GLSI vs AVTX

Comparison between Greenwich LifeSciences Inc (GLSI, Company) and Avalo Therapeutics Inc (AVTX, Company).

Both GLSI and AVTX are from the Healthcare sector.

5-Year PerformanceGLSI has outperformed AVTX, delivering a return of -10.6% compared to -72.5%

GLSI vs AVTX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	GLSI(COMPANY)	AVTX(COMPANY)
Market Cap	$403M	$404M
Max Drawdown	90.11%	99.98%
Sharpe Ratio	1.35	1.61
5Y Beta	1.47	0.54
Industry	Biotechnology	Biotechnology
P/E Ratio	-20.05	-3.90
PEG Ratio	-0.25	N/A
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-2.13%	-12.74%
P/S Ratio	N/A	9875.25
P/B Ratio	183.82	3.78

Market Cap

GLSI

$403M

Winner

AVTX

$404M

Max Drawdown

Winner

GLSI

90.11%

AVTX

99.98%

Sharpe Ratio

GLSI

1.35

Winner

AVTX

1.61

5Y Beta

GLSI

1.47

Winner

AVTX

0.54

Industry

GLSI

Biotechnology

AVTX

Biotechnology

P/E Ratio

Winner

GLSI

-20.05

AVTX

-3.90

PEG Ratio

GLSI

-0.25

AVTX

N/A

Debt to Equity

GLSI

0.00%

AVTX

0.00%

Free Cash Flow Yield

Winner

GLSI

-2.13%

AVTX

-12.74%

P/S Ratio

GLSI

N/A

AVTX

9875.25

P/B Ratio

GLSI

183.82

Winner

AVTX

3.78

GLSI vs AVTX - Historical Returns

Returns include dividend reinvestment.

Period	GLSI	AVTX
1 month	-0.22%	-19.43%
3 months	-9.81%	-25.48%
6 months	+148.88%	-25.40%
1 year	+135.95%	+202.54%
5 years(CAGR)	-10.64%	-72.50%
10 years(CAGR)	N/A	-45.44%
Max(CAGR)	+29.99%	-47.38%

Winner

GLSI

-0.22%

AVTX

-19.43%

Winner

GLSI

-9.81%

AVTX

-25.48%

Winner

GLSI

+148.88%

AVTX

-25.40%

GLSI

+135.95%

Winner

AVTX

+202.54%

5Y(CAGR)

Winner

GLSI

-10.64%

AVTX

-72.50%

10Y(CAGR)

GLSI

N/A

AVTX

-45.44%

Max(CAGR)

Winner

GLSI

+29.99%

AVTX

-47.38%

GLSI vs AVTX - Annual Returns (2015 - 2026)

Returns include dividend reinvestment.

Year	GLSI	AVTX
2026	+14.28%	-23.03%
2025	+78.96%	+115.42%
2024	+3.98%	-14.70%
2023	-27.90%	-99.24%
2022	-35.59%	-76.80%
2021	-30.35%	-35.61%
2020	+629.40%	-47.51%
2019	N/A	+54.44%
2018	N/A	-3.00%
2017	N/A	+259.51%
2016	N/A	-77.13%
2015	N/A	-16.25%

GLSI vs AVTX Drawdown Comparison

The maximum drawdown for GLSI was -90.11%, occurring on Jun 16, 2022. This drawdown has not yet recovered.

The maximum drawdown for AVTX was -99.98%, occurring on May 28, 2025. This drawdown has not yet recovered.

The current GLSI drawdown is -69.19%. The current AVTX drawdown is -99.94%.

Rank	GLSI	AVTX
#1	-90.11% Dec 10, 2020 - Jun 16, 2022	-99.98% Feb 27, 2019 - May 28, 2025
#2	-30.50% Sep 25, 2020 - Nov 19, 2020	-91.55% Nov 23, 2016 - Mar 7, 2018
#3	-7.50% Dec 4, 2020 - Dec 9, 2020	-60.57% Mar 17, 2016 - Nov 18, 2016
#4	-3.83% Nov 23, 2020 - Dec 2, 2020	-46.64% Mar 7, 2018 - Feb 25, 2019
#5	-1.48% Nov 19, 2020 - Nov 23, 2020	-35.56% Nov 16, 2015 - Mar 16, 2016