FMED vs NXTI
Comparison between FIDELITY DISRUPTIVE MEDICINE ETF (FMED, ETF) and SIMPLIFY NEXT INTANGIBLE CORE INDEX ETF (NXTI, ETF).
FMED vs NXTI - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Net Assets
Winner
FMED
$41M
NXTI
$41M
Expense Ratio
FMED
0.50%
Winner
NXTI
0.25%
Max Drawdown
FMED
21.84%
Winner
NXTI
20.46%
Sharpe Ratio
FMED
0.03
Winner
NXTI
0.73
5Y Beta
Winner
FMED
0.79
NXTI
0.95
P/E Ratio
Winner
FMED
-35.26
NXTI
26.34
Forward P/E
FMED
21.86
Winner
NXTI
20.51
5Y EPS CAGR
FMED
6.65%
Winner
NXTI
12.67%
Debt to Equity
Winner
FMED
14.39%
NXTI
65.82%
P/S Ratio
FMED
4.72
Winner
NXTI
2.62
P/B Ratio
Winner
FMED
4.48
NXTI
5.07
FMED vs NXTI - Holdings Comparison
FMED and NXTI have 8 common holdings. Overlap is 1.39%
FMED's top 25 holdings weight is 72.01%. NXTI's top 25 holdings weight is 57.66%.
| Rank | FMED | NXTI |
|---|---|---|
| #1 | n/a (n/a) - 12.74% | CISCO SYSTEMS INC (CSCO) - 6.13% |
| #2 | n/a (LFST) - 4.42% | n/a (PLTR) - 4.29% |
| #3 | UCB SA (n/a) - 4.35% | WALMART INC (WMT) - 3.88% |
| #4 | n/a (TXG) - 3.47% | INTERNATIONAL BUSINESS MACHINES CORP (IBM) - 3.80% |
| #5 | DANAHER CORP (DHR) - 3.39% | JOHNSON & JOHNSON (JNJ) - 3.39% |
| #6 | LEGEND BIOTECH CORP ADR (LEGN) - 3.15% | QUALCOMM INC (QCOM) - 3.24% |
| #7 | INTUITIVE SURGICAL INC (ISRG) - 2.84% | n/a (DELL) - 3.23% |
| #8 | ARGENX SE ADR (ARGX) - 2.75% | BERKSHIRE HATHAWAY INC CLASS B (BRK-B) - 2.98% |
| #9 | COGENT BIOSCIENCES INC (COGT) - 2.75% | PALO ALTO NETWORKS INC (PANW) - 2.84% |
| #10 | ALNYLAM PHARMACEUTICALS INC (ALNY) - 2.72% | SEAGATE TECHNOLOGY HOLDINGS PLC (STX) - 2.20% |
| #11 | THERMO FISHER SCIENTIFIC INC (TMO) - 2.42% | WESTERN DIGITAL CORP (WDC) - 2.08% |
| #12 | UNITEDHEALTH GROUP INC (UNH) - 2.30% | MERCK & CO INC (MRK) - 1.82% |
| #13 | BIO-TECHNE CORP (TECH) - 2.22% | MASTERCARD INC CLASS A (MA) - 1.76% |
| #14 | EDWARDS LIFESCIENCES CORP (EW) - 2.20% | EXXON MOBIL CORP (XOM) - 1.76% |
| #15 | ASCENDIS PHARMA AS (ASND) - 2.10% | SERVICENOW INC (NOW) - 1.67% |
| #16 | MODERNA INC (MRNA) - 2.09% | ADOBE INC (ADBE) - 1.43% |
| #17 | CARIS LIFE SCIENCES INC (CAI) - 1.91% | CADENCE DESIGN SYSTEMS INC (CDNS) - 1.39% |
| #18 | XENON PHARMACEUTICALS INC (XENE) - 1.88% | FORTINET INC (FTNT) - 1.32% |
| #19 | SARTORIUS STEDIM BIOTECH SA (n/a) - 1.87% | SPOTIFY TECHNOLOGY SA (SPOT) - 1.30% |
| #20 | HEARTFLOW INC (HTFL) - 1.85% | GE AEROSPACE (GE) - 1.28% |
| #21 | KYMERA THERAPEUTICS INC ORDINARY SHARES (KYMR) - 1.79% | CATERPILLAR INC (CAT) - 1.26% |
| #22 | INSMED INC (INSM) - 1.79% | LAM RESEARCH CORP (LRCX) - 1.23% |
| #23 | REVOLUTION MEDICINES INC ORDINARY SHARES (RVMD) - 1.71% | APPLIED MATERIALS INC (AMAT) - 1.15% |
| #24 | VAXCYTE INC ORDINARY SHARES (PCVX) - 1.67% | COMCAST CORP CLASS A (CMCSA) - 1.12% |
| #25 | VERACYTE INC (VCYT) - 1.63% | DATADOG INC CLASS A (DDOG) - 1.11% |
| Total Holdings | 73 | 201 |
FMED vs NXTI - Historical Returns
Returns include dividend reinvestment.
