DNLI vs KAR

Comparison between Denali Therapeutics Inc (DNLI, Company) and Openlane Inc (KAR, Company).

DNLI is from the Healthcare sector, while KAR is from the Consumer Cyclical sector.

5-Year PerformanceKAR has outperformed DNLI, delivering a return of +11.2% compared to -22.5%

DNLI vs KAR - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	DNLI(COMPANY)	KAR(COMPANY)
Market Cap	$3.27B	$3.27B
Max Drawdown	87.74%	65.52%
Sharpe Ratio	0.78	1.28
5Y Beta	1.53	0.90
Industry	Biotechnology	Auto & Truck Dealerships
P/E Ratio	-6.15	17.31
Forward P/E	N/A	23.67
PEG Ratio	-0.96	0.35
5Y Dividends CAGR	N/A	16.68%
5Y EPS CAGR	N/A	43.82%
Debt to Equity	0.00%	44.24%
Free Cash Flow Yield	-12.91%	15.65%
P/S Ratio	3643.65	N/A
P/B Ratio	3.53	N/A

Market Cap

DNLI

$3.27B

Winner

KAR

$3.27B

Max Drawdown

DNLI

87.74%

Winner

KAR

65.52%

Sharpe Ratio

DNLI

0.78

Winner

KAR

1.28

5Y Beta

DNLI

1.53

Winner

KAR

0.90

Industry

DNLI

Biotechnology

KAR

Auto & Truck Dealerships

P/E Ratio

Winner

DNLI

-6.15

KAR

17.31

Forward P/E

DNLI

N/A

KAR

23.67

PEG Ratio

Winner

DNLI

-0.96

KAR

0.35

5Y Dividends CAGR

DNLI

N/A

KAR

16.68%

5Y EPS CAGR

DNLI

N/A

KAR

43.82%

Debt to Equity

Winner

DNLI

0.00%

KAR

44.24%

Free Cash Flow Yield

DNLI

-12.91%

Winner

KAR

15.65%

P/S Ratio

DNLI

3643.65

KAR

N/A

P/B Ratio

DNLI

3.53

KAR

N/A

DNLI vs KAR - Historical Returns

Returns include dividend reinvestment.

Period	DNLI	KAR
1 month	+6.86%	+25.38%
3 months	-2.73%	+9.16%
6 months	+21.01%	+34.91%
1 year	+38.38%	+50.63%
5 years(CAGR)	-22.46%	+11.18%
10 years(CAGR)	-0.24%	+9.62%
Max(CAGR)	-0.24%	+14.32%

DNLI

+6.86%

Winner

KAR

+25.38%

DNLI

-2.73%

Winner

KAR

+9.16%

DNLI

+21.01%

Winner

KAR

+34.91%

DNLI

+38.38%

Winner

KAR

+50.63%

5Y(CAGR)

DNLI

-22.46%

Winner

KAR

+11.18%

10Y(CAGR)

DNLI

-0.24%

Winner

KAR

+9.62%

Max(CAGR)

DNLI

-0.24%

Winner

KAR

+14.32%

DNLI vs KAR - Annual Returns (2009 - 2026)

Returns include dividend reinvestment.

Year	DNLI	KAR
2026	+29.19%	N/A
2025	-20.78%	+53.02%
2024	-4.72%	+33.51%
2023	-22.33%	+12.20%
2022	-41.17%	-17.77%
2021	-37.06%	-15.11%
2020	+411.04%	-15.65%
2019	-9.88%	+26.94%
2018	+28.08%	-3.93%
2017	-27.09%	+19.99%
2016	N/A	+18.88%
2015	N/A	+10.39%
2014	N/A	+19.88%
2013	N/A	+48.55%
2012	N/A	+49.89%
2011	N/A	-4.05%
2010	N/A	-1.22%
2009	N/A	+14.63%

DNLI vs KAR Drawdown Comparison

The maximum drawdown for DNLI was -87.74%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The maximum drawdown for KAR was -64.43%, occurring on Apr 3, 2020. Recovery took 1483 trading sessions.

The current DNLI drawdown is -77.53%.

Rank	DNLI	KAR
#1	-87.74% Dec 22, 2020 - Apr 8, 2025	-64.43% Sep 11, 2019 - Aug 6, 2025
#2	-49.76% Feb 16, 2018 - Apr 2, 2019	-44.91% May 31, 2011 - Jan 16, 2013
#3	-49.54% Apr 10, 2019 - Jun 2, 2020	-28.86% May 3, 2010 - Apr 1, 2011
#4	-29.88% Dec 8, 2017 - Jan 22, 2018	-28.04% Aug 21, 2018 - Jun 20, 2019
#5	-19.74% Jun 3, 2020 - Aug 6, 2020	-18.30% Jul 3, 2014 - Nov 5, 2014
#6	-19.58% Jan 29, 2018 - Feb 16, 2018	-17.88% Aug 10, 2015 - Apr 13, 2016
#7	-13.33% Nov 12, 2020 - Dec 4, 2020	-17.32% Sep 11, 2025 - Dec 16, 2025
#8	-11.16% Aug 10, 2020 - Aug 25, 2020	-13.02% Feb 19, 2013 - Apr 29, 2013
#9	-10.43% Sep 17, 2020 - Oct 7, 2020	-12.42% Feb 15, 2017 - Sep 20, 2017
#10	-10.33% Oct 13, 2020 - Oct 27, 2020	-11.90% Oct 5, 2016 - Jan 4, 2017
#11	-9.64% Aug 25, 2020 - Sep 14, 2020	-11.12% Jan 26, 2018 - Mar 6, 2018
#12	-7.28% Oct 28, 2020 - Nov 4, 2020	-11.11% Jan 20, 2010 - Mar 22, 2010
#13	-3.20% Jan 23, 2018 - Jan 26, 2018	-10.19% May 17, 2013 - Jul 8, 2013
#14	-2.37% Apr 3, 2019 - Apr 5, 2019	-10.15% Oct 21, 2013 - Jan 3, 2014
#15	-1.33% Dec 16, 2020 - Dec 18, 2020	-9.11% Jul 30, 2019 - Sep 9, 2019

Correlation

Correlation between DNLI and KAR is -0.34 which considered as a weak negative correlation - the stocks show a slight tendency to move in opposite directions.

-0.34

-101