | -7.97% Dec 2, 2022 - Feb 2, 2023 | -14.35% Jan 29, 2018 - Aug 17, 2018 |
| #7 | -6.80% Oct 4, 2022 - Nov 10, 2022 | -12.15% Dec 9, 2016 - Dec 5, 2017 |
| #8 | -6.45% May 6, 2026 - May 19, 2026 | -10.29% Feb 12, 2021 - Apr 5, 2021 |
| #9 | -5.12% Apr 17, 2026 - May 6, 2026 | -8.67% Dec 9, 2024 - Feb 6, 2025 |
| #10 | -4.58% Nov 28, 2025 - Dec 4, 2025 | -8.44% Oct 15, 2020 - Nov 23, 2020 |
| #11 | -4.11% Aug 26, 2022 - Sep 8, 2022 | -7.46% Jun 8, 2021 - Aug 23, 2021 |
| #12 | -4.07% Dec 8, 2025 - Jan 21, 2026 | -6.91% Aug 25, 2021 - Oct 25, 2021 |
| #13 | -3.16% Oct 18, 2024 - Nov 6, 2024 | -6.08% Sep 2, 2020 - Oct 5, 2020 |
| #14 | -2.90% Nov 15, 2022 - Nov 25, 2022 | -4.87% May 7, 2021 - May 17, 2021 |
| #15 | -2.09% Nov 25, 2022 - Nov 30, 2022 | -4.84% Dec 19, 2019 - Feb 19, 2020 |
Correlation
Correlation between IBRN and ISHP is 0.39 which considered as a weak positive correlation - the stocks show a slight tendency to move together.
0.39
-101
Dividend Comparison (2016 - 2025)
IBRN vs ISHP dividend yield comparison.
| Year | IBRN | ISHP |
|---|---|---|
| 2025 | 0.99% | 1.34% |
| 2024 | 0.40% | 1.02% |
| 2023 | 0.06% | 1.58% |
| 2022 | 0.00% | 0.76% |
| 2021 | 0.00% | 0.53% |
| 2020 | 0.00% | 0.82% |
| 2019 | 0.00% | 1.16% |
| 2018 | 0.00% | 0.89% |
| 2017 | 0.00% | 1.65% |
| 2016 | 0.00% | 0.23% |
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