1M
FMED
-1.41%
Winner
NXTI
+5.97%
3M
FMED
-4.47%
Winner
NXTI
+11.00%
6M
FMED
-13.97%
Winner
NXTI
+4.33%
1Y
FMED
+1.52%
Winner
NXTI
+13.46%
Max(CAGR)
FMED
-1.05%
Winner
NXTI
+18.16%
FMED vs NXTI - Annual Returns (2023 - 2026)
Returns include dividend reinvestment.
| Year | FMED | NXTI |
|---|---|---|
| 2026 | -9.31% | +6.08% |
| 2025 | +9.24% | +16.74% |
| 2024 | +2.42% | +16.21% |
| 2023 | -4.20% | N/A |
FMED vs NXTI Drawdown Comparison
The maximum drawdown for FMED was -21.84%, occurring on Oct 30, 2023. Recovery took 151 trading sessions.
The maximum drawdown for NXTI was -19.65%, occurring on Apr 8, 2025. Recovery took 91 trading sessions.
The current FMED drawdown is -15.43%. The current NXTI drawdown is -3.36%.
| Rank | FMED | NXTI |
|---|---|---|
| #1 | -21.84% Jul 21, 2023 - Feb 27, 2024 | -19.65% Feb 18, 2025 - Jun 30, 2025 |
| #2 | -19.46% Jan 30, 2025 - Oct 27, 2025 | -12.99% Dec 11, 2025 - May 22, 2026 |
| #3 | -18.33% Nov 28, 2025 - Mar 30, 2026 | -7.25% Oct 27, 2025 - Dec 10, 2025 |
| #4 | -8.49% Feb 27, 2024 - Aug 21, 2024 | -6.70% Dec 4, 2024 - Feb 4, 2025 |
| #5 | -7.13% Sep 19, 2024 - Dec 4, 2024 | -6.41% Jul 16, 2024 - Aug 15, 2024 |
| #6 | -6.80% Dec 4, 2024 - Jan 30, 2025 | -3.72% Sep 29, 2025 - Oct 27, 2025 |
| #7 | -4.70% Oct 27, 2025 - Nov 11, 2025 | -3.53% Jun 1, 2026 - Jun 5, 2026 |
| #8 | -4.36% Jun 13, 2023 - Jul 21, 2023 | -3.24% Oct 14, 2024 - Nov 6, 2024 |
| #9 | -1.91% Aug 29, 2024 - Sep 12, 2024 | -3.20% Aug 30, 2024 - Sep 13, 2024 |
| #10 | -1.33% Nov 12, 2025 - Nov 19, 2025 | -3.01% May 21, 2024 - Jun 18, 2024 |
| #11 | -0.82% Sep 16, 2024 - Sep 19, 2024 | -2.50% Jul 28, 2025 - Aug 12, 2025 |
| #12 | -0.51% Nov 19, 2025 - Nov 21, 2025 | -2.28% Nov 13, 2024 - Nov 22, 2024 |
| #13 | -0.40% Aug 23, 2024 - Aug 27, 2024 | -2.12% Jul 3, 2025 - Jul 25, 2025 |
| #14 | -0.16% Aug 27, 2024 - Aug 29, 2024 | -2.07% Apr 23, 2024 - May 6, 2024 |
| #15 | -0.12% Aug 21, 2024 - Aug 23, 2024 | -1.47% Aug 13, 2025 - Aug 28, 2025 |
Correlation
Correlation between FMED and NXTI is 0.39 which considered as a weak positive correlation - the stocks show a slight tendency to move together.
0.39
-101
Dividend Comparison (2024 - 2026)
FMED vs NXTI dividend yield comparison.
| Year | FMED | NXTI |
|---|---|---|
| 2026 | 0.00% | 0.15% |
| 2025 | 0.00% | 0.62% |
| 2024 | 0.46% | 3.70% |
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