HBIO vs BRNS

Comparison between Harvard Bioscience Inc (HBIO, Company) and Barinthus Biotherapeutics Plc. (BRNS, Company).

Both HBIO and BRNS are from the Healthcare sector.

5-Year PerformanceHBIO has outperformed BRNS, delivering a return of -39.4% compared to -45.9%

HBIO vs BRNS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	HBIO(COMPANY)	BRNS(COMPANY)
Market Cap	$26M	$27M
Max Drawdown	98.00%	96.82%
Sharpe Ratio	0.61	0.11
5Y Beta	2.15	0.68
Industry	Medical Instruments & Supplies	Biotechnology
P/E Ratio	-2.69	-0.51
Forward P/E	15.06	N/A
5Y EPS CAGR	16.59%	N/A
Debt to Equity	360.45%	0.00%
Free Cash Flow Yield	7.21%	N/A

Market Cap

HBIO

$26M

Winner

BRNS

$27M

Max Drawdown

HBIO

98.00%

Winner

BRNS

96.82%

Sharpe Ratio

Winner

HBIO

0.61

BRNS

0.11

5Y Beta

HBIO

2.15

Winner

BRNS

0.68

Industry

HBIO

Medical Instruments & Supplies

BRNS

Biotechnology

P/E Ratio

Winner

HBIO

-2.69

BRNS

-0.51

Forward P/E

HBIO

15.06

BRNS

N/A

5Y EPS CAGR

HBIO

16.59%

BRNS

N/A

Debt to Equity

HBIO

360.45%

Winner

BRNS

0.00%

Free Cash Flow Yield

HBIO

7.21%

BRNS

N/A

HBIO vs BRNS - Historical Returns

Returns include dividend reinvestment.

Period	HBIO	BRNS
1 month	+17.40%	+3.71%
3 months	+20.29%	+3.65%
6 months	-23.49%	-9.46%
1 year	+20.34%	-23.89%
5 years(CAGR)	-39.38%	-45.91%
10 years(CAGR)	-16.11%	N/A
Max(CAGR)	-8.43%	-44.89%

Winner

HBIO

+17.40%

BRNS

+3.71%

Winner

HBIO

+20.29%

BRNS

+3.65%

HBIO

-23.49%

Winner

BRNS

-9.46%

Winner

HBIO

+20.34%

BRNS

-23.89%

5Y(CAGR)

Winner

HBIO

-39.38%

BRNS

-45.91%

10Y(CAGR)

HBIO

-16.11%

BRNS

N/A

Max(CAGR)

Winner

HBIO

-8.43%

BRNS

-44.89%

HBIO vs BRNS - Annual Returns (2001 - 2026)

Returns include dividend reinvestment.

Year	HBIO	BRNS
2026	-9.96%	-9.90%
2025	-67.05%	-43.54%
2024	-60.85%	-67.35%
2023	+99.63%	+53.75%
2022	-61.20%	-78.87%
2021	+67.06%	-21.21%
2020	+40.66%	N/A
2019	-4.69%	N/A
2018	-3.64%	N/A
2017	+13.79%	N/A
2016	-5.57%	N/A
2015	-36.79%	N/A
2014	+19.37%	N/A
2013	+35.98%	N/A
2012	+10.61%	N/A
2011	-5.15%	N/A
2010	+11.48%	N/A
2009	+35.74%	N/A
2008	-40.72%	N/A
2007	-9.66%	N/A
2006	+8.46%	N/A
2005	-1.11%	N/A
2004	-47.51%	N/A
2003	+173.85%	N/A
2002	-66.52%	N/A
2001	+42.00%	N/A

HBIO vs BRNS Drawdown Comparison

The maximum drawdown for HBIO was -97.42%, occurring on May 28, 2025. This drawdown has not yet recovered.

The maximum drawdown for BRNS was -96.82%, occurring on Apr 1, 2026. This drawdown has not yet recovered.

The current HBIO drawdown is -94.67%. The current BRNS drawdown is -96.10%.

Rank	HBIO	BRNS
#1	-97.42% Aug 31, 2001 - May 28, 2025	-96.82% May 17, 2021 - Apr 1, 2026
#2	-27.93% May 21, 2001 - Aug 20, 2001	-8.56% May 3, 2021 - May 12, 2021
#3	-17.19% Mar 21, 2001 - Apr 19, 2001	N/A
#4	-6.74% Apr 20, 2001 - Apr 26, 2001	N/A
#5	-5.21% May 11, 2001 - May 18, 2001	N/A
#6	-2.74% Aug 20, 2001 - Aug 23, 2001	N/A
#7	-2.50% May 1, 2001 - May 4, 2001	N/A
#8	-2.08% Aug 27, 2001 - Aug 31, 2001	N/A
#9	-1.29% Apr 26, 2001 - May 1, 2001	N/A
#10	-1.23% May 4, 2001 - May 11, 2001	N/A