DYAI vs VTGN

Comparison between Dyadic International Inc DE (DYAI, Company) and VistaGen Therapeutics Inc (VTGN, Company).

Both DYAI and VTGN are from the Healthcare sector.

5-Year PerformanceDYAI has outperformed VTGN, delivering a return of -25.2% compared to -62.2%

DYAI vs VTGN - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	DYAI(COMPANY)	VTGN(COMPANY)
Market Cap	$28M	$26M
Max Drawdown	93.42%	99.76%
Sharpe Ratio	0.08	-0.15
5Y Beta	0.47	0.96
Industry	Biotechnology	Biotechnology
P/E Ratio	-3.70	-0.35
Forward P/E	15.82	N/A
PEG Ratio	-0.48	-0.01
5Y EPS CAGR	-7.16%	-12.57%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-20.06%	N/A

Market Cap

Winner

DYAI

$28M

VTGN

$26M

Max Drawdown

Winner

DYAI

93.42%

VTGN

99.76%

Sharpe Ratio

Winner

DYAI

0.08

VTGN

-0.15

5Y Beta

Winner

DYAI

0.47

VTGN

0.96

Industry

DYAI

Biotechnology

VTGN

Biotechnology

P/E Ratio

Winner

DYAI

-3.70

VTGN

-0.35

Forward P/E

DYAI

15.82

VTGN

N/A

PEG Ratio

Winner

DYAI

-0.48

VTGN

-0.01

5Y EPS CAGR

Winner

DYAI

-7.16%

VTGN

-12.57%

Debt to Equity

DYAI

0.00%

VTGN

0.00%

Free Cash Flow Yield

DYAI

-20.06%

VTGN

N/A

DYAI vs VTGN - Historical Returns

Returns include dividend reinvestment.

Period	DYAI	VTGN
1 month	+8.60%	+12.54%
3 months	+0.26%	+9.87%
6 months	-14.05%	-9.43%
1 year	-21.01%	-67.47%
5 years(CAGR)	-25.25%	-62.19%
10 years(CAGR)	-7.36%	-39.65%
Max(CAGR)	-7.62%	-43.34%

DYAI

+8.60%

Winner

VTGN

+12.54%

DYAI

+0.26%

Winner

VTGN

+9.87%

DYAI

-14.05%

Winner

VTGN

-9.43%

Winner

DYAI

-21.01%

VTGN

-67.47%

5Y(CAGR)

Winner

DYAI

-25.25%

VTGN

-62.19%

10Y(CAGR)

Winner

DYAI

-7.36%

VTGN

-39.65%

Max(CAGR)

Winner

DYAI

-7.62%

VTGN

-43.34%

DYAI vs VTGN - Annual Returns (2016 - 2026)

Returns include dividend reinvestment.

Year	DYAI	VTGN
2026	-16.80%	-1.30%
2025	-45.98%	-80.03%
2024	+10.06%	-42.72%
2023	+16.67%	+31.79%
2022	-74.43%	-95.07%
2021	-12.40%	-14.85%
2020	+2.09%	+158.67%
2019	+183.06%	-56.60%
2018	+35.00%	+29.31%
2017	-16.77%	-70.26%
2016	-7.26%	-46.71%

DYAI vs VTGN Drawdown Comparison

The maximum drawdown for DYAI was -93.42%, occurring on Jun 9, 2026. This drawdown has not yet recovered.

The maximum drawdown for VTGN was -99.76%, occurring on Feb 5, 2026. This drawdown has not yet recovered.

The current DYAI drawdown is -92.38%. The current VTGN drawdown is -99.68%.

Rank	DYAI	VTGN
#1	-93.42% Jun 22, 2020 - Jun 9, 2026	-99.76% May 6, 2016 - Feb 5, 2026
#2	-62.88% Jun 19, 2019 - Jun 10, 2020	N/A
#3	-30.94% Jan 9, 2017 - Oct 4, 2018	N/A
#4	-25.23% Oct 5, 2018 - Feb 14, 2019	N/A
#5	-21.79% Jan 4, 2016 - Jan 6, 2017	N/A
#6	-13.04% Jun 10, 2020 - Jun 12, 2020	N/A
#7	-12.56% May 22, 2019 - Jun 3, 2019	N/A
#8	-12.36% May 10, 2019 - May 22, 2019	N/A
#9	-9.44% Apr 26, 2019 - May 9, 2019	N/A
#10	-9.25% Jun 6, 2019 - Jun 17, 2019	N/A
#11	-8.70% Apr 1, 2019 - Apr 15, 2019	N/A
#12	-6.68% Jun 15, 2020 - Jun 19, 2020	N/A
#13	-4.49% Apr 15, 2019 - Apr 26, 2019	N/A
#14	-4.20% Feb 25, 2019 - Mar 13, 2019	N/A
#15	-1.74% Mar 13, 2019 - Mar 18, 2019	N/A