DNLI vs ADPT

Comparison between Denali Therapeutics Inc (DNLI, Company) and Adaptive Biotechnologies Corp (ADPT, Company).

Both DNLI and ADPT are from the Healthcare sector.

5-Year PerformanceADPT has outperformed DNLI, delivering a return of -8.3% compared to -18.6%

DNLI vs ADPT - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	DNLI(COMPANY)	ADPT(COMPANY)
Market Cap	$3.65B	$3.66B
Max Drawdown	87.74%	96.55%
Sharpe Ratio	1.00	1.28
5Y Beta	1.48	1.72
Industry	Biotechnology	Diagnostics & Research
P/E Ratio	-6.87	-71.69
PEG Ratio	-1.07	N/A
5Y EPS CAGR	N/A	-22.53%
Debt to Equity	0.00%	60.35%
Free Cash Flow Yield	-11.55%	-0.81%

Market Cap

DNLI

$3.65B

Winner

ADPT

$3.66B

Max Drawdown

Winner

DNLI

87.74%

ADPT

96.55%

Sharpe Ratio

DNLI

1.00

Winner

ADPT

1.28

5Y Beta

Winner

DNLI

1.48

ADPT

1.72

Industry

DNLI

Biotechnology

ADPT

Diagnostics & Research

P/E Ratio

DNLI

-6.87

Winner

ADPT

-71.69

PEG Ratio

DNLI

-1.07

ADPT

N/A

5Y EPS CAGR

DNLI

N/A

ADPT

-22.53%

Debt to Equity

Winner

DNLI

0.00%

ADPT

60.35%

Free Cash Flow Yield

DNLI

-11.55%

Winner

ADPT

-0.81%

DNLI vs ADPT - Historical Returns

Returns include dividend reinvestment.

Period	DNLI	ADPT
1 month	+3.60%	+31.16%
3 months	+6.18%	+57.60%
6 months	+22.58%	+28.80%
1 year	+62.46%	+107.05%
5 years(CAGR)	-18.55%	-8.26%
10 years(CAGR)	+0.82%	N/A
Max(CAGR)	+0.82%	-7.70%

DNLI

+3.60%

Winner

ADPT

+31.16%

DNLI

+6.18%

Winner

ADPT

+57.60%

DNLI

+22.58%

Winner

ADPT

+28.80%

DNLI

+62.46%

Winner

ADPT

+107.05%

5Y(CAGR)

DNLI

-18.55%

Winner

ADPT

-8.26%

10Y(CAGR)

DNLI

+0.82%

ADPT

N/A

Max(CAGR)

Winner

DNLI

+0.82%

ADPT

-7.70%

DNLI vs ADPT - Annual Returns (2017 - 2026)

Returns include dividend reinvestment.

Year	DNLI	ADPT
2026	+41.49%	+43.93%
2025	-20.78%	+162.36%
2024	-4.72%	+25.68%
2023	-22.33%	-37.18%
2022	-41.17%	-73.56%
2021	-37.06%	-49.74%
2020	+411.04%	+101.33%
2019	-9.88%	-25.76%
2018	+28.08%	N/A
2017	-27.09%	N/A

DNLI vs ADPT Drawdown Comparison

The maximum drawdown for DNLI was -87.74%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The maximum drawdown for ADPT was -96.55%, occurring on Apr 18, 2024. This drawdown has not yet recovered.

The current DNLI drawdown is -75.40%. The current ADPT drawdown is -66.19%.

Rank	DNLI	ADPT
#1	-87.74% Dec 22, 2020 - Apr 8, 2025	-96.55% Jan 22, 2021 - Apr 18, 2024
#2	-49.76% Feb 16, 2018 - Apr 2, 2019	-68.30% Sep 4, 2019 - Dec 10, 2020
#3	-49.54% Apr 10, 2019 - Jun 2, 2020	-27.29% Jun 28, 2019 - Aug 29, 2019
#4	-29.88% Dec 8, 2017 - Jan 22, 2018	-14.85% Dec 23, 2020 - Jan 14, 2021
#5	-19.74% Jun 3, 2020 - Aug 6, 2020	-2.05% Dec 14, 2020 - Dec 17, 2020
#6	-19.58% Jan 29, 2018 - Feb 16, 2018	-0.85% Jan 14, 2021 - Jan 19, 2021
#7	-13.33% Nov 12, 2020 - Dec 4, 2020	-0.71% Jan 19, 2021 - Jan 22, 2021
#8	-11.16% Aug 10, 2020 - Aug 25, 2020	N/A
#9	-10.43% Sep 17, 2020 - Oct 7, 2020	N/A
#10	-10.33% Oct 13, 2020 - Oct 27, 2020	N/A
#11	-9.64% Aug 25, 2020 - Sep 14, 2020	N/A
#12	-7.28% Oct 28, 2020 - Nov 4, 2020	N/A
#13	-3.20% Jan 23, 2018 - Jan 26, 2018	N/A
#14	-2.37% Apr 3, 2019 - Apr 5, 2019	N/A
#15	-1.33% Dec 16, 2020 - Dec 18, 2020	N/A