DRRX vs SCLX

Comparison between Durect Corp (DRRX, Company) and Scilex Holding Company (SCLX, Company).

Both DRRX and SCLX are from the Healthcare sector.

5-Year PerformanceDRRX has outperformed SCLX, delivering a return of -34.6% compared to -49.9%

DRRX vs SCLX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	DRRX(COMPANY)	SCLX(COMPANY)
Market Cap	$60M	$60M
Max Drawdown	99.68%	99.23%
Sharpe Ratio	0.66	0.53
5Y Beta	N/A	1.02
Industry	Drug Manufacturers - Specialty & Generic	Drug Manufacturers - General
P/E Ratio	-17.21	-0.16
Forward P/E	N/A	2.66
PEG Ratio	N/A	-0.00
Debt to Equity	0.00%	-32.41%
Free Cash Flow Yield	-23.46%	-5.75%
P/S Ratio	-49.64	1.53
P/B Ratio	17.09	28.85

Market Cap

DRRX

$60M

Winner

SCLX

$60M

Max Drawdown

DRRX

99.68%

Winner

SCLX

99.23%

Sharpe Ratio

Winner

DRRX

0.66

SCLX

0.53

5Y Beta

DRRX

N/A

SCLX

1.02

Industry

DRRX

Drug Manufacturers - Specialty & Generic

SCLX

Drug Manufacturers - General

P/E Ratio

Winner

DRRX

-17.21

SCLX

-0.16

Forward P/E

DRRX

N/A

SCLX

2.66

PEG Ratio

DRRX

N/A

SCLX

-0.00

Debt to Equity

DRRX

0.00%

Winner

SCLX

-32.41%

Free Cash Flow Yield

DRRX

-23.46%

Winner

SCLX

-5.75%

P/S Ratio

Winner

DRRX

-49.64

SCLX

1.53

P/B Ratio

Winner

DRRX

17.09

SCLX

28.85

DRRX vs SCLX - Historical Returns

Returns include dividend reinvestment.

Period	DRRX	SCLX
1 month	+2.14%	-0.29%
3 months	+218.33%	+64.20%
6 months	+133.38%	-0.05%
1 year	+21.66%	+2.47%
5 years(CAGR)	-34.63%	-49.89%
10 years(CAGR)	-22.33%	N/A
Max(CAGR)	-15.91%	-47.27%

Winner

DRRX

+2.14%

SCLX

-0.29%

Winner

DRRX

+218.33%

SCLX

+64.20%

Winner

DRRX

+133.38%

SCLX

-0.05%

Winner

DRRX

+21.66%

SCLX

+2.47%

5Y(CAGR)

Winner

DRRX

-34.63%

SCLX

-49.89%

10Y(CAGR)

DRRX

-22.33%

SCLX

N/A

Max(CAGR)

Winner

DRRX

-15.91%

SCLX

-47.27%

DRRX vs SCLX - Annual Returns (2000 - 2026)

Returns include dividend reinvestment.

Year	DRRX	SCLX
2026	N/A	-16.08%
2025	+141.53%	-20.13%
2024	+35.14%	-79.10%
2023	-83.61%	-61.61%
2022	-64.51%	-60.30%
2021	-53.05%	+1.93%
2020	-20.99%	N/A
2019	+603.44%	N/A
2018	-47.49%	N/A
2017	-31.34%	N/A
2016	-34.31%	N/A
2015	+166.27%	N/A
2014	-54.38%	N/A
2013	+80.21%	N/A
2012	-23.33%	N/A
2011	-67.13%	N/A
2010	+34.77%	N/A
2009	-25.15%	N/A
2008	-45.41%	N/A
2007	+46.47%	N/A
2006	-12.43%	N/A
2005	+62.50%	N/A
2004	+24.24%	N/A
2003	+17.92%	N/A
2002	-81.72%	N/A
2001	+4.13%	N/A
2000	-16.72%	N/A

DRRX vs SCLX Drawdown Comparison

The maximum drawdown for DRRX was -99.68%, occurring on May 27, 2025. This drawdown has not yet recovered.

The maximum drawdown for SCLX was -99.23%, occurring on Apr 22, 2025. This drawdown has not yet recovered.

The current DRRX drawdown is -98.79%. The current SCLX drawdown is -97.88%.

Rank	DRRX	SCLX
#1	-99.68% Nov 6, 2000 - May 27, 2025	-99.23% Apr 12, 2023 - Apr 22, 2025
#2	-23.81% Oct 6, 2000 - Nov 6, 2000	-72.67% Nov 8, 2022 - Jan 19, 2023
#3	-8.73% Sep 29, 2000 - Oct 6, 2000	-42.23% Jan 20, 2023 - Apr 5, 2023
#4	N/A	-16.08% Oct 26, 2022 - Nov 8, 2022
#5	N/A	-8.13% Apr 10, 2023 - Apr 12, 2023
#6	N/A	-1.26% Jun 27, 2022 - Oct 13, 2022
#7	N/A	-1.21% Mar 11, 2021 - Apr 19, 2021
#8	N/A	-0.80% Apr 19, 2021 - Aug 30, 2021
#9	N/A	-0.59% Nov 2, 2021 - Jan 24, 2022
#10	N/A	-0.50% Oct 18, 2021 - Nov 2, 2021
#11	N/A	-0.40% Jan 24, 2022 - Feb 2, 2022
#12	N/A	-0.39% Mar 17, 2022 - May 4, 2022
#13	N/A	-0.29% May 5, 2022 - May 25, 2022
#14	N/A	-0.29% May 27, 2022 - Jun 21, 2022
#15	N/A	-0.28% Sep 14, 2021 - Oct 14, 2021