DYN vs ICUI

Comparison between Dyne Therapeutics Inc (DYN, Company) and ICU Medical Inc (ICUI, Company).

Both DYN and ICUI are from the Healthcare sector.

5-Year PerformanceDYN has outperformed ICUI, delivering a return of +4.9% compared to -4.2%

DYN vs ICUI - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	DYN(COMPANY)	ICUI(COMPANY)
Market Cap	$3.96B	$3.95B
Max Drawdown	85.52%	73.82%
Sharpe Ratio	1.58	0.59
5Y Beta	1.78	1.13
Industry	Biotechnology	Medical Instruments & Supplies
P/E Ratio	-7.65	84.82
Forward P/E	N/A	19.30
5Y EPS CAGR	N/A	-16.01%
Debt to Equity	17.27%	60.64%
Free Cash Flow Yield	-11.19%	2.09%

Market Cap

Winner

DYN

$3.96B

ICUI

$3.95B

Max Drawdown

DYN

85.52%

Winner

ICUI

73.82%

Sharpe Ratio

Winner

DYN

1.58

ICUI

0.59

5Y Beta

DYN

1.78

Winner

ICUI

1.13

Industry

DYN

Biotechnology

ICUI

Medical Instruments & Supplies

P/E Ratio

Winner

DYN

-7.65

ICUI

84.82

Forward P/E

DYN

N/A

ICUI

19.30

5Y EPS CAGR

DYN

N/A

ICUI

-16.01%

Debt to Equity

Winner

DYN

17.27%

ICUI

60.64%

Free Cash Flow Yield

DYN

-11.19%

Winner

ICUI

2.09%

DYN vs ICUI - Historical Returns

Returns include dividend reinvestment.

Period	DYN	ICUI
1 month	+28.08%	+9.91%
3 months	+20.07%	+25.16%
6 months	+46.10%	+1.83%
1 year	+189.73%	+24.88%
5 years(CAGR)	+4.89%	-4.22%
10 years(CAGR)	N/A	+3.43%
Max(CAGR)	+0.06%	+11.10%

Winner

DYN

+28.08%

ICUI

+9.91%

DYN

+20.07%

Winner

ICUI

+25.16%

Winner

DYN

+46.10%

ICUI

+1.83%

Winner

DYN

+189.73%

ICUI

+24.88%

5Y(CAGR)

Winner

DYN

+4.89%

ICUI

-4.22%

10Y(CAGR)

DYN

N/A

ICUI

+3.43%

Max(CAGR)

DYN

+0.06%

Winner

ICUI

+11.10%

DYN vs ICUI - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	DYN	ICUI
2026	+29.68%	+14.03%
2025	-23.17%	-9.69%
2024	+80.40%	+52.76%
2023	+13.68%	-37.59%
2022	-5.54%	-33.38%
2021	-37.45%	+11.92%
2020	-12.13%	+15.55%
2019	N/A	-17.13%
2018	N/A	+6.26%
2017	N/A	+46.74%
2016	N/A	+40.12%
2015	N/A	+40.15%
2014	N/A	+30.43%
2013	N/A	+3.26%
2012	N/A	+36.40%
2011	N/A	+23.56%
2010	N/A	-0.63%
2009	N/A	+10.36%
2008	N/A	-9.06%
2007	N/A	-12.13%
2006	N/A	+0.67%
2005	N/A	+48.64%
2004	N/A	-18.97%
2003	N/A	-8.14%
2002	N/A	+24.33%
2001	N/A	+56.14%
2000	N/A	+106.09%
1999	N/A	+7.02%

DYN vs ICUI Drawdown Comparison

The maximum drawdown for DYN was -85.52%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The maximum drawdown for ICUI was -73.82%, occurring on Nov 9, 2023. This drawdown has not yet recovered.

The current DYN drawdown is -49.00%. The current ICUI drawdown is -49.00%.

Rank	DYN	ICUI
#1	-85.52% Aug 21, 2024 - Apr 8, 2025	-73.82% Jun 14, 2018 - Nov 9, 2023
#2	-85.12% Jan 13, 2021 - May 15, 2024	-53.08% Oct 12, 2006 - Mar 16, 2012
#3	-29.67% Sep 17, 2020 - Nov 3, 2020	-49.92% Nov 22, 2002 - Aug 30, 2006
#4	-21.47% Nov 3, 2020 - Jan 8, 2021	-38.65% May 3, 2002 - Nov 21, 2002
#5	-15.18% May 20, 2024 - Jun 24, 2024	-36.21% Jul 5, 2000 - Mar 1, 2001
#6	-8.31% Jul 26, 2024 - Aug 15, 2024	-29.75% Aug 17, 2015 - Aug 9, 2016
#7	-6.25% Jul 16, 2024 - Jul 26, 2024	-28.60% Jul 10, 2013 - Nov 11, 2014
#8	-5.79% May 15, 2024 - May 20, 2024	-20.50% Jan 14, 2000 - Mar 3, 2000
#9	-5.67% Jun 24, 2024 - Jul 9, 2024	-19.40% May 11, 2000 - Jun 21, 2000
#10	-1.00% Jul 11, 2024 - Jul 15, 2024	-16.03% Jun 26, 2001 - Oct 18, 2001
#11	-0.85% Jan 8, 2021 - Jan 12, 2021	-14.46% Mar 21, 2000 - Apr 25, 2000
#12	-0.77% Aug 15, 2024 - Aug 19, 2024	-14.34% Oct 26, 2001 - Jan 17, 2002
#13	N/A	-13.69% Apr 27, 2001 - Jun 5, 2001
#14	N/A	-13.10% Dec 14, 2016 - Feb 17, 2017
#15	N/A	-12.71% Mar 7, 2000 - Mar 21, 2000