DMAC vs NAUT

Comparison between DiaMedica Therapeutics Inc (DMAC, Company) and Nautilus Biotechnology Inc (NAUT, Company).

Both DMAC and NAUT are from the Healthcare sector.

5-Year PerformanceDMAC has outperformed NAUT, delivering a return of -8.8% compared to -26.5%

DMAC vs NAUT - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	DMAC(COMPANY)	NAUT(COMPANY)
Market Cap	$287M	$287M
Max Drawdown	98.16%	94.19%
Sharpe Ratio	0.69	1.53
5Y Beta	1.23	1.81
Industry	Biotechnology	Biotechnology
P/E Ratio	-7.69	-5.01
PEG Ratio	-0.78	N/A
5Y EPS CAGR	-1.88%	N/A
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-10.80%	-17.91%
P/S Ratio	66.68	N/A
P/B Ratio	6.08	1.99

Market Cap

Winner

DMAC

$287M

NAUT

$287M

Max Drawdown

DMAC

98.16%

Winner

NAUT

94.19%

Sharpe Ratio

DMAC

0.69

Winner

NAUT

1.53

5Y Beta

Winner

DMAC

1.23

NAUT

1.81

Industry

DMAC

Biotechnology

NAUT

Biotechnology

P/E Ratio

Winner

DMAC

-7.69

NAUT

-5.01

PEG Ratio

DMAC

-0.78

NAUT

N/A

5Y EPS CAGR

DMAC

-1.88%

NAUT

N/A

Debt to Equity

DMAC

0.00%

NAUT

0.00%

Free Cash Flow Yield

Winner

DMAC

-10.80%

NAUT

-17.91%

P/S Ratio

DMAC

66.68

NAUT

N/A

P/B Ratio

DMAC

6.08

Winner

NAUT

1.99

DMAC vs NAUT - Historical Returns

Returns include dividend reinvestment.

Period	DMAC	NAUT
1 month	-10.60%	-23.55%
3 months	-21.96%	-2.18%
6 months	-39.83%	+21.08%
1 year	+44.87%	+213.86%
5 years(CAGR)	-8.81%	-26.50%
10 years(CAGR)	+5.21%	N/A
Max(CAGR)	-7.94%	-27.24%

Winner

DMAC

-10.60%

NAUT

-23.55%

DMAC

-21.96%

Winner

NAUT

-2.18%

DMAC

-39.83%

Winner

NAUT

+21.08%

DMAC

+44.87%

Winner

NAUT

+213.86%

5Y(CAGR)

Winner

DMAC

-8.81%

NAUT

-26.50%

10Y(CAGR)

DMAC

+5.21%

NAUT

N/A

Max(CAGR)

Winner

DMAC

-7.94%

NAUT

-27.24%

DMAC vs NAUT - Annual Returns (2008 - 2026)

Returns include dividend reinvestment.

Year	DMAC	NAUT
2026	-28.75%	+17.28%
2025	+44.46%	+15.38%
2024	+91.87%	-44.37%
2023	+91.89%	+76.92%
2022	-59.28%	-66.04%
2021	-62.85%	-52.91%
2020	+108.64%	N/A
2019	+50.15%	N/A
2018	-40.34%	N/A
2017	+127.69%	N/A
2016	+15.58%	N/A
2015	+90.00%	N/A
2014	-93.50%	N/A
2013	-33.49%	N/A
2012	-25.92%	N/A
2011	+64.60%	N/A
2010	+95.49%	N/A
2009	-58.86%	N/A
2008	-9.15%	N/A

DMAC vs NAUT Drawdown Comparison

The maximum drawdown for DMAC was -98.16%, occurring on Dec 5, 2014. This drawdown has not yet recovered.

The maximum drawdown for NAUT was -94.19%, occurring on Sep 3, 2025. This drawdown has not yet recovered.

The current DMAC drawdown is -87.21%. The current NAUT drawdown is -79.64%.

Rank	DMAC	NAUT
#1	-98.16% Aug 7, 2012 - Dec 5, 2014	-94.19% Jun 10, 2021 - Sep 3, 2025
#2	-73.05% Jan 4, 2008 - Jan 25, 2011	N/A
#3	-36.88% Mar 8, 2011 - Feb 27, 2012	N/A
#4	-25.49% Feb 28, 2012 - Jul 31, 2012	N/A
#5	-16.15% Jan 27, 2011 - Mar 8, 2011	N/A